Search Results - "SERNEELS, S"

spatial distribution of vegetation types in the Serengeti ecosystem: the influence of rainfall and topographic relief on vegetation patch characteristics by Reed, D.N, Anderson, T.M, Dempewolf, J, Metzger, K, Serneels, S

“…The aim of this study is to introduce a structural vegetation map of the Serengeti ecosystem and, based on the map, to test the relative influences of…”
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Progranulin genetic variability contributes to amyotrophic lateral sclerosis by SLEEGERS, K, BROUWERS, N, CRUTS, M, SCHYMKOWITZ, J, DE JONGHE, P, ROUSSEAU, F, VAN DEN BERG, L. H, ROBBERECHT, W, VAN BROECKHOVEN, C, MAURER-STROH, S, VAN ES, M. A, VAN DAMME, P, VAN VUGHT, P. W. J, VAN DER ZEE, J, SERNEELS, S, DE POORER, T, VAN DEN BROECK, M

“…Null mutations in progranulin (PGRN) cause ubiquitin-positive frontotemporal dementia (FTD) linked to chromosome 17q21 (FTDU-17). Here we examined PGRN genetic…”
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Long-Term Changes in Serengeti-Mara Wildebeest and Land Cover: Pastoralism, Population, or Policies? by Homewood, K., Lambin, E. F., Coast, E., Kariuki, A., Kikula, I., Kivelia, J., Said, M., Serneels, S., Thompson, M.

“…Declines in habitat and wildlife in semiarid African savannas are widely reported and commonly attributed to agropastoral population growth, livestock impacts,…”
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Estimation of the Genetic Contribution of Presenilin-1 and -2 Mutations in a Population-Based Study of Presenile Alzheimer Disease by Cruts, Marc, van Duijn, Cornelia M., Backhovens, Hubert, Van den Broeck, Marleen, Wehnert, Anita, Serneels, Sally, Sherrington, Robin, Hutton, Michael, Hardy, John, St George-Hyslop, Peter H., Hofman, Albert, Van Broeckhoven, Christine

“…Two closely related genes, the presenilins (PS), located at chromosomes 14q24.3 and 1q42.1, have been identified for autosomal dominant Alzheimer disease (AD)…”
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Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects by Engelborghs, S, Dermaut, B, Goeman, J, Saerens, J, Mariën, P, Pickut, BA, Van den Broeck, M, Serneels, S, Cruts, M, Van Broeckhoven, C, De Deyn, P P

“…Objective: The authors conducted a prospective study of neurodegenerative and vascular dementia in Belgium. Strict diagnostic inclusion criteria were used to…”
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Land cover changes around a major east African wildlife reserve: The Mara Ecosystem (Kenya) by Serneels, S., Said, M. Y., Lambin, E. F.

“…The dynamics of savannah vegetation are still poorly understood. This study aims at analysing land cover changes over the past 20 years in the rangelands area…”
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Multilevel Analysis of the Impact of Land Use on Interannual Land-Cover Change in East Africa by Serneels, S, Linderman, M, Lambin, E. F

“…The aim of this study was to characterize the short-term land-cover change processes that were detected in Eastern Africa, based on a set of change metrics…”
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Impact of ENSO on East African ecosystems: a multivariate analysis based on climate and remote sensing data by Plisnier, P. D., Serneels, S., Lambin, E. F.

“…1 The El Nino-Southern Oscillation (ENSO) is an important driver of inter-annual variations in climate and ecosystem productivity in tropical regions. Most…”
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Effect of the APOE-491A/T promoter polymorphism on apolipoprotein E levels and risk of Alzheimer disease: The Rotterdam Study by Roks, G., Cruts, M., Houwing-Duistermaat, J.J., Dermaut, B., Serneels, S., Havekes, L.M., Hofman, A., Breteler, M.M.B., Van Broeckhoven, C., van Duijn, C.M.

“…The apolipoprotein E (APOE) gene is involved in lipid transport. A common polymorphism in this gene with the APOE*2, APOE*3, and APOE*4 alleles influences…”
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Cellwise robust M regression by Filzmoser, P., Höppner, S., Ortner, I., Serneels, S., Verdonck, T.

“…The cellwise robust M regression estimator is introduced as the first estimator of its kind that intrinsically yields both a map of cellwise outliers…”
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Synaptopodin and 4 novel genes identified in primary sensory neurons by Verpoorten, Nathalie, Verhoeven, Kristien, Weckx, Stefan, Jacobs, An, Serneels, Sally, Del Favero, Jurgen, Ceuterick, Chantal, Van Bockstaele, Dirk R., Berneman, Zwi N., Van Den Bosch, Ludo, Robberecht, Wim, Nobbio, Lucilla, Schenone, Angelo, Dessaud, Eric, deLapeyrière, Odile, Huylebroeck, Danny, Zwijsen, An, De Jonghe, Peter, Timmerman, Vincent

“…We performed differential gene expression profiling in the peripheral nervous system by comparing the transcriptome of sensory neurons with the transcriptome…”
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Variable expression of presenilin 1 is not a major determinant of risk for late-onset Alzheimer's disease by DERMAUT, B, ROKS, G, VAN DUIJN, C. M, THEUNS, J, RADEMAKERS, R, HOUWING-DUISTERMAAT, J. J, SERNEELS, S, HOFMAN, A, BRETELER, M. M. B, CRUTS, M, VAN BROECKHOVEN, C

“…We have previously reported a significant association between early-onset Alzheimer's disease (EOAD) and an allele in the promoter of presenilin 1 (PSEN1)…”
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Partial robust M-regression by Serneels, Sven, Croux, Christophe, Filzmoser, Peter, Van Espen, Pierre J.

“…Partial Least Squares (PLS) is a standard statistical method in chemometrics. It can be considered as an incomplete, or “partial”, version of the Least Squares…”
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Dense-Core Plaques in Tg2576 and PSAPP Mouse Models of Alzheimer's Disease Are Centered on Vessel Walls by Kumar-Singh, Samir, Pirici, Daniel, McGowan, Eileen, Serneels, Sally, Ceuterick, Chantal, Hardy, John, Duff, Karen, Dickson, Dennis, Van Broeckhoven, Christine

“…Occurrence of amyloid β (Aβ) dense-core plaques in the brain is one of the chief hallmarks of Alzheimer's disease (AD). It is not yet clear what factors are…”
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Proximate causes of land-use change in Narok District, Kenya: a spatial statistical model by Serneels, Suzanne, Lambin, Eric F

“…This study attempts to identify how much understanding of the driving forces of land-use changes can be gained through a spatial, statistical analysis. Hereto,…”
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Genetic risk and transcriptional variability of amyloid precursor protein in Alzheimer's disease by Brouwers, Nathalie, Sleegers, Kristel, Engelborghs, Sebastiaan, Bogaerts, Veerle, Serneels, Sally, Kamali, Kenan, Corsmit, Ellen, Leenheir, Evelyn De, Martin, Jean-Jacques, De Deyn, Peter P., Broeckhoven, Christine Van, Theuns, Jessie

“…It is well established that Alzheimer's disease causing mutations in APP, PSEN1 and PSEN2 lead to a relative increased production of Aβ42, thereby fostering…”
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Pathogenic APP mutations near the γ-secretase cleavage site differentially affect Aβ secretion and APP C-terminal fragment stability by DE JONGHE, Chris, ESSELENS, Cary, KUMAR-SINGH, Samir, CRAESSAERTS, Katleen, SERNEELS, Sally, CHECLER, Frédéric, ANNAERT, Wim, VAN BROECKHOVEN, Christine, DE STROOPER, Bart

“…Release of amyloid beta (A beta ) from the amyloid precursor protein (APP) requires cleavages by beta - and gamma -secretases and plays a crucial role in…”
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Impact of land-use changes on the wildebeest migration in the northern part of the Serengeti-Mara ecosystem by Serneels, Suzanne, Lambin, Eric F.

“…Aim The study tests the hypothesis that land-use changes in Narok District have had an impact on the wildebeest population [Connochaetes taurinus mearnsi…”
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Spatial Sign Preprocessing:  A Simple Way To Impart Moderate Robustness to Multivariate Estimators by Serneels, Sven, De Nolf, Evert, Van Espen, Pierre J

“…The spatial sign is a multivariate extension of the concept of sign. Recently multivariate estimators of covariance structures based on spatial signs have been…”
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Robust continuum regression by Serneels, Sven, Filzmoser, Peter, Croux, Christophe, Van Espen, Pierre J.

“…Several applications of continuum regression (CR) to non-contaminated data have shown that a significant improvement in predictive power can be obtained…”
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