Search Results - "SEREBRINSKY, G"

Gastrointestinal involvement in Fabry disease. So important, yet often neglected by Politei, J., Thurberg, B.L., Wallace, E., Warnock, D., Serebrinsky, G., Durand, C., Schenone, A.B.

“…Fabry disease is an X‐linked metabolic storage disorder due to the deficiency of lysosomal alpha‐galactosidase A which causes accumulation of…”
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Late onset variants in Fabry disease: Results in high risk population screenings in Argentina by Serebrinsky, G., Calvo, M., Fernandez, S., Saito, S., Ohno, K., Wallace, E., Warnock, D., Sakuraba, H., Politei, J.

“…Screening for Fabry disease (FD) in high risk populations yields a significant number of individuals with novel, ultra rare genetic variants in the GLA gene,…”
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Neutrophil cytotoxicity induced by immune complexes prepared with cationized antibodies by Geffner, J R, Trevani, A S, Malchiodi, E, Serebrinsky, G P, Isturiz, M A

“…Here we analyse the ability of soluble immune complexes (IC) prepared with cationized antibodies to induce cytotoxic responses mediated by neutrophils. While…”
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Neutrophil-mediated cytotoxicity triggered by immune complexes: the role of reactive oxygen metabolites by GEFFNER, J. R, GIORDANO, M, PALERMO, M. S, PRAT, A, SEREBRINSKY, G. P, ISTURIZ, M. A

“…Normal human neutrophils triggered by precipitating immune complexes (IC), soluble IC (sIC) or heat-aggregated IgG (HAIgG) displayed low levels of cytotoxicity…”
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Signal transduction during antibody-dependent cellular cytotoxicity mediated by U937 cells by Serebrinsky, G P, Isturiz, M A

“…Stimulation of the human promonocytic cell line U937 with antibody-coated chicken red blood cells (Ab-CRBC), leads to inositol phosphate (IP) release in the…”
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The role of reactive oxygen intermediates in nonspecific monocyte cytotoxicity induced by immune complexes by GEFFNER, J. R, GIORDANO, M, SEREBRINSKY, G, ISTURIZ, M

“…Normal human monocytes were induced to lyse nonsensitized target cells when triggered by precipitating immune complexes (IC) or soluble heat-aggregated IgG…”
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Different activation pathways involved in antibody-dependent and immune-complexes-triggered cytotoxicity mediated by neutrophils by GEFFNER, J. R, GIORDANO, M, SEREBRINSKY, G, ISTURIZ, M. A

“…We have shown previously that normal human neutrophils triggered by immune complexes displayed significant levels of cytotoxicity towards non-sensitized target…”
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Effect of rheumatoid factors and normal human sera on immune complex-Fc gamma R interaction by Isturiz, M A, Giordano, M, Serebrinsky, G P

“…The results of this study demonstrate that inhibition of antibody-dependent cell-mediated cytotoxicity (ADCC) of human peripheral blood mononuclear cells…”
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Cyclophosphamide augments ADCC by increasing the expression of Fc-receptors by Palermo, M S, Giordano, M, Serebrinsky, G P, Geffner, J R, Ballart, I, Isturiz, M A

“…Previous reports demonstrated that cyclophosphamide (Cy) enhances two Fc gamma receptor (Fc gamma R) mediated functions: antibody-dependent cellular…”
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Reversal of antibody-dependent cellular cytotoxicity suppression by cycloheximide by SEREBRINSKY, G, ISTURIZ, M. A

“…Antibody-dependent cell-mediated cytotoxicity (ADCC) carried out by fresh and precultured peripheral blood mononuclear cells (PBMC) was compared. The results…”
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Gene symbol: GLA. Disease: Fabry disease by Serebrinsky, Graciela Patricia, Pascucelli, Verónica, Politei, Juan Manuel

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Inhibition of lymphocyte and monocyte antibody-dependent cellular cytotoxicity by immune complexes: effect of normal human serum by Geffner, J R, Giordano, M, Serebrinsky, G P, Palermo, M S, Isturiz, M A

“…Antibody-dependent cellular cytotoxicity (ADCC) mediated by peripheral blood mononuclear cells (PBMC) and by isolated populations of lymphocytes and monocytes…”
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Cyclophosphamide modulates arachidonic acid metabolism by peritoneal macrophages by Giordano, M, Geffner, J R, Prat, A, Palermo, M S, Serebrinsky, G P, Isturiz, M A

“…The treatment of mice with a single dose of cyclophosphamide (Cy) (200 mg/kg) enhanced the chemiluminescence (CL) response of peritoneal macrophages (PM)…”
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Genotypic antiretroviral-resistance-analysis in HIV-1 positive patients with treatment failure from Argentina by Benetucci, J, Petroni, A, Illescas, E, Deluchi, G, Serebrinsky, G, Garberi, J

“…The emergence of drug-resistant HIV-1 mutants is one of the major factors that lead to treatment failure (TF). HTV-1 genotypic studies in patients with TF are…”
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Role of complement in the functional recovery of IgG receptors blocked by immune complexes by Isturiz, M A, Geffner, J R, Giordano, M, Serebrinsky, G P, Palermo, M S

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Effect of proteolytic enzymes on neutrophil FcγRII activity by TREVANI, A. S, ANDONEGUI, G. A, ISTURIZ, M. A, SCHATNER, M, SEREBRINSKY, G, GEFFNER, J. R

“…Previous studies have demonstrated that the treatment of neutrophils with proteolytic enzymes markedly reduces the expression of receptor III for the Fc…”
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Effect of rheumatoid factors and normal human sera on immune complex-FeγR interaction by ISTURIZ, M. A, GIORDANO, M, SEREBRINSKY, G. P

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Normal human serum restores the expression of Fcγ receptors in immune complex-blocked human mononuclear cells by GEFFNER, J. R, SEREBRINSKY, G, ISTURIZ, M. A

“…A progressive inhibition of both antibody-dependent cellular cytotoxicity (ADCC) and Fc gamma R expression was observed when peripheral blood mononuclear cells…”
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Interaction of immune complexes and their leukocyte receptors: regulation by the complement system and by cyclophosphamide by Isturiz, M A, Giordano, M, Geffner, J R, Palermo, M S, Serebrinsky, G

“…During the course of this investigation we have studied different aspects related to the interaction between immune complexes (CI) and their cellular receptors…”
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Different requirements for the induction of antibody-dependent and immune complexes triggered cytotoxicity mediated by monocytes by Giordano, M, Geffner, J R, Serebrinsky, G P, Palermo, M S, Isturiz, M A

“…We have previously shown that immune complexes triggered nonspecific cytotoxicity (NSC) towards nonsensitized target cells and antibody-dependent cellular…”
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