Search Results - "SEONG WHO KIM"

Epigenetic regulation of p62/SQSTM1 overcomes the radioresistance of head and neck cancer cells via autophagy-dependent senescence induction by Lee, Myungjin, Nam, Hae Yun, Kang, Hee-Bum, Lee, Won Hyeok, Lee, Geun-Hee, Sung, Gi-Jun, Han, Myung Woul, Cho, Kyung-Ja, Chang, Eun-Ju, Choi, Kyung-Chul, Kim, Seong Who, Kim, Sang Yoon

“…Tumors are composed of subpopulations of cancer cells with functionally distinct features. Intratumoral heterogeneity limits the therapeutic effectiveness of…”
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Metronomic chemotherapy using orally active carboplatin/deoxycholate complex to maintain drug concentration within a tolerable range for effective cancer management by Mahmud, Foyez, Chung, Seung Woo, Alam, Farzana, Choi, Jeong Uk, Kim, Seong Who, Kim, In-San, Kim, Sang Yoon, Lee, Dong Soo, Byun, Youngro

“…Metronomic chemotherapy has translated into favorable toxicity profile and capable of delaying tumor progression. Despite its promise, conventional injectable…”
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Highly efficient genome editing via CRISPR-Cas9 ribonucleoprotein (RNP) delivery in mesenchymal stem cells by A Reum Han, Ha Rim Shin, Jiyeon Kweon, Soo Been Lee, Sang Eun Lee, Eun-young Kim, Eun-ju Chang, Yongsub Kim, Seong Who Kim

“…The CRISPR-Cas9 system has significantly advanced regenerative medicine research by enabling genome editing in stem cells. Due to their desirable properties,…”
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Integrative analysis of microRNA-mediated mitochondrial dysfunction in hippocampal neural progenitor cell death in relation with Alzheimer’s disease by A Reum Han, Tae Kwon Moon, Im Kyeung Kang, Dae Bong Yu, Yechan Kim, Cheolhwan Byon, Sujeong Park, Hae Lin Kim, Kyoung Jin Lee, Heuiran Lee, Ha-na Woo, Seong Who Kim

“…Adult hippocampal neurogenesis plays a pivotal role in maintaining cognitive brain function. However, this process diminishes with age, particularly in…”
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Identification of Far Upstream Element-binding Protein-1 as an Authentic Parkin Substrate by Ko, Han Seok, Kim, Seong Who, Sriram, Sathya R., Dawson, Valina L., Dawson, Ted M.

“…Aminoacyl-tRNA synthetase-interacting multifunctional protein type 2 was recently identified as an authentic substrate of the ubiquitin E3 ligase, parkin, a…”
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Rosiglitazone reduces tau phosphorylation via JNK inhibition in the hippocampus of rats with type 2 diabetes and tau transfected SH-SY5Y cells by Yoon, Seung-Yong, Park, Jeong-Su, Choi, Jung-Eun, Choi, Jin-Myung, Lee, Woo-Je, Kim, Seong-Who, Kim, Dong-Hou

“…Abstract Increasing evidence supports an association between Alzheimer's disease (AD) and diabetes. Rosiglitazone, a peroxisome proliferator-activated…”
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Comparative analysis of human mesenchymal stem cells from bone marrow, adipose tissue, and umbilical cord blood as sources of cell therapy by Jin, Hye Jin, Bae, Yun Kyung, Kim, Miyeon, Kwon, Soon-Jae, Jeon, Hong Bae, Choi, Soo Jin, Kim, Seong Who, Yang, Yoon Sun, Oh, Wonil, Chang, Jong Wook

“…Various source-derived mesenchymal stem cells (MSCs) have been considered for cell therapeutics in incurable diseases. To characterize MSCs from different…”
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Links between accelerated replicative cellular senescence and down-regulation of SPHK1 transcription by Kim, Min Kyung, Lee, Wooseong, Yoon, Gang-Ho, Chang, Eun-Ju, Choi, Sun-Cheol, Kim, Seong Who

“…We have identified a mechanism to diminish the proliferative capacity of cells during cell expansion using human adipose-derived stromal cells (hAD-SCs) as a…”
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Branched-chain amino acids sustain pancreatic cancer growth by regulating lipid metabolism by Lee, Ji Hyeon, Cho, Young-ra, Kim, Ji Hye, Kim, Jongwook, Nam, Hae Yun, Kim, Seong Who, Son, Jaekyoung

“…Branched-chain amino acid (BCAA) catabolism and high levels of enzymes in the BCAA metabolic pathway have recently been shown to be associated with cancer…”
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miR-140-5p suppresses BMP2-mediated osteogenesis in undifferentiated human mesenchymal stem cells by Hwang, Supyong, Park, Seul-Ki, Lee, Ha Yeon, Kim, Seong Who, Lee, Jung Shin, Choi, Eun Kyung, You, Dalsan, Kim, Choung-Soo, Suh, Nayoung

“…•miR-140-5p is commonly enriched in undifferentiated hMSCs from various origins.•miR-140-5p is dynamically expressed during osteogenic…”
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p53/BNIP3-dependent mitophagy limits glycolytic shift in radioresistant cancer by Chang, Hyo Won, Kim, Mi Ra, Lee, Hyang Ju, Lee, Hye Min, Kim, Gui Chul, Lee, Yoon Sun, Nam, Hae Yun, Lee, Myungjin, Jang, Hye Jin, Lee, Kyung Eun, Lee, Jong Cheol, Byun, Youngro, Kim, Seong Who, Kim, Sang Yoon

“…The role of p53 in genotoxic therapy-induced metabolic shift in cancers is not yet known. In this study, we investigated the role of p53 in the glycolytic…”
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Endothelial dysfunction induces atherosclerosis: increased aggrecan expression promotes apoptosis in vascular smooth muscle cells by Kim, Sang-Min, Huh, Jae-Wan, Kim, Eun-Young, Shin, Min-Kyung, Park, Ji-Eun, Kim, Seong Who, Lee, Wooseong, Choi, Bongkun, Chang, Eun-Ju

“…Endothelial dysfunction-induced lipid retention is an early feature of atherosclerotic lesion formation. Apoptosis of vascular smooth muscle cells (VSMCs) is…”
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Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells by Ha, Shinwon, Jeong, Seol-Hwa, Yi, Kyungrim, Chung, Kyung Min, Hong, Caroline Jeeyeon, Kim, Seong Who, Kim, Eun-Kyoung, Yu, Seong-Woon

“…In the adult brain, programmed death of neural stem cells is considered to be critical for tissue homeostasis and cognitive function and is dysregulated in…”
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miR-3189-targeted GLUT3 repression by HDAC2 knockdown inhibits glioblastoma tumorigenesis through regulating glucose metabolism and proliferation by Kwak, Sungmin, Park, Seung-Ho, Kim, Sung-Hak, Sung, Gi-Jun, Song, Ji-Hye, Jeong, Ji-Hoon, Kim, Hyunhee, Ha, Chang Hoon, Kim, Seong Who, Choi, Kyung-Chul

“…Epigenetic regulations frequently appear in Glioblastoma (GBM) and are highly associated with metabolic alterations. Especially, Histone deacetylases (HDACs)…”
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Highly efficient genome editing via CRISPR-Cas9 ribonucleoprotein (RNP) delivery in mesenchymal stem cells by Han, A Reum, Shin, Ha Rim, Kweon, Jiyeon, Lee, Soo Been, Lee, Sang Eun, Kim, Eun-Young, Chang, Eun-Ju, Kim, Yongsub, Kim, Seong Who

“…The CRISPR-Cas9 system has significantly advanced regenerative medicine research by enabling genome editing in stem cells. Due to their desirable properties,…”
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Mesenchymal stem cells protect against the tissue fibrosis of ketamine-induced cystitis in rat bladder by Kim, Aram, Yu, Hwan Yeul, Heo, Jinbeom, Song, Miho, Shin, Jung-Hyun, Lim, Jisun, Yoon, Soo-Jung, Kim, YongHwan, Lee, Seungun, Kim, Seong Who, Oh, Wonil, Choi, Soo Jin, Shin, Dong-Myung, Choo, Myung-Soo

“…Abuse of the hallucinogenic drug ketamine promotes the development of lower urinary tract symptoms that resemble interstitial cystitis. The pathophysiology of…”
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Mesenchymal stem cells prevent the progression of diabetic nephropathy by improving mitochondrial function in tubular epithelial cells by Lee, Seung Eun, Jang, Jung Eun, Kim, Hyun Sik, Jung, Min Kyo, Ko, Myoung Seok, Kim, Mi-Ok, Park, Hye Sun, Oh, Wonil, Choi, Soo Jin, Jin, Hye Jin, Kim, Sang-Yeob, Kim, Yun Jae, Kim, Seong Who, Kim, Min Kyung, Sung, Chang Ohk, Pack, Chan-Gi, Lee, Ki-Up, Koh, Eun Hee

“…The administration of mesenchymal stem cells (MSCs) was shown to attenuate overt as well as early diabetic nephropathy in rodents, but the underlying mechanism…”
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The paracrine effects of mesenchymal stem cells stimulate the regeneration capacity of endogenous stem cells in the repair of a bladder-outlet-obstruction-induced overactive bladder by Song, Miho, Heo, Jinbeom, Chun, Ji-Youn, Bae, Hee Sook, Kang, Jeong Wook, Kang, Hyunsook, Cho, Yong Mee, Kim, Seong Who, Shin, Dong-Myung, Choo, Myung-Soo

“…Overactive bladder (OAB), which is characterized by the sudden and uncomfortable need to urinate with or without urinary leakage, is a challenging urological…”
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Elevated Neuropeptide Y in Endothelial Dysfunction Promotes Macrophage Infiltration and Smooth Muscle Foam Cell Formation by Choi, Bongkun, Shin, Min-Kyung, Kim, Eun-Young, Park, Ji-Eun, Lee, Halim, Kim, Seong Who, Song, Jae-Kwan, Chang, Eun-Ju

“…Endothelial dysfunction has been linked to vascular inflammation and foam cell formation but the underlying mechanisms still remain unclear. We sought to…”
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ZBTB7A suppresses glioblastoma tumorigenesis through the transcriptional repression of EPB41L5 by Jeong, Ji-Hoon, Park, Seung-Ho, Kim, Hyunhee, Nam, Hae Yun, Kim, Sung-Hak, Jeong, Minseok, Kong, Min-Jeong, Son, Jihyun, Jeong, Ji-Eun, Song, Ji-Hye, Kim, Seong Who, Choi, Kyung-Chul

“…Glioblastoma multiforme (GBM), the most aggressive and malignant glioma, has a poor prognosis. Although patients with GBM are treated with surgery,…”
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