Search Results - "SEO, Takayuki"

Efficacy and Safety of Diclofenac–Hyaluronate Conjugate (Diclofenac Etalhyaluronate) for Knee Osteoarthritis: A Randomized Phase III Trial in Japan by Nishida, Yoshihiro, Kano, Kazuyuki, Nobuoka, Yuji, Seo, Takayuki

“…Objective To confirm the efficacy and safety of intraarticular (IA) injection of diclofenac covalently linked to hyaluronic acid (diclofenac etalhyaluronate…”
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Sustained-release diclofenac conjugated to hyaluronate (diclofenac etalhyaluronate) for knee osteoarthritis: a randomized phase 2 study by Nishida, Yoshihiro, Kano, Kazuyuki, Nobuoka, Yuji, Seo, Takayuki

“…Abstract Objective To evaluate the efficacy and safety of diclofenac etalhyaluronate (DF-HA) (ONO-5704/SI-613), a novel DF-conjugated hyaluronate, in patients…”
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Condoliase chemonucleolysis for lumbar disc herniation: A post-hoc follow-up study of patients in previous clinical trials by Matsuyama, Yukihiro, Seo, Takayuki, Chiba, Kazuhiro

“…Chemonucleolysis with condoliase significantly improved clinical symptoms in patients with lumbar disc herniation. We evaluated the surgical intervention rate…”
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Open-label phase 3 study of diclofenac conjugated to hyaluronate (diclofenac etalhyaluronate: ONO-5704/SI-613) for treatment of osteoarthritis: 1-year follow-up by Nishida, Yoshihiro, Kano, Kazuyuki, Osato, Taiki, Seo, Takayuki

“…We evaluated the 1-year safety and efficacy of diclofenac etalhyaluronate (DF-HA), a diclofenac-conjugated hyaluronate, in patients with osteoarthritis (OA)…”
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Diclofenac-hyaluronate conjugate (diclofenac etalhyaluronate) intra-articular injection for hip, ankle, shoulder, and elbow osteoarthritis: a randomized controlled trial by Kubo, Toshikazu, Kumai, Tsukasa, Ikegami, Hiroyasu, Kano, Kazuyuki, Nishii, Megumi, Seo, Takayuki

“…To evaluate the efficacy and safety of intra-articular injection of diclofenac etalhyaluronate (DF-HA) in patients with osteoarthritis (OA) of the hip, ankle,…”
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Association between SCN1A polymorphism and carbamazepine‐resistant epilepsy by Abe, Tomohide, Seo, Takayuki, Ishitsu, Takateru, Nakagawa, Takehiro, Hori, Masaharu, Nakagawa, Kazuko

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • The SCN1A gene encodes the α subunit of the neuronal voltage‐gated sodium channel, which is a target for…”
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A Pooled Analysis of Two Multicenter, Randomized Controlled Trials of a Single Intra-articular Injection of Gel-200 for Treatment of Osteoarthritis of the Knee by Takamura, Junko, Seo, Takayuki, Strand, Vibeke

“…Background and Objective: To perform an integrated analysis of 2 randomized controlled trials (RCTs) to assess the efficacy and safety of a single…”
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Population Estimation Regarding the Effects of Cytochrome P450 2C19 and 3A5 Polymorphisms on Zonisamide Clearance by OKADA, Yusuke, SEO, Takayuki, ISHITSU, Takateru, WANIBUCHI, Atsuko, HASHIMOTO, Nami, HIGA, Yoko, NAKAGAWA, Kazuko

“…We aimed to evaluate the effects of cytochrome P450 (CYP) 2C19 and CYP3A5 polymorphisms on zonisamide (ZNS) clearance. The pharmacokinetics of the 282 ZNS…”
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Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in japanese by GOTO, Shuji, SEO, Takayuki, MURATA, Tsukasa, NAKADA, Naoyuki, UEDA, Nao, ISHITSU, Takateru, NAKAGAWA, Kazuko

“…A nonlinear mixed-effect modeling (NONMEM) program was used to evaluate the effects of cytochrome P450 (CYP) 2C9 and CYP2C19 polymorphisms on the phenobarbital…”
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Association between cytochrome P450 3A5 polymorphism and the lung function in Saskatchewan grain workers by Seo, Takayuki, Pahwa, Punam, McDuffie, Helen H, Yurube, Keigo, Egoshi, Masayoshi, Umemoto, Yuichiro, Ghosh, Sunita, Fukushima, Yumi, Nakagawa, Kazuko

“…OBJECTIVEThe activity of the enzymes that metabolize tobacco smoke may affect the susceptibility to chronic obstructive pulmonary disease (COPD). Cytochrome…”
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Interactive Effect of Paraoxonase-1 Q192R Polymorphism and Smoking History on the Lung Function Decline in Grain Workers by Seo, Takayuki, MS, Pahwa, Punam, PhD, McDuffie, Helen H., PhD, Nakada, Naoyuki, MS, Goto, Shuji, MS, Ghosh, Sunita, MS, Nakagawa, Kazuko, MD, PhD

“…Purpose This retrospective longitudinal study investigated the association between the Q192R polymorphism of the high-density lipoprotein–associated…”
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Impact of CYP2D610 on H1 -antihistamine -induced hypersomnia by SARUWATARI, Junji, MATSUNAGA, Masayuki, IKEDA, Kazuyuki, NAKAO, Masashi, ONIKI, Kentaro, SEO, Takayuki, MIHARA, Shuichi, MARUBAYASHI, Toru, KAMATAKI, Tetsuya, NAKAGAWA, Kazuko

“…This study investigated the relevance of the cytochrome P450 (CYP) 2D6 genotype to the adverse drug reactions (ADRs) of H1-antihistamines and the level of…”
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Condoliase for the Treatment of Lumbar Disc Herniation: A Randomized Controlled Trial by Chiba, Kazuhiro, Matsuyama, Yukihiro, Seo, Takayuki, Toyama, Yoshiaki

“…STUDY DESIGN.A randomized, double-blind, placebo-controlled, multicenter phase III clinical trial. OBJECTIVE.To evaluate the efficacy and safety of…”
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Potential relationships between transaminase abnormality and valproic acid clearance or serum carnitine concentrations in Japanese epileptic patients by Goto, Shuji, Seo, Takayuki, Hagiwara, Takashi, Ueda, Kentaro, Yamauchi, Tsuyuko, Nagata, Shiro, Ando, Yukio, Ishitsu, Takateru, Nakagawa, Kazuko

“…This study tested the hypothesis that the determinants of mild liver injury are prerequisites for more severe idiosyncratic hepatotoxicity. This study verified…”
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A multicenter, randomized, double-blind, dose-finding study of condoliase in patients with lumbar disc herniation by Matsuyama, Yukihiro, Chiba, Kazuhiro, Iwata, Hisashi, Seo, Takayuki, Toyama, Yoshiaki

“…OBJECTIVE Chemonucleolysis with condoliase has the potential to be a new, less invasive therapeutic option for patients with lumbar disc herniation (LDH). The…”
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Association between paraoxonase-1 Q192R polymorphism and lung function among Saskatchewan grain handlers by Takayuki, Seo, Pahwa, Punam, McDuffie, Helen H, Shindo, Junichi, Goto, Shuji, Hashimoto, Mirai, Ghosh, Sunita, Nakagawa, Kazuko

“…Paraoxonase-1 (PON1) is a high-density, lipoprotein-associated, multifunctional antioxidant enzyme that is detected in nonciliated bronchiolar epithelial…”
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Reply by Nishida, Yoshihiro, Kano, Kazuyuki, Nobuoka, Yuji, Seo, Takayuki

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Reply by Nishida, Yoshihiro, Kano, Kazuyuki, Nobuoka, Yuji, Seo, Takayuki

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Reply by Nishida, Yoshihiro, Kano, Kazuyuki, Nobuoka, Yuji, Seo, Takayuki

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Reply by Nishida, Yoshihiro, Kano, Kazuyuki, Nobuoka, Yuji, Seo, Takayuki

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