Search Results - "SENTHIL KUMAR VENUGOPAL"
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Augmenter of liver regeneration: A key protein in liver regeneration and pathophysiology
Published in Hepatology research (01-07-2018)“…Liver is constantly exposed to pathogens, viruses, chemicals, and toxins, and several of them cause injury, leading to the loss of liver mass and sometimes…”
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C-reactive protein decreases prostacyclin release from human aortic endothelial cells
Published in Circulation (New York, N.Y.) (07-10-2003)“…In addition to being a risk marker for cardiovascular disease, much recent data suggest that C-reactive protein (CRP) promotes atherogenesis. Decreased…”
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3
Biocidal activity of Ba2+-doped CeO2 NPs against Streptococcus mutans and Staphylococcus aureus bacterial strains
Published in RSC advances (15-09-2021)“…Mishandling of antibiotics often leads to the development of multiple drug resistance (MDR) among microbes, resulting in the failure of infection treatments…”
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Glibenclamide, ATP and metformin increases the expression of human bile salt export pump ABCB11 [version 1; peer review: 1 approved, 2 approved with reservations]
Published in F1000 research (2020)“…Background: Bile salt export pump (BSEP/ABCB11) is important in the maintenance of the enterohepatic circulation of bile acids and drugs. Drugs such as…”
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Cloning of human ABCB11 gene in E. coli required the removal of an intragenic Pribnow-Schaller Box before it's Insertion into genomic safe harbor AAVS1 site using CRISPR-Cas9 [version 1; peer review: 2 approved]
Published in F1000 research (2020)“…Background: Genomic safe harbors are sites in the genome which are safe for gene insertion such that the inserted gene will function properly, and the…”
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Anticancer potential of NF-κB targeting apoptotic molecule “flavipin” isolated from endophytic Chaetomium globosum
Published in Phytomedicine (Stuttgart) (01-08-2019)“…Anticancer compounds from natural sources have drawn attention due to their structural diversity and relatively lesser side effects. Endophytic fungi are one…”
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Cinnamaldehyde inhibits Enterococcus faecalis biofilm formation and promotes clearance of its colonization by modulation of phagocytes in vitro
Published in Microbial pathogenesis (01-08-2023)“…The nosocomial pathogen, Enterococcus faecalis plays a crucial role in the pathogenesis of variety of infections including endocarditis, urinary tract, and…”
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TGF-β induces liver fibrosis via miRNA-181a-mediated down regulation of augmenter of liver regeneration in hepatic stellate cells
Published in PloS one (05-06-2019)“…To study the role of miRNA-181a and augmenter of liver regeneration in TGF-β-induced fibrosis in hepatic stellate cells. LX2 cells were treated with 20 ng/ml…”
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Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells
Published in Circulation (New York, N.Y.) (17-09-2002)“…C-reactive protein (CRP), the prototypic marker of inflammation, has been shown to be an independent predictor of cardiovascular events. Endothelial nitric…”
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Hepatitis B virus induces cell proliferation via HBx-induced microRNA-21 in hepatocellular carcinoma by targeting programmed cell death protein4 (PDCD4) and phosphatase and tensin homologue (PTEN)
Published in PloS one (14-03-2014)“…Hepatitis B viral infection-induced hepatocellular carcinoma is one of the major problems in the developing countries. One of the HBV proteins, HBx, modulates…”
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Inhibitory potential of EGCG on Streptococcus mutans biofilm: A new approach to prevent Cariogenesis
Published in Microbial pathogenesis (01-06-2020)“…Dental caries is a common cause for tooth loss and Streptococcus mutans is identified as the etiologic pathogen. This study evaluates the inhibitory potential…”
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Macrophage Conditioned Medium Induces the Expression of C-Reactive Protein in Human Aortic Endothelial Cells: Potential for Paracrine/Autocrine Effects
Published in The American journal of pathology (01-04-2005)“…C-reactive protein (CRP) is a risk marker for cardiovascular events in apparently healthy persons. Cogent data show that, aside from the liver, CRP is produced…”
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13
Synergistic Antibacterial Effect of the Magnesium-Doped ZnO Nanoparticles with Chloramphenicol
Published in BioNanoScience (01-03-2020)“…Emergence of drug resistance in bacteria for an array of antibiotics has created a demand for the discovery of novel drugs. In this study, we mixed the…”
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Hepatitis B Virus X Protein Inhibits the Expression of Barrier To Autointegration factor1 via Upregulating miR-203 Expression in Hepatic Cells
Published in Microbiology spectrum (14-02-2023)“…Hepatitis B virus (HBV) infection targets host restriction factors that inhibit its replication and survival. Previous studies have shown that barriers to…”
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Effect of C-reactive protein on vascular cells: evidence for a proinflammatory, proatherogenic role
Published in Current opinion in nephrology and hypertension (01-01-2005)“…PURPOSE OF REVIEWC-reactive protein (CRP) is the prototypic downstream marker of inflammation. High levels of CRP predict future cardiovascular risk in…”
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α-Tocopherol Decreases Superoxide Anion Release in Human Monocytes Under Hyperglycemic Conditions Via Inhibition of Protein Kinase C-α
Published in Diabetes (New York, N.Y.) (01-10-2002)“…α-Tocopherol Decreases Superoxide Anion Release in Human Monocytes Under Hyperglycemic Conditions Via Inhibition of Protein Kinase C-α Senthil Kumar Venugopal…”
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RRR-α-tocopherol decreases the expression of the major scavenger receptor, CD36, in human macrophages via inhibition of tyrosine kinase (Tyk2)
Published in Atherosclerosis (01-08-2004)“…The class B scavenger receptor, CD36, binds to oxidized LDL (OxLDL), is present in atherosclerotic lesions, and is upregulated by OxLDL or AcLDL. Previously we…”
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Macrophage Conditioned Medium Induces the Expression of C-Reactive Protein in Human Aortic Endothelial Cells
Published in The American journal of pathology (01-04-2005)“…C-reactive protein (CRP) is a risk marker for cardiovascular events in apparently healthy persons. Cogent data show that, aside from the liver, CRP is produced…”
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Journal Article -
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Biocidal (bacterial and cancer cells) activities of chitosan/CuO nanomaterial, synthesized via a green process
Published in Carbohydrate polymers (01-05-2021)“…[Display omitted] •Eco-friendly multifunctional CCuO NM was synthesized via the green process.•Copper salt was nucleated with Psidium Guajava leaves extract to…”
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Global microRNA expression profiling in the liver biopsies of hepatitis B virus–infected patients suggests specific microRNA signatures for viral persistence and hepatocellular injury
Published in Hepatology (Baltimore, Md.) (01-05-2018)“…Hepatitis B virus (HBV) can manipulate the microRNA (miRNA) regulatory networks in infected cells to create a permissive environment for viral replication,…”
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