Search Results - "SELNER, Milada"
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Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells
Published in Molecular pharmacology (01-11-2001)“…CEM-ARAC leukemia cells with resistance to cytarabine were shown to lack equilibrative transporter (hENT1) expression and activity. Stable transfer of hCNT2…”
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Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines
Published in Cancer research (Chicago, Ill.) (01-10-1998)“…Gemcitabine (2',2'-difluorodeoxycytidine) is a novel pyrimidine nucleoside drug with clinical efficacy in several common epithelial cancers. We have proposed…”
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Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines
Published in Cancer research (Chicago, Ill.) (01-10-2001)“…Troxacitabine (Troxatyl; BCH-4556; (-)-2'-deoxy-3'-oxacytidine), a deoxycytidine analogue with an unusual dioxolane structure and nonnatural L-configuration,…”
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4
Differential activity of vincristine and vinblastine against cultured cells
Published in Cancer research (Chicago, Ill.) (01-08-1984)“…Vincristine and vinblastine exhibit differential activity against tumors and normal tissues. In this work, a number of cultured cell lines were assayed for…”
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Effect of lithium on the myelosuppressive and chemotherapeutic activities of vinblastine
Published in Cancer research (Chicago, Ill.) (01-03-1981)“…Serum concentrations of lithium after i.p. administration to normal mice declined with biphasic kinetics. Treatment of mice bearing ascitic L1210 leukemia with…”
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