Search Results - "SELEJAN, Simina"

Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation by Zewinger, Stephen, Reiser, Jochen, Jankowski, Vera, Alansary, Dalia, Hahm, Eunsil, Triem, Sarah, Klug, Mira, Schunk, Stefan J., Schmit, David, Kramann, Rafael, Körbel, Christina, Ampofo, Emmanuel, Laschke, Matthias W., Selejan, Simina-Ramona, Paschen, Anna, Herter, Tobias, Schuster, Susanne, Silbernagel, Günther, Sester, Martina, Sester, Urban, Aßmann, Gunter, Bals, Robert, Kostner, Gerhard, Jahnen-Dechent, Willi, Menger, Michael D., Rohrer, Lucia, März, Winfried, Böhm, Michael, Jankowski, Joachim, Kopf, Manfred, Latz, Eicke, Niemeyer, Barbara A., Fliser, Danilo, Laufs, Ulrich, Speer, Thimoteus

“…NLRP3-inflammasome-driven inflammation is involved in the pathogenesis of a variety of diseases. Identification of endogenous inflammasome activators is…”
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Glycyrrhizin through liquorice intake modulates ACE2 and HMGB1 levels—A pilot study in healthy individuals with implications for COVID-19 and ARDS by Buder, Felix, Selejan, Simina-Ramona, Hohl, Mathias, Kindermann, Michael, Herr, Christian, Lepper, Philipp M, Bals, Robert, Salzberger, Bernd, Mahfoud, Felix, Böhm, Michael

“…Background Glycyrrhizin, an active component of liquorice root extract, exhibits antiviral and immunomodulatory properties by direct inhibition of the…”
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Post-infarction cardiac remodeling—differential biomarkers for left atrial and left ventricular remodeling by Selejan, Simina-Ramona, Hohl, Mathias, Böhm, Michael

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Therapeutic approaches in heart failure with preserved ejection fraction: past, present, and future by Wintrich, Jan, Kindermann, Ingrid, Ukena, Christian, Selejan, Simina, Werner, Christian, Maack, Christoph, Laufs, Ulrich, Tschöpe, Carsten, Anker, Stefan D., Lam, Carolyn S. P., Voors, Adriaan A., Böhm, Michael

“…In contrast to the wealth of proven therapies for heart failure with reduced ejection fraction (HFrEF), therapeutic efforts in the past have failed to improve…”
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Renal Denervation Prevents Atrial Arrhythmogenic Substrate Development in CKD by Hohl, Mathias, Selejan, Simina-Ramona, Wintrich, Jan, Lehnert, Ulrike, Speer, Thimoteus, Schneider, Clara, Mauz, Muriel, Markwirth, Philipp, Wong, Dickson W.L., Boor, Peter, Kazakov, Andrey, Mollenhauer, Martin, Linz, Benedikt, Klinkhammer, Barbara Mara, Hübner, Ulrich, Ukena, Christian, Moellmann, Julia, Lehrke, Michael, Wagenpfeil, Stefan, Werner, Christian, Linz, Dominik, Mahfoud, Felix, Böhm, Michael

“…In patients with chronic kidney disease (CKD), atrial fibrillation (AF) is highly prevalent and represents a major risk factor for stroke and death. CKD is…”
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Renal denervation reduces atrial remodeling in hypertensive rats with metabolic syndrome by Selejan, Simina-Ramona, Linz, Dominik, Mauz, Muriel, Hohl, Mathias, Huynh, Anh Khoa Dennis, Speer, Thimoteus, Wintrich, Jan, Kazakov, Andrey, Werner, Christian, Mahfoud, Felix, Böhm, Michael

“…Atrial fibrillation (AF) is highly prevalent in hypertensive patients with metabolic syndrome and is related to inflammation and activation of the…”
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Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice by Hohl, Mathias, Mayr, Manuel, Lang, Lisa, Nickel, Alexander G., Barallobre-Barreiro, Javier, Yin, Xiaoke, Speer, Thimoteus, Selejan, Simina-Ramona, Goettsch, Claudia, Erb, Katharina, Fecher-Trost, Claudia, Reil, Jan-Christian, Linz, Benedikt, Ruf, Sven, Hübschle, Thomas, Maack, Christoph, Böhm, Michael, Sadowski, Thorsten, Linz, Dominik

“…In the heart, the serine carboxypeptidase cathepsin A (CatA) is distributed between lysosomes and the extracellular matrix (ECM). CatA-mediated degradation of…”
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Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form by Zewinger, Stephen, Reiser, Jochen, Jankowski, Vera, Alansary, Dalia, Hahm, Eunsil, Triem, Sarah, Klug, Mira, Schunk, Stefan J., Schmit, David, Kramann, Rafael, Körbel, Christina, Ampofo, Emmanuel, Laschke, Matthias W., Selejan, Simina-Ramona, Paschen, Anna, Herter, Tobias, Gaul, Susanne, Silbernagel, Günther, Sester, Martina, Sester, Urban, Aßmann, Gunter, Bals, Robert, Kostner, Gerhard, Jahnen-Dechent, Willi, Menger, Michael D., Rohrer, Lucia, März, Winfried, Böhm, Michael, Jankowski, Joachim, Kopf, Manfred, Latz, Eicke, Niemeyer, Barbara A., Fliser, Danilo, Laufs, Ulrich, Speer, Thimoteus

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Suppressed MMP-9 Activity in Myocardial Infarction-Related Cardiogenic Shock Implies Diminished Rage Degradation by Selejan, Simina-Ramona, Hewera, Lisa, Hohl, Matthias, Kazakov, Andrey, Ewen, Sebastian, Kindermann, Ingrid, Böhm, Michael, Link, Andreas

“…BACKGROUND:Receptor for advanced glycation end products (RAGE) and its cleavage fragment soluble RAGE (sRAGE) are opposite players in inflammation. Enhanced…”
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Circulating angiopoietins and cardiovascular mortality in cardiogenic shock by Link, Andreas, Pöss, Janine, Rbah, Ranja, Barth, Christine, Feth, Luisa, Selejan, Simina, Böhm, Michael

“…Vascular integrity is disturbed in shock contributing to clinical appearance and serious outcomes. While angiopoietin (Ang)-1 protects from vascular…”
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Sympathoadrenergic suppression improves heart function by upregulating the ratio of sRAGE/RAGE in hypertension with metabolic syndrome by Selejan, Simina-Ramona, Linz, Dominik, Tatu, Anna-Maria, Hohl, Mathias, Speer, Thimoteus, Ewen, Sebastian, Mahfoud, Felix, Kindermann, Ingrid, Zamyatkin, Olesja, Kazakov, Andrey, Laufs, Ulrich, Böhm, Michael

“…Receptors-for-Advanced-Glycation-End-products (RAGE) activate pro-inflammatory programs mediated by carboxymethyllysine (CML) and high-mobility-group-box1…”
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Argatroban for anticoagulation in continuous renal replacement therapy by LINK, Andreas, GIRNDT, Matthias, SELEJAN, Simina, MATHES, Alexander, BÖHM, Michael, RENSING, Hauke

“…Argatroban, a direct thrombin inhibitor, was evaluated for anticoagulation in continuous renal replacement therapy (CRRT) in critically ill patients with…”
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Role of receptor for advanced glycation end products in cardiogenic shock by Selejan, Simina-Ramona, Pöss, Janine, Hewera, Lisa, Kazakov, Andrey, Böhm, Michael, Link, Andreas

“…OBJECTIVES:Activation of the receptor for advanced glycation end products by its ligands promotes inflammatory processes and tissue injury. The available…”
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Myopathic Cardiac Genotypes Increase Risk for Myocarditis by Kontorovich, Amy R, Patel, Nihir, Moscati, Arden, Richter, Felix, Peter, Inga, Purevjav, Enkhsaikhan, Selejan, Simina Ramona, Kindermann, Ingrid, Towbin, Jeffrey A, Bohm, Michael, Klingel, Karin, Gelb, Bruce D

“…Impairments in certain cardiac genes confer risk for myocarditis in children. To determine the extent of this association, we performed genomic sequencing in…”
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Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease by Wollenhaupt, Julia, Frisch, Janina, Harlacher, Eva, Wong, Dickson W.L., Jin, Han, Schulte, Corinna, Vondenhoff, Sonja, Moellmann, Julia, Klinkhammer, Barbara Mara, Zhang, Li, Baleanu-Curaj, Adelina, Liehn, Elisa A., Speer, Thimoteus, Kazakov, Andrey, Werner, Christian, van der Vorst, Emiel P.C., Selejan, Simina-Ramona, Hohl, Mathias, Böhm, Michael, Kramann, Rafael, Biessen, Erik A.L., Lehrke, Michael, Marx, Nikolaus, Jankowski, Joachim, Maack, Christoph, Boor, Peter, Prates Roma, Leticia, Noels, Heidi

“…Patients with chronic kidney disease (CKD) have an increased risk of cardiovascular events and exhibit myocardial changes including left ventricular (LV)…”
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Aldosterone promotes atrial fibrillation by REIL, Jan-Christian, HOHL, Mathias, ALLESSIE, Maurits A, BÖHM, Michael, NEUBERGER, Hans-Ruprecht, SELEJAN, Simina, LIPP, Peter, DRAUTZ, Fabian, KAZAKOW, Andrey, MÜNZ, Benedikt M, MÜLLER, Patrick, STEENDIJK, Paul, REIL, Gert-Hinrich

“…Hyperaldosteronism is associated with an increased prevalence of atrial fibrillation (AF). However, it is unclear whether this is the consequence of altered…”
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Renal Denervation Prevents Atrial Arrhythmogenic Substrate Development in CKD by Hohl, Mathias, Selejan, Simina-Ramona, Wintrich, Jan, Lehnert, Ulrike, Speer, Thimoteus, Schneider, Clara, Mauz, Muriel, Markwirth, Philipp, Wong, Dickson W.L., Boor, Peter, Kazakov, Andrey, Mollenhauer, Martin, Linz, Benedikt, Klinkhammer, Barbara Mara, Hübner, Ulrich, Ukena, Christian, Moellmann, Julia, Lehrke, Michael, Wagenpfeil, Stefan, Werner, Christian, Linz, Dominik, Mahfoud, Felix, Böhm, Michael

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Proenkephalin A 119-159 (penKid) and mortality in stable patients at high cardiovascular risk by Rau, Matthias, Kurt, Berkan, Hartmann, Oliver, Lobo de Sá, Fábia Daniela, Schwarz, Marvin, Thiele, Kirsten, Hartmann, Niels-Ulrik Korbinian, Spiesshoefer, Jens, Möllmann, Julia, Hohl, Mathias, Selejan, Simina-Ramona, van der Vorst, Emiel P C, Dahl, Edgar, Marx, Nikolaus, Kahles, Florian, Lehrke, Michael

“…Background Proenkephalin A 119–159 (penKid) is a novel blood biomarker for real-time assessment of kidney function and was found to be independently associated…”
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Rosuvastatin induces apoptosis in CD4(+)CD28 (null) T cells in patients with acute coronary syndromes by Link, Andreas, Selejan, Simina, Hewera, Lisa, Walter, Felix, Nickenig, Georg, Böhm, Michael

“…CD4(+)CD28(null) cells represent an aggressive and long-living T cell subpopulation, capable of infiltrating atheromatous plaque, leading to destabilisation…”
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Telmisartan in high-risk patients intolerant of ACE inhibitors by Link, Andreas, Reil, Jan Christian, Selejan, Simina

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