Search Results - "SEKINE, I"

Emerging ethnic differences in lung cancer therapy by Sekine, I, Yamamoto, N, Nishio, K, Saijo, N

“…Although global clinical trials for lung cancer can enable the development of new agents efficiently, whether the results of clinical trials performed in one…”
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Changes in tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma after GnRH agonist therapy by Khan, Khaleque Newaz, Kitajima, Michio, Hiraki, Koichi, Fujishita, Akira, Sekine, Ichiro, Ishimaru, Tadayuki, Masuzaki, Hideaki

“…BACKGROUND Information is limited regarding the multifunctional role of GnRH agonist (GnRHa) therapy in reproductive diseases. We investigated the pattern of…”
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Diagnosis and treatment of bone metastasis: comprehensive guideline of the Japanese Society of Medical Oncology, Japanese Orthopedic Association, Japanese Urological Association, and Japanese Society for Radiation Oncology by Shibata, H, Kato, S, Sekine, I, Abe, K, Araki, N, Iguchi, H, Izumi, T, Inaba, Y, Osaka, I, Kato, S, Kawai, A, Kinuya, S, Kodaira, M, Kobayashi, E, Kobayashi, T, Sato, J, Shinohara, N, Takahashi, S, Takamatsu, Y, Takayama, K, Takayama, K, Tateishi, U, Nagakura, H, Hosaka, M, Morioka, H, Moriya, T, Yuasa, T, Yurikusa, T, Yomiya, K, Yoshida, M

“…Diagnosis and treatment of bone metastasis requires various types of measures, specialists and caregivers. To provide better diagnosis and treatment, a…”
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Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors by Kusaba, T, Nakayama, T, Yamazumi, K, Yakata, Y, Yoshizaki, A, Nagayasu, T, Sekine, I

“…Background: The signal transducer and activator of transcription 3 (STAT3) is a key signalling molecule implicated in the regulation of growth and malignant…”
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Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions by Okamoto, S, Jiang, Y, Kawamura, K, Shingyoji, M, Tada, Y, Sekine, I, Takiguchi, Y, Tatsumi, K, Kobayashi, H, Shimada, H, Hiroshima, K, Tagawa, M

“…Zoledronic acid (ZOL), a nitrogen-containing bisphosphonate, produced anti-tumor effects through apoptosis induction or S-phase arrest depending on human…”
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A phase II dose-ranging study of palonosetron in Japanese patients receiving moderately emetogenic chemotherapy, including anthracycline and cyclophosphamide-based chemotherapy by Segawa, Y., Aogi, K., Inoue, K., Sano, M., Sekine, I., Tokuda, Y., Isobe, H., Ogura, T., Tsuboi, M., Atagi, S.

“…Background: The 5-HT3 receptor antagonists (RAs) help maintain the standard of care, in various combinations with other agents, for prevention of…”
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Expression of p53 synergistically augments caspases-mediated apoptosis induced by replication-competent adenoviruses in pancreatic carcinoma cells by Takei, Y, Okamoto, S, Kawamura, K, Jiang, Y, Morinaga, T, Shingyoji, M, Sekine, I, Kubo, S, Tada, Y, Tatsumi, K, Shimada, H, Hiroshima, K, Yamaguchi, N, Tagawa, M

“…We examined cytotoxicity of replication-competent type 5 adenoviruses (Ad5) in human pancreatic carcinoma cells with a p53 -defective genotype. The…”
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Circulating endothelial cells in Kawasaki disease by NAKATANI, K., TAKESHITA, S., TSUJIMOTO, H., KAWAMURA, Y., TOKUTOMI, T., SEKINE, I.

“…summary Recent reports have demonstrated that circulating endothelial cells (CECs) are observed in several diseases with vascular injury. Because Kawasaki…”
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Toll-like receptor 4-mediated growth of endometriosis by human heat-shock protein 70 by Khan, Khaleque Newaz, Kitajima, Michio, Imamura, Takehito, Hiraki, Koichi, Fujishita, Akira, Sekine, Ichiro, Ishimaru, Tadayuki, Masuzaki, Hideaki

“…BACKGROUND We investigated the role of human heat-shock protein 70 (Hsp70) in Toll-like receptor 4 (TLR4)-mediated growth of endometriosis. METHODS TLR4…”
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A phase II study of palonosetron combined with dexamethasone to prevent nausea and vomiting induced by highly emetogenic chemotherapy by Maemondo, M., Masuda, N., Sekine, I., Kubota, K., Segawa, Y., Shibuya, M., Imamura, F., Katakami, N., Hida, T., Takeo, S.

“…Background: This is a randomized, double-blind, dose-ranging study in patients receiving highly emetogenic chemotherapy (HEC) to evaluate the safety, efficacy,…”
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Incidence, risk factors and treatment outcomes of extravasation of cytotoxic agents in an outpatient chemotherapy clinic by Sakaida, Emiko, Sekine, Ikuo, Iwasawa, Shunichiro, Kurimoto, Ryota, Uehara, Takashi, Ooka, Yoshihiko, Akanuma, Naoki, Tada, Yuji, Imai, Chiaki, Oku, Tomoko, Takiguchi, Yuichi

“…Extravasation, the accidental leakage of an anticancer agent from a vessel into the surrounding tissues, can lead to irreversible local injuries and severe…”
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Corrosion inhibition of mild steel by schiff base compounds in various aqueous solutions: part 1 by Shokry, H, Yuasa, M, Sekine, I, Issa, R.M, El-baradie, H.Y, Gomma, G.K

“…The corrosion inhibition by Schiff base compounds derived from diamines and o-hydroxy, o-methoxy aromatic aldehydes was investigated by weight loss,…”
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TTMPP-Catalyzed Addition of Alkynes Using Trimethylsilylacetylenes by Matsukawa, S., Sekine, I.

“…A highly basic phosphine, tris(2,4,6-trimethoxyphenyl)phosphine (TTMPP), catalyzes alkynylation using trimethylsilylalkyne to give the corresponding products…”
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Characteristics and outcomes of patients with advanced non-small-cell lung cancer who declined to participate in randomised clinical chemotherapy trials by Tanai, C, Nokihara, H, Yamamoto, S, Kunitoh, H, Yamamoto, N, Sekine, I, Ohe, Y, Tamura, T

“…There are inadequate data on the outcomes of patients who declined to participate in randomised clinical trials as compared with those of participants. We…”
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Overexpression of Ets-1 proto-oncogene in latent and clinical prostatic carcinomas by Alipov, G, Nakayama, T, Ito, M, Kawai, K, Naito, S, Nakashima, M, Niino, D, Sekine, I

“…Aims : The high incidence of clinically diagnosed prostatic cancer is exceeded by the frequency of tumours detected at autopsy. The Ets‐1 proto‐oncogene is…”
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Quality of life and disease-related symptoms in previously treated Japanese patients with non-small-cell lung cancer: results of a randomized phase III study (V-15-32) of gefitinib versus docetaxel by Sekine, I., Ichinose, Y., Nishiwaki, Y., Yamamoto, N., Tsuboi, M., Nakagawa, K., Shinkai, T., Negoro, S., Imamura, F., Eguchi, K., Takeda, K., Itoh, Y., Tamura, T., Saijo, N., Fukuoka, M.

“…This report describes quality of life (QoL) findings of a randomized study comparing gefitinib with docetaxel in patients with advanced/metastatic pretreated…”
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Expression of human β-defensin 2 (hBD-2) in Helicobacter pylori induced gastritis: antibacterial effect of hBD-2 against Helicobacter pylori by HAMANAKA, Y, NAKASHIMA, M, WADA, A, ITO, M, KURAZONO, H, HOJO, H, NAKAHARA, Y, KOHNO, S, HIRAYAMA, T, SEKINE, I

“…Human beta-defensin 2 (hBD-2) plays a role in the innate defence system at mucosal surfaces. Colonisation of Helicobacter pylori in the stomach is an important…”
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9060 POSTER Phase I Trial of Pemetrexed and Cisplatin Combination Chemotherapy With Concurrent Thoracic Radiotherapy in Japanese Patients With Locally Advanced Non-Small-Cell Lung Cancer by Sekine, I, Kubota, K, Niho, S, Sumi, M, Nihei, K, Sekiguchi, R, Funai, J, Enatsu, S, Ohe, Y, Tamura, T

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9120 POSTER Linifanib Plus Carboplatin/Paclitaxel (CP) in Japanese Patients With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) -Phase 1 Preliminary Results by Ohvanaqi, F, Horai, T, Nishio, M, Sekine, I, Yamamoto, N, Nakagawa, K, Okamoto, I, Terashima, M, Li, X, Tamura, T

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Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia by IWAI, T, YOKOTA, S, SEKINE, I, MUGISHIMA, H, NISHIMURA, Y, KOIZUMI, S, HORIKOSHI, Y, MIMAYA, J, OHTA, S, NISHIKAWA, K, IWAI, A, SHIMOKAWA, T, NAKAO, M, NAKAYAMA, M, KAWAKAMI, K, GUSHIKEN, T, HYAKUNA, N, KATANO, N, TSURUSAWA, M, FUJIMOTO, T, OKAMOTO, T, TANIWAKI, M, ONODERA, N, WATANABE, A, KIKUTA, A, TANAKA, A, ASAMI, K

“…We analyzed tandem duplication in the juxtamembrane (JM) domain of the FLT3 (FMS-like tyrosine kinase 3/FLK2, CD135) gene in 94 children with acute myeloid…”
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