Search Results - "SEHY, David"

A novel microfluidic microplate as the next generation assay platform for enzyme linked immunoassays (ELISA) by Kai, Junhai, Puntambekar, Aniruddha, Santiago, Nelson, Lee, Se Hwan, Sehy, David W, Moore, Victor, Han, Jungyoup, Ahn, Chong H

“…In this work we introduce a novel microfluidic enzyme linked immunoassays (ELISA) microplate as the next generation assay platform for unparalleled assay…”
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IL-6 Promotes NK Cell Production of IL-17 during Toxoplasmosis by Passos, Sara T, Silver, Jonathan S, O'Hara, Aisling C, Sehy, David, Stumhofer, Jason S, Hunter, Christopher A

“…Previous studies have implicated T cell production of IL-17 in resistance to Toxoplasma gondii as well as the development of immune-mediated pathology during…”
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The in vivo cytokine capture assay for measurement of cytokine production in the mouse by Finkelman, Fred, Morris, Suzanne, Orekhova, Tatyana, Sehy, David

“…Because most cytokines are utilized, catabolized, or excreted shortly after they are produced, it has been difficult to directly measure in vivo cytokine…”
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The inhibitory cytokine IL-35 contributes to regulatory T-cell function by COLLISON, Lauren W, WORKMAN, Creg J, KUO, Timothy T, BOYD, Kelli, YAO WANG, VIGNALI, Kate M, CROSS, Richard, SEHY, David, BLUMBERG, Richard S, VIGNALI, Dario A. A

“…Regulatory T (T(reg)) cells are a critical sub-population of CD4+ T cells that are essential for maintaining self tolerance and preventing autoimmunity, for…”
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Comparison of Membrane-bound and Secreted TGFβ by IL-2 Activated Natural and Adaptive CD4+CD25+ Regulatory Cells from Healthy and Lupus-prone Mice by Zheng, Song Guo, Assistant Professor of Research Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, Wang, Julie, Research Lab Specialist, University of Southern California Keck School of Medicine, Los Angeles, CA, Ye, Shuang, Postdoctoraltoral Fellow, University of Southern California Keck School of Medicine, Los Angeles, CA, Sehy, David, Director, New Technologies, eBioscience/Department of New Technologies, San Diego, CA, Palian, Beth, Postdoctoraltoral Student, University of Southern California Keck School of Medicine, Los Angeles, CA, Horwitz, David A., Professor Chief, Division of Rheumatology and Immunology, University of Southern California Keck School of Medicine, Los Angeles, CA

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Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system by Hunter, Christopher A, Stumhofer, Jason S, Laurence, Arian, Wilson, Emma H, Huang, Elaine, Tato, Cristina M, Johnson, Leanne M, Villarino, Alejandro V, Huang, Qiulong, Yoshimura, Akihiko, Sehy, David, Saris, Christiaan J M, O'Shea, John J, Hennighausen, Lothar, Ernst, Matthias

“…Studies have focused on the events that influence the development of interleukin 17 (IL-17)-producing T helper cells (T(H)-17 cells) associated with…”
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Optimiser™ Microplate enables simultaneous multi-analyte quantitation using ultra-low sample volumes in a 2-hour assay: Validation of a Novel 10-Analyte Th17 Cell Panel (124.7) by Kai, Junhai, Moore, Victor, Puntambekar, Aniruddha, Sehy, David, Lakkis, Montaha, Lee, Sean, Han, Jungyoup, Ahn, Chong

“…Abstract Optimiser™ Microfluidic ELISA Plates combine microfluidics with 96-well architecture to offer dramatic improvements over conventional ELISA, such as…”
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Optimiser™ microfluidics ELISA plates overcome confounding rheumatoid factor-like and HAMA-like false positive effects in immunoassay detection of IL-17A in serum matrices. (65.35) by Sehy, David, Kai, Junhai, Santiago, Nelson, Puntambekar, Aniruddha, Lee, Se Hwan, Durnell, Randy, Schultheis, Ron, Han, Jungyoup, Ahn, Chong

“…Abstract The measurement of analytes in serum matrices by sandwich ELISA can be confounded by naturally-occurring interfering factors which can cross link…”
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Optimiser™ microplate and OptiMax™ reagent systems enable femtogram/ml level sensitivity employing standard ELISA equipment and protocols (65.32) by Kai, Junhai, Santiago, Nelson, Puntambekar, Aniruddha, Lee, Se Hwan, Sehy, David, Durnell, Randy, Schultheis, Ron, Han, Jungyoup, Ahn, Chong

“…Abstract Optimiser™ Microfluidic ELISA Plates dramatically enhance ELISA sensitivity through the incorporation of microfluidic channels into a standard ELISA…”
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Development of functionally active recombinant form of mouse IL-35 (57.11) by Lee, Hyun-Ku, Pascual, David, Sehy, David, Chitta, Sriram, Singh, Gita, Quintel, Payton, Andrew, Kody, Wardle, Lauren, Rosenberg, Jonathan, Singh, Sujay

“…Abstract As a novel heterodimeric cytokine and one of the IL-12 family members, IL-35 is composed of IL-12p35 subunit and Epstein-Barr virus-induced gene 3…”
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IL-6 promotes NK cell production of IL-17 during toxoplasmosis1 by Passos, Sara T., Silver, Jonathan S., O'Hara, Aisling C., Sehy, David, Stumhofer, Jason S., Hunter, Christopher A.

“…Previous studies have implicated T cell production of IL-17 in resistance to T. gondii as well as the development of immune mediated pathology during this…”
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Blockade of TLR9 agonist-induced type I interferons promotes inflammatory cytokine IFN-γ and IL-17 secretion by activated human PBMC by Meyers, John A., Mangini, Alyson J., Nagai, Taro, Roff, Calvin F., Sehy, David, van Seventer, Gijs A., van Seventer, Jean Maguire

“…Type I interferons (IFN) (IFN-α/β) are recognized as both inhibitors and effectors of autoimmune disease. In multiple sclerosis, IFN-β therapy appears…”
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The inhibitory cytokine IL-35 contributes to regulatory T-cell function by Collison, Lauren W, Workman, Creg J, Kuo, Timothy T, Boyd, Kelli, Wang, Yao, Vignali, Kate M, Cross, Richard, Sehy, David, Vignali, Dario A.A

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IL-35 and regulatory T cell function by Vignali, Dario A.A., Collison, Lauren W., Workman, Creg J., Kuo, Timothy T., Boyd, Kelli, Wang, Yao, Vignali, Kate M., Cross, Richard, Sehy, David, Blumberg, Richard S., Henderson, Abigail L., Chaturvedi, Vandana, Turk, Mary J.

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A novel dye that facilitates three-color analysis of PBMC by flow cytometry by Shih, C C, Bolton, G, Sehy, D, Lay, G, Campbell, D, Huang, C M

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Sensitivity of committed hematopoietic progenitor cells in vitro (BFU-E, CFU-E, CFU-GM) and two human carcinoma cell lines toward rhodamine-123 and phosphonium salt II-41 by Sehy, D W, Shao, L E, Rideout, D, Yu, J

“…Lipophilic cationic compounds accumulate more rapidly in the mitochondria of many carcinoma-derived cells than in non-transformed cells, thus leading to their…”
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