Search Results - "SEARS, M."

Potential Therapeutic Targets for Cisplatin-Induced Kidney Injury: Lessons from Other Models of AKI and Fibrosis by Sears, Sophia M, Siskind, Leah J

“…The effectiveness of cisplatin, a mainstay in the treatment of many solid organ cancers, is hindered by dose-limiting nephrotoxicity. Cisplatin causes AKI in…”
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Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study by Azad, MB, Konya, T, Persaud, RR, Guttman, DS, Chari, RS, Field, CJ, Sears, MR, Mandhane, PJ, Turvey, SE, Subbarao, P, Becker, AB, Scott, JA, Kozyrskyj, AL, Allen, R, Anand, SS, Befus, AD, Brauer, M, Brook, JR, Chen, E, Cyr, M, Daley, D, Dell, S, Denburg, JA, Elliott, S, Grasemann, H, HayGlass, K, Hegele, R, Holness, DL, Lou, WYW, Kobor, MS, Kollman, TR, Laprise, C, Larché, M, Macri, J, Mandhane, PM, Miller, G, Moqbel, R, Moraes, T, Paré, PD, Ramsey, C, Ratjen, F, Sandford, A, Scott, J, Silverman, F, Takaro, T, Tang, P, Tebbutt, S, To, T

“…Objective Dysbiosis of the infant gut microbiota may have long‐term health consequences. This study aimed to determine the impact of maternal intrapartum…”
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Diverse cellular functions of barrier-to-autointegration factor and its roles in disease by Sears, Rhiannon M, Roux, Kyle J

“…Barrier-to-autointegration factor (BAF; encoded by ) is a small highly conserved, ubiquitous and self-associating protein that coordinates with numerous…”
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BioID as a Tool for Protein-Proximity Labeling in Living Cells by Sears, Rhiannon M, May, Danielle G, Roux, Kyle J

“…BioID has become an increasingly utilized tool for identifying candidate protein-protein interactions (PPIs) in living cells. This method utilizes a…”
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Ni-Catalyzed Regioselective 1,2-Dicarbofunctionalization of Olefins by Intercepting Heck Intermediates as Imine-Stabilized Transient Metallacycles by Shrestha, Bijay, Basnet, Prakash, Dhungana, Roshan K, KC, Shekhar, Thapa, Surendra, Sears, Jeremiah M, Giri, Ramesh

“…We disclose a strategy for Ni-catalyzed dicarbofunctionalization of olefins in styrenes by intercepting Heck C­(sp3)–NiX intermediates with arylzinc reagents…”
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Active avoidance requires a serial basal amygdala to nucleus accumbens shell circuit by Ramirez, Franchesca, Moscarello, Justin M, LeDoux, Joseph E, Sears, Robert M

“…Freezing is a species-typical defensive reaction to conditioned threats. While the neural circuitry of aversive Pavlovian behavior has been extensively…”
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Repair of nuclear ruptures requires barrier-to-autointegration factor by Halfmann, Charles T, Sears, Rhiannon M, Katiyar, Aditya, Busselman, Brook W, Aman, London K, Zhang, Qiao, O'Bryan, Christopher S, Angelini, Thomas E, Lele, Tanmay P, Roux, Kyle J

“…Cell nuclei rupture following exposure to mechanical force and/or upon weakening of nuclear integrity, but nuclear ruptures are repairable…”
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Interpersonal autonomic synchrony and sexual satisfaction: A preliminary examination by Freihart, B., Sears, M., Meston, C.

“…Introduction A growing body of literature has increased our understanding of interpersonal autonomic synchrony (IAS), or exchanges across biological systems…”
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Infant gut microbiota and food sensitization: associations in the first year of life by Azad, M. B., Konya, T., Guttman, D. S., Field, C. J., Sears, M. R., HayGlass, K. T., Mandhane, P. J., Turvey, S. E., Subbarao, P., Becker, A. B., Scott, J. A., Kozyrskyj, A. L.

“…Summary Background The gut microbiota is established during infancy and plays a fundamental role in shaping host immunity. Colonization patterns may influence…”
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Real-time observation of laser-driven electron acceleration by Buck, Alexander, Veisz, Laszlo, Nicolai, Maria, Schmid, Karl, Sears, Chris M. S, Sävert, Alexander, Mikhailova, Julia M, Krausz, Ferenc, Kaluza, Malte C

“…Electron acceleration by laser-driven plasma waves is capableof producing ultra-relativistic, quasi-monoenergetic electron bunches with orders of magnitude…”
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Type I collagen as an extracellular matrix for the in vitro growth of human small intestinal epithelium by Jabaji, Ziyad, Brinkley, Garrett J, Khalil, Hassan A, Sears, Connie M, Lei, Nan Ye, Lewis, Michael, Stelzner, Matthias, Martín, Martín G, Dunn, James C Y

“…We previously reported in vitro maintenance and proliferation of human small intestinal epithelium using Matrigel, a proprietary basement membrane product…”
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Asthma exacerbations · 1: Epidemiology by Johnston, N W, Sears, M R

“…Asthma exacerbations may be triggered by a number of atmospheric and domiciliary environmental factors as well as by those encountered in schools and…”
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Orexin/hypocretin system modulates amygdala-dependent threat learning through the locus coeruleus by Sears, Robert M., Fink, Ann E., Wigestrand, Mattis B., Farb, Claudia R., de Lecea, Luis, LeDoux, Joseph E.

“…Survival in a dangerous environment requires learning about stimuli that predict harm. Although recent work has focused on the amygdala as the locus of…”
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Adiponectin, leptin and insulin in breast milk: associations with maternal characteristics and infant body composition in the first year of life by Chan, D, Goruk, S, Becker, A B, Subbarao, P, Mandhane, P J, Turvey, S E, Lefebvre, D, Sears, M R, Field, C J, Azad, M B

“…Background/Objectives: Breastfeeding may protect against excessive weight gain during infancy. However, the breast milk components responsible for this effect…”
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A brainstem-central amygdala circuit underlies defensive responses to learned threats by Gu, Yiran, Piper, Walter T., Branigan, Lauren A., Vazey, Elena M., Aston-Jones, Gary, Lin, Longnian, LeDoux, Joseph E., Sears, Robert M.

“…Norepinephrine (NE) plays a central role in the acquisition of aversive learning via actions in the lateral nucleus of the amygdala (LA) [ 1 , 2 ]. However,…”
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Leptin Receptor Signaling in Midbrain Dopamine Neurons Regulates Feeding by Hommel, Jonathan D., Trinko, Richard, Sears, Robert M., Georgescu, Dan, Liu, Zong-Wu, Gao, Xiao-Bing, Thurmon, Jeremy J., Marinelli, Michela, DiLeone, Ralph J.

“…The leptin hormone is critical for normal food intake and metabolism. While leptin receptor ( Lepr) function has been well studied in the hypothalamus, the…”
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A Multidimensional Evaluation of Intimacy by Sears, M., Mcmahon, L., Crosby, C., Freihart, B., Meston, C.

“…Introduction Supportive, nurturing relationships facilitate good health, well-being, and life satisfaction. Intimacy is crucial for developing successful…”
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Long-acting β-agonists : a review of formoterol safety data from asthma clinical trials by SEARS, M. R, OTTOSSON, A, RADNER, F, SUISSA, S

“…The safety of long-acting beta(2)-agonist (LABA) treatment in asthma has been questioned following reported increased respiratory deaths when salmeterol was…”
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Cognitive Decline and Older Driver Crash Risk by Fraade‐Blanar, Laura A., Ebel, Beth E., Larson, Eric B., Sears, Jeanne M., Thompson, Hilaire J., Chan, Kwun Chuen G., Crane, Paul K.

“…Objectives To examine automobile crash risk associated with cognition in older drivers without dementia. Design Retrospective secondary analysis of…”
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Perceived Conjunctival Foreign Material Egress in Morgellons Disease: A Case Study by Ghiam, Sean, Sojitra, Badal, Reiff, Collin, M. Sears, Connie, N. Karlin, Justin

“…The purpose of this report is to present a case of a 63-year-old man with orbital Morgellons disease. A 63-year-old man presented reporting 15 years of daily…”
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