Search Results - "SEAGAR, M"

Synaptic vesicle chips to assay botulinum neurotoxins by Ferracci, Géraldine, Miquelis, Raymond, Kozaki, Shunji, Seagar, Michael, Lévêque, Christian

“…BoNTs (botulinum neurotoxins), considered to be the most toxic of all biological substances, inhibit neurotransmission through proteolytic cleavage of SNARE…”
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Purification of the N-type calcium channel associated with syntaxin and synaptotagmin. A complex implicated in synaptic vesicle exocytosis by Lévêque, C, el Far, O, Martin-Moutot, N, Sato, K, Kato, R, Takahashi, M, Seagar, M J

“…omega-Conotoxin-sensitive N-type calcium channels control neurotransmitter release at the nerve terminal and interact with proteins implicated in secretion…”
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Ca2+/Calmodulin Transfers the Membrane-Proximal Lipid-Binding Domain of the v-SNARE Synaptobrevin from Cis to Trans Bilayers by de Haro, Luc, Ferracci, Géraldine, Opi, Sandrine, Iborra, Cécile, Quetglas, Stéphanie, Miquelis, Raymond, Lévêque, Christian, Seagar, Michael, Catterall, William A.

“…Soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) protein interactions at the synaptic vesicle/plasma membrane interface…”
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Subunit Structure of Dihydropyridine-Sensitive Calcium Channels from Skeletal Muscle by Takahashi, Masami, Seagar, Michael J., Jones, Jean F., Bernhard F. X. Reber, Catterall, William A.

“…Purified dihydropyridine-sensitive calcium channels from rabbit transverse-tubule membranes consist of three noncovalently associated classes of subunits: α…”
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Cellular localization of synaptotagmin I, II, and III mRNAs in the central nervous system and pituitary and adrenal glands of the rat by Marqueze, B, Boudier, JA, Mizuta, M, Inagaki, N, Seino, S, Seagar, M

“…Three isoforms of synaptotagmin, a synaptic vesicle protein involved in neurotransmitter release, have been characterized in the rat, although functional…”
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Antibodies against the β subunit of voltage-dependent calcium channels in Lambert–Eaton Myasthenic Syndrome by Raymond, C, Walker, D, Bichet, D, Iborra, C, Martin-Moutot, N, Seagar, M, De Waard, M

“…Lambert–Eaton myasthenic syndrome is an autoimmune disease that impairs neuromuscular transmission. Several studies suggest that neurotransmitter release is…”
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Molecular properties of dihydropyridine-sensitive calcium channels in skeletal muscle by Catterall, W A, Seagar, M J, Takahashi, M

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Antigens associated with N- and L-type calcium channels in Lambert-Eaton myasthenic syndrome by el Far, O, Marquèze, B, Leveque, C, Martin-Moutôt, N, Lang, B, Newsom-Davis, J, Yoshida, A, Takahashi, M, Seagar, M J

“…In Lambert-Eaton myasthenic syndrome neurotransmitter release is reduced by an autoimmune response directed against the calcium channel complex of the nerve…”
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Developmental Regulation of Synaptotagmin I, II, III, and IV mRNAs in the Rat CNS by Berton, Frederique, Iborra, Cecile, Boudier, Jeanne-Andree, Seagar, Michael J, Marqueze, Beatrice

“…Synaptotagmin I is an abundant synaptic vesicle protein that has an essential function in mediating Ca2+-triggered neurotransmitter release. We have analyzed…”
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The Synaptic Vesicle Protein Synaptotagmin Associates with Calcium Channels and is a Putative Lambert-Eaton Myasthenic Syndrome Antigen by Leveque, Christian, Hoshino, Toshimitsu, David, Pascale, Shoji-Kasai, Yoko, Leys, Katherine, omori, Akira, Lang, Bethan, El Far, Oussama, Sato, Kazuki, Martin-Moutot, Nicole, Newsom-Davis, John, Takahashi, Masami, Seagar, Michael J.

“…Immunoglobulin G fractions from patients with Lambert-Eaton myasthenic syndrome (LEMS), an autoimmune disease of neuromuscular transmission,…”
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Cysteine String Proteins Associated with Secretory Granules of the Rat Neurohypophysis by Pupier, Sandrine, Leveque, Christian, Marqueze, Beatrice, Kataoka, Masakazu, Takahashi, Masami, Seagar, Michael J

“…The properties and subcellular distribution of cysteine string proteins (csps) were analyzed in peptidergic nerve terminals of the rat neurohypophysis…”
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Role of Thr(11) in the binding of omega-conotoxin MVIIC to N-type Ca2+ channels by Minami, K, Raymond, C, Martin-Moutot, N, Ohtake, A, Van Renterghem, C, Takahashi, M, Seagar, M J, Mori, Y, Sato, K

“…As replacement of Thr(11) of omega-conotoxin MVIIC with Ala significantly reduced the affinity for both N- and P/Q-type calcium channels, we examined the…”
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Mouse motor nerve terminal immunoreactivity to synaptotagmin II during sustained quantal transmitter release by Angaut-Petit, Denise, Juzans, Pascal, Molgó, Jordi, Faille, Lucette, Seagar, Michael J., Takahashi, Masami, Shoji-Kasai, Yoko

“…An antibody directed against the lumenal NH 2-terminus of synaptotagmin II was used to examine the distribution of this vesicular protein either after…”
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Omega-conotoxin sensitive calcium channels in cerebellar granule cells are not coupled to [3H]glutamate release by Grignon, S, Seagar, M J, Couraud, F

“…We have studied the biochemical and functional aspects of omega-conotoxin GVIA (omega-CgTx)-sensitive calcium channels in cerebellar granule cells in vitro…”
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Solubilization of the apamin receptor associated with a calcium- activated potassium channel from rat brain by Seagar, MJ, Marqueze, B, Couraud, F

“…The apamin binding protein was solubilized from rat brain synaptic membranes using sodium cholate. Receptor yield and stability depended closely on the…”
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Interaction of a synaptobrevin (VAMP)-syntaxin complex with presynaptic calcium channels by El Far, Oussama, Charvin, Nathalie, Leveque, Christian, Martin-Moutot, Nicole, Takahashi, Masami, Seagar, Michael J.

“…Nerve terminal protein complexes implicated in exocytosis were examined by immuno-isolation from rat brain synaptosomes. Immunoprecipitation with anti-syntaxin…”
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Protein chip technology for rapid and sensitive detection of botulinum neurotoxin activity by Ferracci, G., Maulet, Y., Mazuet, C., Popoff, M.R., El Far, O., Seagar, M., Lévêque, C.

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Binding of Ala-scanning analogs of ω-conotoxin MVIIC to N- and P/Q-type calcium channels by Sato, Kazuki, Raymond, Cecile, Martin-Moutot, Nicole, Sasaki, Toru, Ohtake, Atsuko, Minami, Kazushi, Van Renterghem, Catherine, Kim, Jae Il, Takahashi, Masami, Seagar, Michael J.

“…ω-Conotoxin MVIIC binds to P/Q-type calcium channels with high affinity and N-type channels with low affinity. To reveal the residues essential for subtype…”
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Binding of Six Chimeric Analogs of ω-Conotoxin MVIIA and MVIIC to N- and P/Q-Type Calcium Channels by Sato, Kazuki, Raymond, Cecile, Martin-Moutot, Nicole, Sasaki, Toru, Ohtake, Atsuko, Minami, Kazushi, Van Renterghem, Catherine, Takahashi, Masami, Seagar, Michael J.

“…Replacement of the N-terminal half of ω-conotoxin MVIIC, a peptide blocker of P/Q-type calcium channels, with that of ω-conotoxin MVIIA significantly increased…”
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Immunological characterization of proteins associated with the purified omega-conotoxin GVIA receptor by McEnery, M W, Snowman, A M, Seagar, M J, Copeland, T D, Takahashi, M

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