Search Results - "SCOFIELD, R. Hal"

Autoimmunity and infection in Sjögrenʼs syndrome by Igoe, Ann, Scofield, R Hal

“…PURPOSE OF REVIEWTo summarize the recent developments concerning the potential viral pathomechanisms and involvement of viruses in Sjögrenʼs syndrome, and to…”
Get full text

Physical Examination - Still Relevant in Sjögren Syndrome by Hal Scofield, R

Get full text

Dietary Strawberries Improve Serum Metabolites of Cardiometabolic Risks in Adults with Features of the Metabolic Syndrome in a Randomized Controlled Crossover Trial by Basu, Arpita, Izuora, Kenneth, Hooyman, Andrew, Scofield, Hal R, Ebersole, Jeffrey L

“…Dietary strawberries have been shown to improve cardiometabolic risks in multiple clinical trials. However, no studies have reported effects on serum…”
Get full text

Western blotting: an introduction by Kurien, Biji T, Scofield, R Hal

“…Western blotting is an important procedure for the immunodetection of proteins, particularly proteins that are of low abundance. This process involves the…”
Get more information

Strawberries Improve Pain and Inflammation in Obese Adults with Radiographic Evidence of Knee Osteoarthritis by Schell, Jace, Scofield, R Hal, Barrett, James R, Kurien, Biji T, Betts, Nancy, Lyons, Timothy J, Zhao, Yan Daniel, Basu, Arpita

“…Osteoarthritis (OA), the most common form of arthritis, is a significant public health burden in U.S. adults. Among its many risk factors, obesity is a key…”
Get full text

Autoimmunity and oxidatively modified autoantigens by Kurien, Biji T, Scofield, R. Hal

“…Abstract Oxidative damage mediated by reactive oxygen species results in the generation of deleterious by-products. The oxidation process itself and the…”
Get full text

The Potential Utility of Salivary and Tear Proteomics to Discriminate Sjögren's Disease from Non-Sjögren's Sicca by George, Christopher T, Kurien, Biji T, Scofield, R Hal

“…Sjögren's Disease (SjD) is an autoimmune disorder associated with decreased saliva and/or tear secretions, resulting in patients reporting dryness in the mouth…”
Get full text

Post traumatic stress disorder associated hypothalamic-pituitary-adrenal axis dysregulation and physical illness by Lawrence, Stephanie, Scofield, R. Hal

“…Conventional human stress responses are mediated by the sympathetic adrenal medullar (SAM) axis and the hypothalamic pituitary adrenal (HPA) axis. The SAM axis…”
Get full text

Development of Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus by Arbuckle, Melissa R, McClain, Micah T, Rubertone, Mark V, Scofield, R. Hal, Dennis, Gregory J, James, Judith A, Harley, John B

“…In 130 military personnel, systemic lupus erythematosus (SLE) developed after blood samples had been stored in the U.S. Department of Defense Serum Repository…”
Get full text

Polygenic autoimmune disease risk alleles impacting B cell tolerance act in concert across shared molecular networks in mouse and in humans by Harley, Isaac T W, Allison, Kristen, Scofield, R Hal

“…Most B cells produced in the bone marrow have some level of autoreactivity. Despite efforts of central tolerance to eliminate these cells, many escape to…”
Get full text

New Treatment Guidelines for Sjögren's Disease by Vivino, Frederick B., MD, MS, Carsons, Steven E., MD, Foulks, Gary, MD, Daniels, Troy E., DDS, MS, Parke, Ann, MD, Brennan, Michael T., DDS, MHS, Forstot, S. Lance, MD, Scofield, R. Hal, MD, Hammitt, Katherine M., MA

“…Sjögren's disease is associated with a high burden of illness, diminished quality of life, and increased health care costs. The Sjögren’s Syndrome Foundation…”
Get full text

P51 First case of lupus: Bishop Eraclius of Liège, Belgium by Thomas, Donald, Hal Scofield, R

“…BackgroundAround 963 A.D., Bishop Eraclius (Liège, Belgium) wrote an affidavit stating, ‘I … was nearly taken to death by the disease called Lupus.’ On the…”
Get full text

Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus by Ritterhouse, Lauren L, Crowe, Sherry R, Niewold, Timothy B, Kamen, Diane L, Macwana, Susan R, Roberts, Virginia C, Dedeke, Amy B, Harley, John B, Scofield, R Hal, Guthridge, Joel M, James, Judith A

“…Vitamin D deficiency is widespread and has been associated with many chronic diseases, including autoimmune disorders. A study was undertaken to explore the…”
Get more information

Strawberries decrease circulating levels of tumor necrosis factor and lipid peroxides in obese adults with knee osteoarthritis by Basu, Arpita, Kurien, Biji T, Tran, Huyen, Byrd, Bre'Ana, Maher, Joey, Schell, Jace, Masek, Emily, Barrett, James R, Lyons, Timothy J, Betts, Nancy M, Hal Scofield, R

“…Knee osteoarthritis (OA) is increasingly prevalent in obese people, who often have high cardio-metabolic risk factors. Among the few available non-surgical…”
Get more information

Dietary Strawberries Improve Cardiometabolic Risks in Adults with Obesity and Elevated Serum LDL Cholesterol in a Randomized Controlled Crossover Trial by Basu, Arpita, Izuora, Kenneth, Betts, Nancy M, Kinney, Jefferson W, Salazar, Arnold M, Ebersole, Jeffrey L, Scofield, R Hal

“…Dietary berries, such as strawberries, are rich in bioactive compounds and have been shown to lower cardiometabolic risk. We examined the effects of two…”
Get full text

Sjögren Syndrome without Focal Lymphocytic Infiltration of the Salivary Glands by Sharma, Rohan, Chaudhari, Kaustubh S, Kurien, Biji T, Grundahl, Kiely, Radfar, Lida, Lewis, David M, Lessard, Christopher J, Li, He, Rasmussen, Astrid, Sivils, Kathy L, Scofield, R Hal

“…Primary Sjögren syndrome (SS) is characterized by a focal lymphocytic infiltrate in exocrine glands. We describe patients who lacked this key feature. We…”
Get full text

Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis by Harris, Valerie M, Koelsch, Kristi A, Kurien, Biji T, Harley, Isaac T W, Wren, Jonathan D, Harley, John B, Scofield, R Hal

“…Ninety percent of systemic lupus erythematosus (SLE) patients are women. X chromosome-dosage increases susceptibility to SLE and primary Sjögren's syndrome…”
Get full text

Previous diagnosis of Sjögren's Syndrome as rheumatoid arthritis or systemic lupus erythematosus by Rasmussen, Astrid, Radfar, Lida, Lewis, David, Grundahl, Kiely, Stone, Donald U, Kaufman, C Erick, Rhodus, Nelson L, Segal, Barbara, Wallace, Daniel J, Weisman, Michael H, Venuturupalli, Swamy, Kurien, Biji T, Lessard, Christopher J, Sivils, Kathy L, Scofield, R Hal

“…The diagnosis of SS is often difficult and many patients are symptomatic for years with other diagnoses before confirmation of SS. Our aim was to determine…”
Get full text

Genetics of systemic lupus erythematosus and Sjögrenʼs syndrome by Scofield, R Hal

“…PURPOSE OF REVIEWTo determine the advances made in the genetics of systemic lupus erythematosus (SLE) or Sjögrenʼs syndrome as the era of genome-wide…”
Get full text

T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation by Bachmann, Michael P, Bartsch, Tabea, Bippes, Claudia C, Bachmann, Dominik, Puentes-Cala, Edinson, Bachmann, Jennifer, Bartsch, Holger, Arndt, Claudia, Koristka, Stefanie, Loureiro, Liliana R, Kegler, Alexandra, Laube, Markus, Gross, Joanne K, Gross, Tim, Kurien, Biji T, Scofield, R Hal, Farris, A Darise, James, Judith A, Schmitz, Marc, Feldmann, Anja

“…Since the first description of nuclear autoantigens in the late 1960s and early 1970s, researchers, including ourselves, have found it difficult to establish…”
Get full text