Search Results - "SCIURBA, Frank C"

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    Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease by Pavord, Ian D, Chanez, Pascal, Criner, Gerard J, Kerstjens, Huib A.M, Korn, Stephanie, Lugogo, Njira, Martinot, Jean-Benoit, Sagara, Hironori, Albers, Frank C, Bradford, Eric S, Harris, Stephanie S, Mayer, Bhabita, Rubin, David B, Yancey, Steven W, Sciurba, Frank C

    Published in The New England journal of medicine (26-10-2017)
    “…In this trial evaluating mepolizumab, an anti–interleukin-5 antibody, the rate of COPD exacerbations among patients whose COPD was characterized by an…”
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    A Randomized Study of Endobronchial Valves for Advanced Emphysema by Sciurba, Frank C, Ernst, Armin, Herth, Felix J.F, Strange, Charlie, Criner, Gerard J, Marquette, Charles H, Kovitz, Kevin L, Chiacchierini, Richard P, Goldin, Jonathan, McLennan, Geoffrey

    Published in The New England journal of medicine (23-09-2010)
    “…One of the characteristics of severe emphysema is hyperinflation of regions of the lungs. In this trial, valves that prevented air entry but allowed air to…”
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    Respiratory symptoms and airway obstruction in HIV-infected subjects in the HAART era by George, M Patricia, Kannass, Mouhamed, Huang, Laurence, Sciurba, Frank C, Morris, Alison

    Published in PloS one (21-07-2009)
    “…Prevalence and risk factors for respiratory symptoms and airway obstruction in HIV-infected subjects in the era of highly active antiretroviral therapy (HAART)…”
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    Identification of factors directly linked to incident chronic obstructive pulmonary disease: A causal graph modeling study by Gregg, Robert W, Karoleski, Chad M, Silverman, Edwin K, Sciurba, Frank C, DeMeo, Dawn L, Benos, Panayiotis V

    Published in PLoS medicine (13-08-2024)
    “…Beyond exposure to cigarette smoking and aging, the factors that influence lung function decline to incident chronic obstructive pulmonary disease (COPD)…”
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    Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease by Chen, Zhi-Hua, Kim, Hong Pyo, Sciurba, Frank C, Lee, Seon-Jin, Feghali-Bostwick, Carol, Stolz, Donna B, Dhir, Rajiv, Landreneau, Rodney J, Schuchert, Mathew J, Yousem, Samuel A, Nakahira, Kiichi, Pilewski, Joseph M, Lee, Janet S, Zhang, Yingze, Ryter, Stefan W, Choi, Augustine M K

    Published in PloS one (02-10-2008)
    “…Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by abnormal cellular responses to cigarette smoke, resulting in tissue…”
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    A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation by Chen, Bill B, Coon, Tiffany A, Glasser, Jennifer R, McVerry, Bryan J, Zhao, Jing, Zhao, Yutong, Zou, Chunbin, Ellis, Bryon, Sciurba, Frank C, Zhang, Yingze, Mallampalli, Rama K

    Published in Nature immunology (01-05-2013)
    “…Inflammation needs to be tightly regulated to avoid immunopathology. Mallampalli and colleagues show that a system of F box proteins tunes proinflammatory…”
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    Optimal threshold in CT quantification of emphysema by Wang, Zhimin, Gu, Suicheng, Leader, Joseph K., Kundu, Shinjini, Tedrow, John R., Sciurba, Frank C., Gur, David, Siegfried, Jill M., Pu, Jiantao

    Published in European radiology (01-04-2013)
    “…Objectives To determine the optimal threshold by quantitatively assessing the extent of emphysema at the level of the entire lung and at the level of…”
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    The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease by Hogg, James C, Chu, Fanny, Utokaparch, Soraya, Woods, Ryan, Elliott, W. Mark, Buzatu, Liliana, Cherniack, Ruben M, Rogers, Robert M, Sciurba, Frank C, Coxson, Harvey O, Paré, Peter D

    Published in The New England journal of medicine (24-06-2004)
    “…Physiological observations indicate that the small airways are the predominant site of airway obstruction in patients with chronic obstructive pulmonary…”
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    Incident low muscle mass is associated with greater lung disease and lower circulating leptin in a tobacco-exposed longitudinal cohort by Zou, Richard H, Nouraie, S Mehdi, Karoleski, Chad, Zhang, Yingze, Sciurba, Frank C, Forman, Daniel E, Bon, Jessica

    Published in Respiratory research (22-09-2023)
    “…Muscle loss is prevalent in chronic obstructive pulmonary disease (COPD). Prior studies evaluating musculoskeletal dysfunction in COPD have focused on…”
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    Cell-free DNA levels associate with COPD exacerbations and mortality by Ware, Sarah A, Kliment, Corrine R, Giordano, Luca, Redding, Kevin M, Rumsey, William L, Bates, Stewart, Zhang, Yingze, Sciurba, Frank C, Nouraie, S Mehdi, Kaufman, Brett A

    Published in Respiratory research (18-01-2024)
    “…Good biological indicators capable of predicting chronic obstructive pulmonary disease (COPD) phenotypes and clinical trajectories are lacking. Because nuclear…”
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    Much lower prevalence and mortality of chronic obstructive pulmonary disease in Japan than in the US despite higher smoking rates: A meta analysis/systematic review by Sekikawa, Akira, Li, Mengyi, Joshi, Niva, Herbert, Brandon, Tilves, Curtis, Cui, Chendi, Gao, Shiyao, Chang, Yuefang, Nakano, Yasutaka, Sciurba, Frank C

    Published in Journal of Epidemiology (2024)
    “…Background: A recent systematic review showed Japan's mortality from chronic obstructive pulmonary disease (COPD) is the lowest among 204 countries, despite…”
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    Interstitial Lung Abnormalities and Reduced Exercise Capacity by DOYLE, Tracy J, WASHKO, George R, HATABU, Hiroto, ROSAS, Ivan O, HUNNINGHAKE, Gary M, FERNANDEZ, Isis E, NISHINO, Mizuki, OKAJIMA, Yuka, YAMASHIRO, Tsuneo, DIVO, Miguel J, CELLI, Bartolome R, SCIURBA, Frank C, SILVERMAN, Edwin K

    “…The relationship between interstitial lung abnormalities (ILA) and exercise capacity has not been comprehensively evaluated. To assess the validity of the…”
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    Radiographic Emphysema Predicts Low Bone Mineral Density in a Tobacco-exposed Cohort by BON, Jessica, FUHRMAN, Carl R, SCIURBA, Frank C, WEISSFELD, Joel L, DUNCAN, Steven R, BRANCH, Robert A, CHANG, Chung-Chou H, YINGZE ZHANG, LEADER, Joseph K, GUR, David, GREENSPAN, Susan L

    “…Studies demonstrating an association between chronic obstructive pulmonary disease and low bone mineral density (BMD) implicate factors distinct from…”
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