Search Results - "SCHWENKENBECHER, PHILIPP"

Common and uncommon neurological manifestations of neuroborreliosis leading to hospitalization by Schwenkenbecher, Philipp, Pul, Refik, Wurster, Ulrich, Conzen, Josef, Pars, Kaweh, Hartmann, Hans, Sühs, Kurt-Wolfram, Sedlacek, Ludwig, Stangel, Martin, Trebst, Corinna, Skripuletz, Thomas

“…Neuroborreliosis represents a relevant infectious disease and can cause a variety of neurological manifestations. Different stages and syndromes are described…”
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Varicella zoster virus infections in neurological patients: a clinical study by Skripuletz, Thomas, Pars, Kaweh, Schulte, Alina, Schwenkenbecher, Philipp, Yildiz, Özlem, Ganzenmueller, Tina, Kuhn, Maike, Spreer, Annette, Wurster, Ulrich, Pul, Refik, Stangel, Martin, Sühs, Kurt-Wolfram, Trebst, Corinna

“…Varicella zoster virus (VZV) reactivation is a common infectious disease in neurology and VZV the second most frequent virus detected in encephalitis. This…”
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The Persisting Significance of Oligoclonal Bands in the Dawning Era of Kappa Free Light Chains for the Diagnosis of Multiple Sclerosis by Schwenkenbecher, Philipp, Konen, Franz Felix, Wurster, Ulrich, Jendretzky, Konstantin Fritz, Gingele, Stefan, Sühs, Kurt-Wolfram, Pul, Refik, Witte, Torsten, Stangel, Martin, Skripuletz, Thomas

“…The latest revision of the McDonald criteria of 2017 considers the evidence of an intrathecal immunoglobulin (IgG) synthesis as a diagnostic criterion for…”
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Impact of the McDonald Criteria 2017 on Early Diagnosis of Relapsing-Remitting Multiple Sclerosis by Schwenkenbecher, Philipp, Wurster, Ulrich, Konen, Franz Felix, Gingele, Stefan, Sühs, Kurt-Wolfram, Wattjes, Mike P, Stangel, Martin, Skripuletz, Thomas

“…Multiple sclerosis is a chronic immune mediated demyelinating disease leading to neurological disabilities that need to be diagnosed and treated early…”
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Clinical and paraclinical characteristics of optic neuritis in the context of the McDonald criteria 2017 by Jendretzky, Konstantin F., Bajor, Anna, Lezius, Lisa-Marie, Hümmert, Martin W., Konen, Franz Felix, Grosse, Gerrit M., Schwenkenbecher, Philipp, Sühs, Kurt-Wolfram, Trebst, Corinna, Framme, Carsten, Wattjes, Mike P., Meuth, Sven G., Gingele, Stefan, Skripuletz, Thomas

“…Optic neuritis is often an initial symptom in multiple sclerosis (MS) or clinically isolated syndrome (CIS), yet comprehensive studies using the 2017 McDonald…”
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Leptomeningeal Metastasis: The Role of Cerebrospinal Fluid Diagnostics by Bönig, Lena, Möhn, Nora, Ahlbrecht, Jonas, Wurster, Ulrich, Raab, Peter, Puppe, Wolfram, Sühs, Kurt-Wolfram, Stangel, Martin, Skripuletz, Thomas, Schwenkenbecher, Philipp

“…Metastatic spread into the cerebrospinal fluid (CSF) represents a severe complication of malignant disease with poor prognosis. Although early diagnosis is…”
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Ocrelizumab Depletes CD20⁺ T Cells in Multiple Sclerosis Patients by Gingele, Stefan, Jacobus, Thais Langer, Konen, Franz Felix, Hümmert, Martin W, Sühs, Kurt-Wolfram, Schwenkenbecher, Philipp, Ahlbrecht, Jonas, Möhn, Nora, Müschen, Lars H, Bönig, Lena, Alvermann, Sascha, Schmidt, Reinhold E, Stangel, Martin, Jacobs, Roland, Skripuletz, Thomas

“…Ocrelizumab, a humanized monoclonal anti-CD20 antibody, has shown pronounced effects in reduction of disease activity in multiple sclerosis (MS) patients and…”
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Fumaric Acids Directly Influence Gene Expression of Neuroprotective Factors in Rodent Microglia by Kronenberg, Jessica, Pars, Kaweh, Brieskorn, Marina, Prajeeth, Chittappen K, Heckers, Sandra, Schwenkenbecher, Philipp, Skripuletz, Thomas, Pul, Refik, Pavlou, Andreas, Stangel, Martin

“…Dimethylfumarate (DMF) has been approved the for treatment of relapsing-remitting multiple sclerosis. The mode of action of DMF and its assumed active primary…”
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Radiotherapy in patients with brain metastases with and without concomitant immunotherapy: comparison of patient outcome and neurotoxicity by Elyan, Natalie, Schwenkenbecher, Philipp, Grote-Levi, Lea, Becker, Jan-Niklas, Merten, Roland, Christiansen, Hans, Skripuletz, Thomas, Steinmann, Diana, Möhn, Nora

“…Background/Aim Recently, immune checkpoint inhibitors (ICI) have been added to the treatment of brain metastases. While combining radiotherapy and ICI can…”
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The Increasing Role of Kappa Free Light Chains in the Diagnosis of Multiple Sclerosis by Konen, Franz Felix, Schwenkenbecher, Philipp, Jendretzky, Konstantin Fritz, Gingele, Stefan, Sühs, Kurt-Wolfram, Tumani, Hayrettin, Süße, Marie, Skripuletz, Thomas

“…Free light chains (FLC) are a promising biomarker to detect intrathecal inflammation in patients with inflammatory central nervous system (CNS) diseases,…”
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Clinically Isolated Syndrome According to McDonald 2010: Intrathecal IgG Synthesis Still Predictive for Conversion to Multiple Sclerosis by Schwenkenbecher, Philipp, Sarikidi, Anastasia, Bönig, Lena, Wurster, Ulrich, Bronzlik, Paul, Sühs, Kurt-Wolfram, Pul, Refik, Stangel, Martin, Skripuletz, Thomas

“…While the revised McDonald criteria of 2010 allow for the diagnosis of multiple sclerosis (MS) in an earlier stage, there is still a need to identify the risk…”
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McDonald Criteria 2010 and 2005 Compared: Persistence of High Oligoclonal Band Prevalence Despite Almost Doubled Diagnostic Sensitivity by Schwenkenbecher, Philipp, Sarikidi, Anastasia, Wurster, Ulrich, Bronzlik, Paul, Sühs, Kurt-Wolfram, Raab, Peter, Stangel, Martin, Pul, Refik, Skripuletz, Thomas

“…The 2010 McDonald criteria were developed to allow a more rapid diagnosis of relapsing-remitting multiple sclerosis (MS) by only one MRI of the brain. Although…”
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The Influence of Blood Contamination on Cerebrospinal Fluid Diagnostics by Schwenkenbecher, Philipp, Janssen, Theda, Wurster, Ulrich, Konen, Felix Franz, Neyazi, Alexandra, Ahlbrecht, Jonas, Puppe, Wolfram, Bönig, Lena, Sühs, Kurt-Wolfram, Stangel, Martin, Ganzenmueller, Tina, Skripuletz, Thomas

“…Blood contamination due to traumatic lumbar puncture presents a diagnostic pitfall in cerebrospinal fluid (CSF) analysis. It is controversially discussed if…”
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Investigation of Oligoclonal IgG Bands in Tear Fluid of Multiple Sclerosis Patients by Hümmert, Martin W, Wurster, Ulrich, Bönig, Lena, Schwenkenbecher, Philipp, Sühs, Kurt-Wolfram, Alvermann, Sascha, Gingele, Stefan, Skripuletz, Thomas, Stangel, Martin

“…Oligoclonal IgG bands (OCB) in the cerebrospinal fluid (CSF) represent a typical marker for inflammation in multiple sclerosis (MS) patients and have a…”
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Cerebrospinal fluid features in adults with enteroviral nervous system infection by Ahlbrecht, Jonas, Hillebrand, Lilly Katrin, Schwenkenbecher, Philipp, Ganzenmueller, Tina, Heim, Albert, Wurster, Ulrich, Stangel, Martin, Sühs, Kurt-Wolfram, Skripuletz, Thomas

“…•The cerebrospinal fluid (CSF) cell count was normal in 15% of all patients.•Patients with normal CSF cell counts were older and less frequently had…”
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Decreased Intrathecal Concentrations of Free Light Chains Kappa in Multiple Sclerosis Patients Taking Very High Effective Disease-Modifying Treatment by Süße, Marie, Konen, Franz Felix, Schwenkenbecher, Philipp, Budde, Kathrin, Nauck, Matthias, Grothe, Matthias, Hannich, Malte Johannes, Skripuletz, Thomas

“…Free light chains kappa (FLCκ) in cerebrospinal fluid (CSF) are a part of the intrathecal immune response. This observational study was conducted to…”
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Evidence of Oligoclonal Bands Does Not Exclude Non-Inflammatory Neurological Diseases by Pannewitz-Makaj, Katharina, Wurster, Ulrich, Jendretzky, Konstantin Fritz, Gingele, Stefan, Sühs, Kurt-Wolfram, Stangel, Martin, Skripuletz, Thomas, Schwenkenbecher, Philipp

“…Cerebrospinal fluid analysis is an essential part of the diagnostic workup in various neurological disorders. Evidence of an intrathecal immunoglobulin…”
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The Influence of Renal Function Impairment on Kappa Free Light Chains in Cerebrospinal Fluid by Konen, Franz F, Schwenkenbecher, Philipp, Wurster, Ulrich, Jendretzky, Konstantin F, Möhn, Nora, Gingele, Stefan, Sühs, Kurt-Wolfram, Hannich, Malte J, Grothe, Matthias, Witte, Torsten, Stangel, Martin, Süße, Marie, Skripuletz, Thomas

“…Background The determination of kappa free light chains (KFLC) in cerebrospinal fluid (CSF) is an upcoming biomarker for the detection of an intrathecal…”
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The Impact of Immunomodulatory Treatment on Kappa Free Light Chains as Biomarker in Neuroinflammation by Konen, Franz Felix, Wurster, Ulrich, Witte, Torsten, Jendretzky, Konstantin Fritz, Gingele, Stefan, Tumani, Hayrettin, Sühs, Kurt-Wolfram, Stangel, Martin, Schwenkenbecher, Philipp, Skripuletz, Thomas

“…Kappa free light chains (KFLC) are a promising new biomarker to detect neuroinflammation. Still, the impact of pre-analytical effects on KFLC concentrations…”
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Prevalence of comorbid autoimmune diseases and antibodies in newly diagnosed multiple sclerosis patients by Jendretzky, Konstantin Fritz, Lezius, Lisa-Marie, Thiele, Thea, Konen, Franz Felix, Huss, André, Heitmann, Lena, Güzeloglu, Yunus Emre, Schwenkenbecher, Philipp, Sühs, Kurt-Wolfram, Skuljec, Jelena, Wattjes, Mike Peter, Witte, Torsten, Kleinschnitz, Christoph, Pul, Refik, Tumani, Hayrettin, Gingele, Stefan, Skripuletz, Thomas

“…Abstract Background Diagnosing multiple sclerosis (MS) is challenging due to diverse symptoms and the absence of specific biomarkers. Concurrent autoimmune…”
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