Search Results - "SCHWARTZ, Ann V"

Mechanisms of diabetes mellitus-induced bone fragility by Napoli, Nicola, Chandran, Manju, Pierroz, Dominique D., Abrahamsen, Bo, Schwartz, Ann V., Ferrari, Serge L.

“…Key Points Patients with type 1 diabetes mellitus or type 2 diabetes mellitus (T2DM) have an increased risk of fractures; BMD underestimates this risk in…”
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Marrow fat and bone: review of clinical findings by Schwartz, Ann V

“…With growing interest in the connection between fat and bone, there has been increased investigation of the relationship with marrow fat in particular…”
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Efficacy of Osteoporosis Therapies in Diabetic Patients by Schwartz, Ann V.

“…Diabetes is characterized by increased fracture risk and by reduced bone strength for a given density. Contributing factors may include lower bone turnover and…”
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Skeletal Metabolism, Fracture Risk, and Fracture Outcomes in Type 1 and Type 2 Diabetes by Sellmeyer, Deborah E, Civitelli, Roberto, Hofbauer, Lorenz C, Khosla, Sundeep, Lecka-Czernik, Beata, Schwartz, Ann V

“…Fracture risk is significantly increased in both type 1 and type 2 diabetes, and individuals with diabetes experience worse fracture outcomes than…”
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Type 2 diabetes and bone by Leslie, William D, Rubin, Mishaela R, Schwartz, Ann V, Kanis, John A

“…There is a growing body of research showing that diabetes is an independent risk factor for fracture. Type 2 diabetes (T2D), which predominates in older…”
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Effect of Two‐Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non‐Obese Younger Adults: A Randomized Clinical Trial by Villareal, Dennis T, Fontana, Luigi, Das, Sai Krupa, Redman, Leanne, Smith, Steven R, Saltzman, Edward, Bales, Connie, Rochon, James, Pieper, Carl, Huang, Megan, Lewis, Michael, Schwartz, Ann V

“…ABSTRACT Although caloric restriction (CR) could delay biologic aging in humans, it is unclear if this would occur at the cost of significant bone loss. We…”
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Body Composition Remodeling and Mortality: The Health Aging and Body Composition Study by Santanasto, Adam J, Goodpaster, Bret H, Kritchevsky, Stephen B, Miljkovic, Iva, Satterfield, Suzanne, Schwartz, Ann V, Cummings, Steven R, Boudreau, Robert M, Harris, Tamara B, Newman, Anne B

“…Age-related losses of lean mass and shifts to central adiposity are related to functional decline and may predict mortality and/or explain part of the risk of…”
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Continuing Bisphosphonate Treatment for Osteoporosis — For Whom and for How Long? by Black, Dennis M, Bauer, Douglas C, Schwartz, Ann V, Cummings, Steven R, Rosen, Clifford J

“…There is controversy over the ideal duration of bisphosphonate therapy for osteoporosis, given reports of atypical subtrochanteric fractures and osteonecrosis…”
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Bone and glucose metabolism: A two-way street by Motyl, Katherine J., McCabe, Laura R., Schwartz, Ann V.

“…Evidence from rodent models indicates that undercarboxylated osteocalcin (ucOC), a product of osteoblasts, is a hormone affecting insulin production by the…”
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Diabetes-Related Complications, Glycemic Control, and Falls in Older Adults by Schwartz, Ann V, Vittinghoff, Eric, Sellmeyer, Deborah E, Feingold, Kenneth R, Rekeneire, Nathalie de, Strotmeyer, Elsa S, Shorr, Ronald I, Vinik, Aaron I, Odden, Michelle C, Park, Seok Won, Faulkner, Kimberly A, Harris, Tamara B

“…OBJECTIVE:--Older adults with type 2 diabetes are more likely to fall, but little is known about risk factors for falls in this population. We determined…”
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Diabetes and Risk of Hospitalized Fall Injury Among Older Adults by YAU, Rebecca K, STROTMEYER, Elsa S, CUMMINGS, Steven R, SHORR, Ronald I, SCHWARTZ, Ann V, RESNICK, Helaine E, SELLMEYER, Deborah E, FEINGOLD, Kenneth R, CAULEY, Jane A, VITTINGHOFF, Eric, DE REKENEIRE, Nathalie, HARRIS, Tamara B, NEVITT, Michael C

“…To determine whether older adults with diabetes are at increased risk of an injurious fall requiring hospitalization. The longitudinal Health, Aging, and Body…”
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Effects of TZD Use and Discontinuation on Fracture Rates in ACCORD Bone Study by Schwartz, Ann V, Chen, Haiying, Ambrosius, Walter T, Sood, Ajay, Josse, Robert G, Bonds, Denise E, Schnall, Adrian M, Vittinghoff, Eric, Bauer, Douglas C, Banerji, Mary Ann, Cohen, Robert M, Hamilton, Bruce P, Isakova, Tamara, Sellmeyer, Deborah E, Simmons, Debra L, Shibli-Rahhal, Amal, Williamson, Jeff D, Margolis, Karen L

“…Context: In trials, thiazolidinediones (TZDs) increase fracture risk in women, but the effects of discontinuation are unknown. Objective: The objective was to…”
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Effects of antiresorptive therapies on glucose metabolism: Results from the FIT, HORIZON‐PFT, and FREEDOM trials by Schwartz, Ann V, Schafer, Anne L, Grey, Andrew, Vittinghoff, Eric, Palermo, Lisa, Lui, Li‐Yung L, Wallace, Robert B, Cummings, Steven R, Black, Dennis M, Bauer, Douglas C, Reid, Ian R

“…ABSTRACT In rodent models, undercarboxylated osteocalcin (ucOC) acts as a hormone that promotes insulin sensitivity and secretion. If ucOC plays a similar role…”
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Low Plasma Klotho Concentrations and Decline of Knee Strength in Older Adults by Semba, Richard D, Ferrucci, Luigi, Sun, Kai, Simonsick, Eleanor, Turner, Randi, Miljkovic, Iva, Harris, Tamara, Schwartz, Ann V, Asao, Keiko, Kritchevsky, Stephen, Newman, Anne B

“…Although the "anti-aging hormone" klotho is associated with sarcopenia in mice, the relationship between klotho and muscle strength in older adults is not well…”
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Insulin Resistance Is Associated With Decreased Quadriceps Muscle Strength in Nondiabetic Adults Aged ≥70 Years by BARZILAY, Joshua I, SATTERFIELD, Suzanne, COTSONIS, George A, MILJKOVIC, Iva, WALSTON, Jeremy, HARRIS, Tamara B, SCHWARTZ, Ann V

“…Insulin Resistance Is Associated With Decreased Quadriceps Muscle Strength in Nondiabetic Adults Aged ≥70 Years Joshua I. Barzilay , MD 1 , George A. Cotsonis…”
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Diabetes, bone and glucose-lowering agents: clinical outcomes by Schwartz, Ann V.

“…Older adults with diabetes are at higher risk of fracture and of complications resulting from a fracture. Hence, fracture risk reduction is an important goal…”
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Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the ACTIVE Study by Dhaliwal, Ruban, Hans, Didier, Hattersley, Gary, Mitlak, Bruce, Fitzpatrick, Lorraine A, Wang, Yamei, Schwartz, Ann V, Miller, Paul D, Josse, Robert G

“…ABSTRACT Type 2 diabetes mellitus (T2DM) increases fracture risk despite normal or increased BMD. Abaloparatide reduces fracture risk in patients with…”
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Sensory and Motor Peripheral Nerve Function and Incident Mobility Disability by Ward, Rachel E., Boudreau, Robert M., Caserotti, Paolo, Harris, Tamara B., Zivkovic, Sasa, Goodpaster, Bret H., Satterfield, Suzanne, Kritchevsky, Stephen B., Schwartz, Ann V., Vinik, Aaron I., Cauley, Jane A., Simonsick, Eleanor M., Newman, Anne B., Strotmeyer, Elsa S.

“…Objectives To assess the relationship between sensorimotor nerve function and incident mobility disability over 10 years. Design Prospective cohort study with…”
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Epidemiology of fractures in type 2 diabetes by Schwartz, Ann V

“…Abstract Type 2 diabetes affects an increasing proportion of older adults, the population that is also at elevated risk of fracture. Type 2 diabetes itself…”
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Microvascular disease not type 2 diabetes is associated with increased cortical porosity: A study of cortical bone microstructure and intracortical vessel characteristics by Löffler, Maximilian T., Wu, Po-hung, Pirmoazen, Amir M., Joseph, Gabby B., Stewart, Jay M., Saeed, Isra, Liu, Jing, Schafer, Anne L., Schwartz, Ann V., Link, Thomas M., Kazakia, Galateia J.

“…Fracture risk is elevated in type 2 diabetes (T2D) despite normal or even high bone mineral density (BMD). Microvascular disease (MVD) is a diabetic…”
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