Search Results - "SCHUMICH, Angela"

Erratum to : Genomic breakpoint-specific monitoring of measurable residual disease in pediatric non-standard risk acute myeloid leukemia by Maurer-Granofszky, Margarita, Köhrer, Stefan, Fischer, Susanna, Schumich, Angela, Nebral, Karin, Larghero, Patrizia, Meyer, Claus, Mecklenbräuker, Astrid, Mühlegger, Nora, Marschalek, Rolf, Haas, Oskar A, Panzer-Grümayer, Renate, Dworzak, Michael N

Get full text

Genomic breakpoint-specific monitoring of measurable residual disease in pediatric non-standard-risk acute myeloid leukemia by Maurer-Granofszky, Margarita, Kohrer, Stefan, Fischer, Susanna, Schumich, Angela, Nebral, Karin, Larghero, Patrizia, Meyer, Claus, Mecklenbrauker, Astrid, Muhlegger, Nora, Marschalek, Rolf, Haas, Oskar A, Panzer-Grumayer, Renate, Dworzak, Michael N

“…Pediatric acute myeloid leukemia (AML) is a highly heterogeneous disease making standardized measurable residual disease (MRD) assessment challenging…”
Get full text

CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immunotherapy by Dworzak, Michael N., Schumich, Angela, Printz, Dieter, Pötschger, Ulrike, Husak, Zvenyslava, Attarbaschi, Andishe, Basso, Giuseppe, Gaipa, Giuseppe, Ratei, Richard, Mann, Georg, Gadner, Helmut

“…CD20 is expressed in approximately one- half of pediatric acute lymphoblastic leukemia (ALL) cases with B-cell precursor (BCP) origin. We observed that it is…”
Get full text

Risk factors in DUX4-positive childhood and adolescent B-cell acute lymphoblastic leukemia by Schinnerl, Dagmar, Riebler, Marion, Schumich, Angela, Haslinger, Sabrina, Bramböck, Alice, Inthal, Andrea, Nykiel, Marek, Maurer-Granofszky, Margarita, Haas, Oskar A., Pötschger, Ulrike, Köhrer, Stefan, Nebral, Karin, Dworzak, Michael N., Attarbaschi, Andishe, Strehl, Sabine

Get full text

Death induction by CD99 ligation in TEL/AML1-positive acute lymphoblastic leukemia and normal B cell precursors by Husak, Zvenyslava, Printz, Dieter, Schumich, Angela, Pötschger, Ulrike, Dworzak, Michael N.

“…Results suggest that CD99 may play a physiologic role in the clonal deletion processes necessary for B‐lymphoid selection. Our study was performed to examine…”
Get full text

CD371 cell surface expression: a unique feature of DUX4 -rearranged acute lymphoblastic leukemia by Schinnerl, Dagmar, Mejstrikova, Ester, Schumich, Angela, Zaliova, Marketa, Fortschegger, Klaus, Nebral, Karin, Attarbaschi, Andishe, Fiser, Karel, Kauer, Maximilian O, Popitsch, Niko, Haslinger, Sabrina, Inthal, Andrea, Buldini, Barbara, Basso, Giuseppe, Bourquin, Jean-Pierre, Gaipa, Giuseppe, Brüggemann, Monika, Feuerstein, Tamar, Maurer-Granofszky, Margarita, Panzer-Grümayer, Renate, Trka, Jan, Mann, Georg, Haas, Oskar A, Hrusak, Ondrej, Dworzak, Michael N, Strehl, Sabine

Get full text

Phospho‐Profiling Linking Biology and Clinics in Pediatric Acute Myeloid Leukemia by Schumich, Angela, Prchal‐Murphy, Michaela, Maurer‐Granofszky, Margarita, Hoelbl‐Kovacic, Andrea, Mühlegger, Nora, Pötschger, Ulrike, Fajmann, Sabine, Haas, Oskar A., Nebral, Karin, Neuhoff, Nils von, Zimmermann, Martin, Boztug, Heidrun, Rasche, Mareike, Dolezal, Marlies, Walter, Christiane, Reinhardt, Dirk, Sexl, Veronika, Dworzak, Michael N.

“…Supplemental Digital Content is available in the text Aberrant activation of key signaling‐molecules is a hallmark of acute myeloid leukemia (AML) and may have…”
Get full text

AIEOP‐BFM Consensus Guidelines 2016 for Flow Cytometric Immunophenotyping of Pediatric Acute Lymphoblastic Leukemia by Dworzak, Michael N., Buldini, Barbara, Gaipa, Giuseppe, Ratei, Richard, Hrusak, Ondrej, Luria, Drorit, Rosenthal, Eti, Bourquin, Jean‐Pierre, Sartor, Mary, Schumich, Angela, Karawajew, Leonid, Mejstrikova, Ester, Maglia, Oscar, Mann, Georg, Ludwig, Wolf‐Dieter, Biondi, Andrea, Schrappe, Martin, Basso, Giuseppe

“…Immunophenotyping by flow cytometry (FCM) is a worldwide mainstay in leukemia diagnostics. For concordant multicentric application, however, a gap exists…”
Get full text

CD371-positive pediatric B-cell acute lymphoblastic leukemia: propensity to lineage switch and slow early response to treatment by Buldini, Barbara, Varotto, Elena, Maurer-Granofszky, Margarita, Gaipa, Giuseppe, Schumich, Angela, Brüggemann, Monika, Mejstrikova, Ester, Cazzaniga, Giovanni, Hrusak, Ondrej, Szczepanowski, Monika, Scarparo, Pamela, Zimmermann, Martin, Strehl, Sabine, Schinnerl, Dagmar, Zaliova, Marketa, Karawajew, Leonid, Bourquin, Jean-Pierre, Feuerstein, Tamar, Cario, Gunnar, Alten, Julia, Möricke, Anja, Biffi, Alessandra, Parasole, Rosanna, Fagioli, Franca, Valsecchi, Maria Grazia, Biondi, Andrea, Locatelli, Franco, Attarbaschi, Andishe, Schrappe, Martin, Conter, Valentino, Basso, Giuseppe, Dworzak, Michael N.

“…•Pediatric CD371-positive B-cell precursor acute lymphoblastic leukemia shows transient lineage switch and slow early response to treatment.•Accurate…”
Get full text

Automated Flow Cytometric MRD Assessment in Childhood Acute B‐ Lymphoblastic Leukemia Using Supervised Machine Learning by Reiter, Michael, Diem, Markus, Schumich, Angela, Maurer‐Granofszky, Margarita, Karawajew, Leonid, Rossi, Jorge G., Ratei, Richard, Groeneveld‐Krentz, Stefanie, Sajaroff, Elisa O., Suhendra, Susanne, Kampel, Martin, Dworzak, Michael N.

“…Minimal residual disease (MRD) as measured by multiparameter flow cytometry (FCM) is an independent and strong prognostic factor in B‐cell acute lymphoblastic…”
Get full text

UMAP Based Anomaly Detection for Minimal Residual Disease Quantification within Acute Myeloid Leukemia by Weijler, Lisa, Kowarsch, Florian, Wödlinger, Matthias, Reiter, Michael, Maurer-Granofszky, Margarita, Schumich, Angela, Dworzak, Michael N

“…Leukemia is the most frequent malignancy in children and adolescents, with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) as the most…”
Get full text

Automated identification of cell populations in flow cytometry data with transformers by Wödlinger, Matthias, Reiter, Michael, Weijler, Lisa, Maurer-Granofszky, Margarita, Schumich, Angela, Sajaroff, Elisa O., Groeneveld-Krentz, Stefanie, Rossi, Jorge G., Karawajew, Leonid, Ratei, Richard, Dworzak, Michael N.

“…Acute Lymphoblastic Leukemia (ALL) is the most frequent hematologic malignancy in children and adolescents. A strong prognostic factor in ALL is given by the…”
Get full text

FCM marker importance for MRD assessment in T‐cell acute lymphoblastic leukemia: An AIEOP‐BFM‐ALL‐FLOW study group report by Kowarsch, Florian, Maurer‐Granofszky, Margarita, Weijler, Lisa, Wödlinger, Matthias, Reiter, Michael, Schumich, Angela, Feuerstein, Tamar, Sala, Simona, Nováková, Michaela, Faggin, Giovanni, Gaipa, Giuseppe, Hrusak, Ondrej, Buldini, Barbara, Dworzak, Michael N.

“…T‐lineage acute lymphoblastic leukemia (T‐ALL) accounts for about 15% of pediatric and about 25% of adult ALL cases. Minimal/measurable residual disease (MRD)…”
Get full text

Flow‐cytometric minimal residual disease monitoring in blood predicts relapse risk in pediatric B‐cell precursor acute lymphoblastic leukemia in trial AIEOP‐BFM‐ALL 2000 by Schumich, Angela, Maurer‐Granofszky, Margarita, Attarbaschi, Andishe, Pötschger, Ulrike, Buldini, Barbara, Gaipa, Giuseppe, Karawajew, Leonid, Printz, Dieter, Ratei, Richard, Conter, Valentino, Schrappe, Martin, Mann, Georg, Basso, Giuseppe, Dworzak, Michael N.

“…Background Flow‐cytometric monitoring of minimal residual disease (MRD) in bone marrow (BM) during induction of pediatric patients with acute lymphoblastic…”
Get full text

Transient Switch to Myeloid Lineage in Acute Lymphoblastic Leukemia during Induction Therapy: The Role of CD371 Expression and Implication for Minimal Residual Disease Detection by Varotto, Elena, Maurer-Granofszky, Margarita, Silvestri, Daniela, Scarparo, Pamela, Mejstrikova, Ester, Brüggemann, Monika, Cazzaniga, Giovanni, Conter, Valentino, Hrusak, Ondrej, Gaipa, Giuseppe, Schumich, Angela, Valsecchi, Maria Grazia, Basso, Giuseppe, Dworzak, Michael, Buldini, Barbara

“…Background Multiparametric flow cytometry (MFC) is critical in the diagnosis and management of pediatric acute lymphoblastic leukemia (ALL), through…”
Get full text

Detecting Rare Cell Populations in Flow Cytometry Data Using UMAP by Weijler, Lisa, Diem, Markus, Reiter, Michael, Maurer-Granofszky, Margarita

“…We present an approach to detecting small cell populations in flow cytometry (FCM) samples based on the combination of unsupervised manifold embedding and…”
Get full text

Concurrent Acute Myelofibrosis and Acute Lymphoblastic Leukemia in Childhood: Case Report and Review of the Literature by Friesenbichler, Waltraud, Schumich, Angela, Simonitsch-Klupp, Ingrid, Panzer-Grümayer, Renate, Haas, Oskar, Mann, Georg, Dworzak, Michael

“…Myelofibrosis is associated with a wide variety of neoplastic and non-neoplastic bone marrow diseases, predominately myeloproliferative neoplasms and acute…”
Get full text

Time point-dependent concordance of flow cytometry and real-time quantitative polymerase chain reaction for minimal residual disease detection in childhood acute lymphoblastic leukemia by GAIPA, Giuseppe, CAZZANIGA, Giovanni, SALA, Simona, SCHUMICH, Angela, SCHRAUDER, Andre, VILLA, Tiziana, VELTRONI, Marinella, LUDWIG, Wolf-Dieter, CONTER, Valentino, SCHRAPPE, Martin, BIONDI, Andrea, DWORZAK, Michael N, GRAZIA VALSECCHI, Maria, BASSO, Giuseppe, PANZER-GRÜMAYER, Renate, BULDINI, Barbara, SILVESTRI, Daniela, KARAWAJEW, Leonid, MAGLIA, Oscar, RATEI, Richard, BENETELLO, Alessandra

“…Flow cytometric analysis of leukemia-associated immunophenotypes and polymerase chain reaction-based amplification of antigen-receptor genes rearrangements are…”
Get full text

WGAN Latent Space Embeddings for Blast Identification in Childhood Acute Myeloid Leukaemia by Licandro, Roxane, Schlegl, Thomas, Reiter, Michael, Diem, Markus, Dworzak, Michael, Schumich, Angela, Langs, Georg, Kampel, Martin

“…Acute Myeloid Leukaemia (AML) is a rare type of childhood acute leukaemia. During treatment, the assessment of the number of cancer cells is particularly…”
Get full text

Modulation of antigen expression in B‐cell precursor acute lymphoblastic leukemia during induction therapy is partly transient: Evidence for a drug‐induced regulatory phenomenon. Results of the AIEOP‐BFM‐ALL‐FLOW‐MRD‐Study Group by Dworzak, Michael N., Gaipa, Giuseppe, Schumich, Angela, Maglia, Oscar, Ratei, Richard, Veltroni, Marinella, Husak, Zvenyslava, Basso, Giuseppe, Karawajew, Leonid, Gadner, Helmut, Biondi, Andrea

“…Background: Changes of antigen expression on residual blast cells of acute lymphoblastic leukemia (ALL) occur during induction treatment. Many markers used for…”
Get full text