Search Results - "SCHUMACHER, Sarah"

Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis by Garikipati, Venkata Naga Srikanth, Verma, Suresh Kumar, Cheng, Zhongjian, Liang, Dongming, Truongcao, May M., Cimini, Maria, Yue, Yujia, Huang, Grace, Wang, Chunlin, Benedict, Cindy, Tang, Yan, Mallaredy, Vandana, Ibetti, Jessica, Grisanti, Laurel, Schumacher, Sarah M., Gao, Erhe, Rajan, Sudarsan, Wilusz, Jeremy E., Goukassian, David, Houser, Steven R., Koch, Walter J., Kishore, Raj

“…Circular RNAs are generated from many protein-coding genes, but their role in cardiovascular health and disease states remains unknown. Here we report…”
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Tumor Necrosis Factor-α in Heart Failure: an Updated Review by Schumacher, Sarah M., Naga Prasad, Sathyamangla V.

“…Purpose of the Review Proinflammatory cytokines are consistently elevated in congestive heart failure. In the current review, we provide an overview on the…”
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Menstrual cycle-related fluctuations in oxytocin concentrations: A systematic review and meta-analysis by Engel, Sinha, Klusmann, Hannah, Ditzen, Beate, Knaevelsrud, Christine, Schumacher, Sarah

“…•Oxytocin significantly increased from the early follicular phase to ovulation.•Oxytocin significantly decreased from ovulation to the mid-luteal phase.•There…”
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Short-term use of an Impella ventricular assist device sterile water-based bicarbonate purge solution for positron emission tomography scanning by Schumacher, Sarah M, Hobbs, Ryan A

“…In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been…”
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Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK by Nagai, Jun, Bellafard, Arash, Qu, Zhe, Yu, Xinzhu, Ollivier, Matthias, Gangwani, Mohitkumar R., Diaz-Castro, Blanca, Coppola, Giovanni, Schumacher, Sarah M., Golshani, Peyman, Gradinaru, Viviana, Khakh, Baljit S.

“…Astrocytes respond to neurotransmitters and neuromodulators using G-protein-coupled receptors (GPCRs) to mediate physiological responses. Despite their…”
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The Challenge of Mentorship by Schumacher, Sarah M

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HPA axis regulation in posttraumatic stress disorder: A meta-analysis focusing on potential moderators by Schumacher, Sarah, Niemeyer, Helen, Engel, Sinha, Cwik, Jan Christopher, Laufer, Sebastian, Klusmann, Hannah, Knaevelsrud, Christine

“…•Overall, morning and 24 h cortisol was significantly lower in PTSD than controls (trauma-exposed and non-trauma exposed controls).•No clear pattern of…”
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Long-term outcomes of psychological treatment for posttraumatic stress disorder: a systematic review and meta-analysis by Weber, Maxi, Schumacher, Sarah, Hannig, Wiebke, Barth, Jürgen, Lotzin, Annett, Schäfer, Ingo, Ehring, Thomas, Kleim, Birgit

“…Several types of psychological treatment for posttraumatic stress disorder (PTSD) are considered well established and effective, but evidence of their…”
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Paroxetine-mediated GRK2 inhibition reverses cardiac dysfunction and remodeling after myocardial infarction by Schumacher, Sarah M, Gao, Erhe, Zhu, Weizhong, Chen, Xiongwen, Chuprun, J Kurt, Feldman, Arthur M, Tesmer, John J G, Koch, Walter J

“…Heart failure (HF) is a disease of epidemic proportion and is associated with exceedingly high health care costs. G protein (heterotrimeric guanine…”
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G protein-coupled receptor kinase 2 promotes cardiac hypertrophy by Schlegel, Philipp, Reinkober, Julia, Meinhardt, Eric, Tscheschner, Henrike, Gao, Erhe, Schumacher, Sarah M, Yuan, Ancai, Backs, Johannes, Most, Patrick, Wieland, Thomas, Koch, Walter J, Katus, Hugo A, Raake, Philip W

“…The increase in protein activity and upregulation of G-protein coupled receptor kinase 2 (GRK2) is a hallmark of cardiac stress and heart failure. Inhibition…”
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A cardiac amino-terminal GRK2 peptide inhibits insulin resistance yet enhances maladaptive cardiovascular and brown adipose tissue remodeling in females during diet-induced obesity by Manaserh, Iyad H., Bledzka, Kamila M., Ampong, Isaac, Junker, Alex, Grondolsky, Jessica, Schumacher, Sarah M.

“…Obesity and metabolic disorders are increasing in epidemic proportions, leading to poor outcomes including heart failure. With a growing recognition of the…”
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Demographic, sampling- and assay-related confounders of endogenous oxytocin concentrations: A systematic review and meta-analysis by Engel, Sinha, Laufer, Sebastian, Miller, Robert, Niemeyer, Helen, Knaevelsrud, Christine, Schumacher, Sarah

“…•Oxytocin concentrations depend on specimen and extraction.•Oxytocin concentrations are higher in women than in men.•Oxytocin concentrations increase with…”
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Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia by Milstein, Michelle L., Musa, Hassan, Balbuena, Daniela Ponce, Anumonwo, Justus M. B., Auerbach, David S., Furspan, Philip B., Hou, Luqia, Hu, Bin, Schumacher, Sarah M., Vaidyanathan, Ravi, Martens, Jeffrey R., Jalife, José

“…The cardiac electrical impulse depends on an orchestrated interplay of transmembrane ionic currents in myocardial cells. Two critical ionic current mechanisms…”
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Noncanonical Roles of G Protein-coupled Receptor Kinases in Cardiovascular Signaling by Schumacher, Sarah M, Koch, Walter J

“…G protein-coupled receptor kinases (GRKs) are classically known for their role in regulating the activity of the largest known class of membrane receptors,…”
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Systematic Review of Invasive Meningococcal Disease: Sequelae and Quality of Life Impact on Patients and Their Caregivers by Olbrich, Kerstin J., Müller, Dirk, Schumacher, Sarah, Beck, Ekkehard, Meszaros, Kinga, Koerber, Florian

“…Introduction Invasive meningococcal disease (IMD, septicaemia and/or meningitis) has a severe acute and long-term burden: 5–10% of patients die within 48 h,…”
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Interleukin-10 Inhibits Bone Marrow Fibroblast Progenitor Cell–Mediated Cardiac Fibrosis in Pressure-Overloaded Myocardium by Verma, Suresh K, Garikipati, Venkata N.S, Krishnamurthy, Prasanna, Schumacher, Sarah M, Grisanti, Laurel A, Cimini, Maria, Cheng, Zhongjian, Khan, Mohsin, Yue, Yujia, Benedict, Cindy, Truongcao, May M, Rabinowitz, Joseph E, Goukassian, David A, Tilley, Douglas, Koch, Walter J, Kishore, Raj

“…BACKGROUND:Activated fibroblasts (myofibroblasts) play a critical role in cardiac fibrosis; however, their origin in the diseased heart remains unclear,…”
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Characterization of βARKct engineered cellular extracellular vesicles and model specific cardioprotection by Kwon, Jin-Sook, Schumacher, Sarah M, Gao, Erhe, Chuprun, J Kurt, Ibetti, Jessica, Roy, Rajika, Khan, Mohsin, Kishore, Raj, Koch, Walter J

“…Recent data supporting any benefit of stem cell therapy for ischemic heart disease have suggested paracrine-based mechanisms via extracellular vesicles (EVs)…”
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A peptide of the amino-terminus of GRK2 induces hypertrophy and yet elicits cardioprotection after pressure overload by Bledzka, Kamila M., Manaserh, Iyad H., Grondolsky, Jessica, Pfleger, Jessica, Roy, Rajika, Gao, Erhe, Chuprun, J. Kurt, Koch, Walter J., Schumacher, Sarah M.

“…G protein-coupled receptor (GPCR) kinase 2 (GRK2) expression and activity are elevated early on in response to several forms of cardiovascular stress and are a…”
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Diagnostic leukapheresis enables reliable detection of circulating tumor cells of nonmetastatic cancer patients by Fischer, Johannes C., Niederacher, Dieter, Topp, Stefan A., Honisch, Ellen, Schumacher, Sarah, Schmitz, Norma, Föhrding, Luisa Zacarias, Vay, Christian, Hoffmann, Imke, Kasprowicz, Nikola S., Hepp, Philip G., Mohrmann, Svjetlana, Nitz, Ulrike, Stresemann, Antje, Krahn, Thomas, Henze, Tanja, Griebsch, Evelyn, Raba, Katharina, Rox, Jutta M., Wenzel, Folker, Sproll, Christoph, Janni, Wolfgang, Fehm, Tanja, Klein, Christoph A., Knoefel, Wolfram Trudo, Stoecklein, Nikolas H.

“…Circulating tumor cells (CTCs) are promising biomarkers for diagnosis and therapy in systemic cancer. However, their infrequent and unreliable detection,…”
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Cross-modal object recognition and dynamic weighting of sensory inputs in a fish by Schumacher, Sarah, de Perera, Theresa Burt, Thenert, Johanna, von der Emde, Gerhard

“…Most animals use multiple sensory modalities to obtain information about objects in their environment. There is a clear adaptive advantage to being able to…”
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