Search Results - "SCHUMACHER, M"
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A novel strontium(II)-modified calcium phosphate bone cement stimulates human-bone-marrow-derived mesenchymal stem cell proliferation and osteogenic differentiation in vitro
Published in Acta biomaterialia (01-12-2013)“…Stimulation of hMSC differentiation by Sr2+-modifid CaP bone cements. In the present study, the in vitro effects of novel strontium-modified calcium phosphate…”
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Mesoporous bioactive glass composition effects on degradation and bioactivity
Published in Bioactive materials (01-07-2021)“…Mesoporous bioactive glasses (MBGs) are promising materials for regenerative medicine, due to their favorable properties including bioactivity and…”
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Revisiting the roles of progesterone and allopregnanolone in the nervous system: resurgence of the progesterone receptors
Published in Progress in neurobiology (01-02-2014)“…Progesterone is commonly considered as a female reproductive hormone and is well-known for its role in pregnancy. It is less well appreciated that progesterone…”
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Identification of CMTM6 and CMTM4 as PD-L1 protein regulators
Published in Nature (London) (07-09-2017)“…CMTM6 and CMTM4 bind to and stabilize the inhibitory receptor PD-L1 and regulate PD-L1 levels at the surface of human tumour and immune cells. Regulating…”
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Successful Function of Autologous iPSC-Derived Dopamine Neurons following Transplantation in a Non-Human Primate Model of Parkinson’s Disease
Published in Cell stem cell (05-03-2015)“…Autologous transplantation of patient-specific induced pluripotent stem cell (iPSC)-derived neurons is a potential clinical approach for treatment of…”
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Diagnostic stability of 346 patients with borderline personality disorder based on retrospective clinical records
Published in European psychiatry (01-03-2023)“…Introduction State-of-the-art research highlights that borderline personality disorder have high rates of comorbid Axis I disorders, which imply uncertainty in…”
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Strontium-modified premixed calcium phosphate cements for the therapy of osteoporotic bone defects
Published in Acta biomaterialia (01-01-2018)“…[Display omitted] In this study a premixed strontium-containing calcium phosphate bone cement for the application in osteoporotic bone defects has been…”
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Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis
Published in Nature communications (20-09-2019)“…Circular RNAs are generated from many protein-coding genes, but their role in cardiovascular health and disease states remains unknown. Here we report…”
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Antimüllerian hormone as a risk factor for miscarriage in naturally conceived pregnancies
Published in Fertility and sterility (01-06-2018)“…To determine the association between antimüllerian hormone (AMH), a measure of ovarian reserve, and miscarriage among naturally conceived pregnancies…”
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10
Understanding the global hydrological droughts of 2003–2016 and their relationships with teleconnections
Published in The Science of the total environment (10-02-2019)“…Droughts often evolve gradually and cover large areas, and therefore, affect many people and activities. This motivates developing techniques to integrate…”
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Chemical activation of the mechanotransduction channel Piezo1
Published in eLife (22-05-2015)“…Piezo ion channels are activated by various types of mechanical stimuli and function as biological pressure sensors in both vertebrates and invertebrates. To…”
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Comparing multi-objective optimization techniques to calibrate a conceptual hydrological model using in situ runoff and daily GRACE data
Published in Computational geosciences (01-06-2018)“…Hydrological models are necessary tools for simulating the water cycle and for understanding changes in water resources. To achieve realistic model simulation…”
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A sequential calibration approach based on the ensemble Kalman filter (C-EnKF) for forecasting total electron content (TEC)
Published in Journal of geodesy (01-04-2022)“…Ionospheric models are applied for computing the Total Electron Content (TEC) in ionosphere to reduce its effects on the Global Navigation Satellite System…”
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Improving drought simulations within the Murray-Darling Basin by combined calibration/assimilation of GRACE data into the WaterGAP Global Hydrology Model
Published in Remote sensing of environment (01-01-2018)“…Simulating hydrological processes within the (semi-)arid region of the Murray-Darling Basin (MDB), Australia, is very challenging specially during droughts. In…”
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Distribution of membrane progesterone receptor alpha in the male mouse and rat brain and its regulation after traumatic brain injury
Published in Neuroscience (12-02-2013)“…Highlights ► mPRα shows a wide distribution in the male rodent brain. ► In basal condition, mPRα is expressed by neurons but not in the glia. ► After TBI, mPRα…”
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Relevance of osteoclast-specific enzyme activities in cell-based in vitro resorption assays
Published in European cells & materials (18-01-2017)“…Cell-based in vitro resorption assays are an important tool to simulate the in vivo biodegradation of resorbable bone graft materials and to predict their…”
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Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain
Published in Nature communications (25-07-2022)“…3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is the rate-limiting enzyme in cholesterol synthesis and target of cholesterol-lowering statin drugs…”
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Interpreting and comparing risks in the presence of competing events
Published in BMJ (Online) (21-08-2014)“…Competing events are common in medical research. Ignoring them in the statistical analysis can easily lead to flawed results and conclusions. This article uses…”
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Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation
Published in PloS one (22-06-2015)“…Englerin A is a structurally unique natural product reported to selectively inhibit growth of renal cell carcinoma cell lines. A large scale phenotypic cell…”
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Exploring hydro-meteorological drought patterns over the Greater Horn of Africa (1979–2014) using remote sensing and reanalysis products
Published in Advances in water resources (01-08-2016)“…•Identification of 4 statistically independent regions facing hydro-meteorological droughts.•Hydrological and meteorological droughts are highly correlated…”
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