Search Results - "SCHUMACHER, DAVID"

Spatial multi-omic map of human myocardial infarction by Kuppe, Christoph, Ramirez Flores, Ricardo O., Li, Zhijian, Hayat, Sikander, Levinson, Rebecca T., Liao, Xian, Hannani, Monica T., Tanevski, Jovan, Wünnemann, Florian, Nagai, James S., Halder, Maurice, Schumacher, David, Menzel, Sylvia, Schäfer, Gideon, Hoeft, Konrad, Cheng, Mingbo, Ziegler, Susanne, Zhang, Xiaoting, Peisker, Fabian, Kaesler, Nadine, Saritas, Turgay, Xu, Yaoxian, Kassner, Astrid, Gummert, Jan, Morshuis, Michiel, Amrute, Junedh, Veltrop, Rogier J. A., Boor, Peter, Klingel, Karin, Van Laake, Linda W., Vink, Aryan, Hoogenboezem, Remco M., Bindels, Eric M. J., Schurgers, Leon, Sattler, Susanne, Schapiro, Denis, Schneider, Rebekka K., Lavine, Kory, Milting, Hendrik, Costa, Ivan G., Saez-Rodriguez, Julio, Kramann, Rafael

“…Myocardial infarction is a leading cause of death worldwide 1 . Although advances have been made in acute treatment, an incomplete understanding of remodelling…”
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Sleeve gastrectomy: 5-year outcomes of a single institution by Rawlins, Logan, M.D, Rawlins, Melissa P., M.P.A., P.A.-C, Brown, Carey C., M.D., F.A.C.S, Schumacher, David L., M.D., F.A.C.S

“…Abstract Background Laparoscopic sleeve gastrectomy (SG) is the most recent bariatric surgical procedure to gain universal acceptance by providers and payers…”
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Investigation on the uptake of ciprofloxacin, chloramphenicol and praziquantel by button mushrooms by Schildt, Julia, Rüdiger, Max, Richter, Annemarie, Schumacher, David M., Kürbis, Corinna

“…•Pharmacologically active substances may be present in button mushroom substrate.•Validation of LC-MS/MS method for 21 PAS in mushrooms.•Chloramphenicol…”
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Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner by Hoeft, Konrad, Schaefer, Gideon J.L., Kim, Hyojin, Schumacher, David, Bleckwehl, Tore, Long, Qingqing, Klinkhammer, Barbara Mara, Peisker, Fabian, Koch, Lars, Nagai, James, Halder, Maurice, Ziegler, Susanne, Liehn, Elisa, Kuppe, Christoph, Kranz, Jennifer, Menzel, Sylvia, Costa, Ivan, Wahida, Adam, Boor, Peter, Schneider, Rebekka K., Hayat, Sikander, Kramann, Rafael

“…Fibrosis represents the common end stage of chronic organ injury independent of the initial insult, destroying tissue architecture and driving organ failure…”
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Genotoxicity assessment: opportunities, challenges and perspectives for quantitative evaluations of dose–response data by Menz, Jakob, Götz, Mario E., Gündel, Ulrike, Gürtler, Rainer, Herrmann, Kristin, Hessel-Pras, Stefanie, Kneuer, Carsten, Kolrep, Franziska, Nitzsche, Dana, Pabel, Ulrike, Sachse, Benjamin, Schmeisser, Sebastian, Schumacher, David M., Schwerdtle, Tanja, Tralau, Tewes, Zellmer, Sebastian, Schäfer, Bernd

“…Genotoxicity data are mainly interpreted in a qualitative way, which typically results in a binary classification of chemical entities. For more than a decade,…”
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Electromagnetic Field (EMF) Profile and Baselines at a Non- Haunted Control Location by Schumacher, David, Biddle, Kenny, Vickers, Tim

“…There has been little to no environmental and experience data collected at randomlyselected non-haunted control sites despite the call for researchers and…”
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Neutrophils Modulate Fibroblast Function and Promote Healing and Scar Formation after Murine Myocardial Infarction by Curaj, Adelina, Schumacher, David, Rusu, Mihaela, Staudt, Mareike, Li, Xiaofeng, Simsekyilmaz, Sakine, Jankowski, Vera, Jankowski, Joachim, Dumitraşcu, Andreea Ramona, Hausenloy, Derek J, Schuh, Alexander, Liehn, Elisa A

“…Recruitment of neutrophils to the heart following acute myocardial infarction (MI) initiates inflammation and contributes to adverse post-infarct left…”
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Spironolactone Depletes the XPB Protein and Inhibits DNA Damage Responses in UVB-Irradiated Human Skin by Kemp, Michael G., Krishnamurthy, Smita, Kent, Michael N., Schumacher, David L., Sharma, Priyanka, Excoffon, Katherine J.D.A., Travers, Jeffrey B.

“…UVB wavelengths of light induce the formation of photoproducts in genomic DNA that are potentially mutagenic and detrimental to epidermal cell function. The…”
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MEOX1: a novel druggable target that orchestrates the activation of fibroblasts in cardiac fibrosis by Schumacher, David, Peisker, Fabian, Kramann, Rafael

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miR155 Deficiency Reduces Myofibroblast Density but Fails to Improve Cardiac Function after Myocardial Infarction in Dyslipidemic Mouse Model by Schumacher, David, Curaj, Adelina, Simsekyilmaz, Sakine, Schober, Andreas, Liehn, Elisa A., Mause, Sebastian F.

“…Myocardial infarction remains the most common cause of heart failure with adverse remodeling. MicroRNA (miR)155 is upregulated following myocardial infarction…”
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Germany's first Total Diet Study - Occurrence of non-dioxin-like polychlorinated biphenyls and polybrominated diphenyl ethers in foods by Stadion, Mandy, Blume, Katrin, Hackethal, Christin, Lüth, Anja, Schumacher, David M., Lindtner, Oliver, Sarvan, Irmela

“…The occurrence of persistent organic pollutants like polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in food represents a public…”
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Endogenous Modulation of Extracellular Matrix Collagen during Scar Formation after Myocardial Infarction by Schumacher, David, Curaj, Adelina, Staudt, Mareike, Simsekyilmaz, Sakine, Kanzler, Isabella, Boor, Peter, Klinkhammer, Barbara Mara, Li, Xiaofeng, Bucur, Octavian, Kaabi, Adnan, Xu, Yichen, Zheng, Huabo, Nilcham, Pakhwan, Schuh, Alexander, Rusu, Mihaela, Liehn, Elisa A

“…Myocardial infarction is remains the leading cause of death in developed countries. Recent data show that the composition of the extracellular matrix might…”
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Breast Cancer Stem Cells Upregulate IRF6 in Stromal Fibroblasts to Induce Stromagenesis by Muralidharan, Harshini, Hansen, Thomas, Steinle, Anja, Schumacher, David, Stickeler, Elmar, Maurer, Jochen

“…The microenvironment of a cancer stem cell (CSC) niche is often found in coexistence with cancer-associated fibroblasts (CAFs). Here, we show the first…”
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Effect of Helicobacter pylori on marginal ulcer and stomal stenosis after Roux-en- Y gastric bypass by Rawlins, Logan, M.D, Rawlins, Melissa P., M.P.A., P.A.-C, Brown, Carey C., M.D., F.A.C.S, Schumacher, David L., M.D., F.A.C.S

“…Abstract Background Conflicting data have been published regarding whether Helicobacter pylori (HP) positivity is associated with increased complication rates…”
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A neutralizing IL-11 antibody reduces vessel hyperplasia in a mouse carotid artery wire injury model by Schumacher, David, Liehn, Elisa A., Nilcham, Pakhwan, Mayan, David Castaño, Rattanasopa, Chutima, Anand, Kaviya, Crespo-Avilan, Gustavo E., Hernandez-Resendiz, Sauri, Singaraja, Roshni R., Cook, Stuart A., Hausenloy, Derek J.

“…Vascular restenosis remains a major problem in patients with coronary artery disease (CAD) and peripheral artery disease (PAD). Neointimal hyperplasia, defined…”
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Mutagenicity of the mycotoxin alternariol in cultured mammalian cells by Brugger, Eva-Maria, Wagner, Jörg, Schumacher, David M., Koch, Karen, Podlech, Joachim, Metzler, Manfred, Lehmann, Leane

“…The mycotoxin alternariol (AOH) is an important contaminant of fruit and cereal products. Concern about exposure to low levels of AOH was raised after the…”
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Evaluation of Riboflavin Transporters as Targets for Drug Delivery and Theranostics by Bartmann, Lisa, Schumacher, David, von Stillfried, Saskia, Sternkopf, Marieke, Alampour-Rajabi, Setareh, van Zandvoort, Marc A M J, Kiessling, Fabian, Wu, Zhuojun

“…The retention and cellular internalization of drug delivery systems and theranostics for cancer therapy can be improved by targeting molecules. Since an…”
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Effect of elevated hemoglobin A1c in diabetic patients on complication rates after Roux-en- Y gastric bypass by Rawlins, Logan, M.D, Rawlins, Melissa P., M.P.A., P.A.-C, Brown, Carey C., M.D., F.A.C.S, Schumacher, David L., M.D., F.A.C.S

“…Abstract Background Little is known regarding the effect of chronic hyperglycemia, expressed by glycated hemoglobin, on the healing-related complication rates…”
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Phosphatidylserine Supplementation as a Novel Strategy for Reducing Myocardial Infarct Size and Preventing Adverse Left Ventricular Remodeling by Schumacher, David, Curaj, Adelina, Staudt, Mareike, Cordes, Franziska, Dumitraşcu, Andreea R, Rolles, Benjamin, Beckers, Christian, Soppert, Josefin, Rusu, Mihaela, Simsekyilmaz, Sakine, Kneizeh, Kinan, Ramachandra, Chrishan J A, Hausenloy, Derek J, Liehn, Elisa A

“…Phosphatidylserines are known to sustain skeletal muscle activity during intense activity or hypoxic conditions, as well as preserve neurocognitive function in…”
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Apolipoprotein E4 Is Associated with Right Ventricular Dysfunction in Dilated Cardiomyopathy—An Animal and In-Human Comparative Study by Diaconu, Rodica, Schaaps, Nicole, Afify, Mamdouh, Boor, Peter, Cornelissen, Anne, Florescu, Roberta A., Simsekyilmaz, Sakine, El-Khoury, Teddy, Schumacher, David, Ioana, Mihai, Streata, Ioana, Militaru, Constantin, Donoiu, Ionut, Vogt, Felix, Liehn, Elisa A.

“…ApoE abnormality represents a well-known risk factor for cardiovascular diseases. Beyond its role in lipid metabolism, novel studies demonstrate a complex…”
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