Search Results - "SCHULTZ, R. M"

BRD4 regulates Nanog expression in mouse embryonic stem cells and preimplantation embryos by Liu, W, Stein, P, Cheng, X, Yang, W, Shao, N-Y, Morrisey, E E, Schultz, R M, You, J

“…Bromodomain-containing protein 4 (BRD4) is an important epigenetic reader implicated in the pathogenesis of a number of different cancers and other diseases…”
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The molecular foundations of the maternal to zygotic transition in the preimplantation embryo by Schultz, Richard M

“…The maternal to zygotic transition is the first major transition that occurs following fertilization, and entails a dramatic reprogramming of gene expression…”
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Differential Effects of Culture on Imprinted H19 Expression in the Preimplantation Mouse Embryo by DOHERTY, A. S, MANN, M. R. W, TREMBLAY, K. D, BARTOLOMEI, M. S, SCHULTZ, R. M

“…The H19 gene is imprinted with preferential expression from the maternal allele. The putative imprinting control region for this locus is hypermethylated on…”
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HDAC1 and HDAC2 in mouse oocytes and preimplantation embryos: Specificity versus compensation by Ma, P, Schultz, R M

“…Oocyte and preimplantation embryo development entail dynamic changes in chromatin structure and gene expression, which are regulated by a number of maternal…”
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Apoptosis during mouse blastocyst formation: evidence for a role for survival factors including transforming growth factor alpha by BRISON, D. R, SCHULTZ, R. M

“…Mouse blastocysts undergo cell death in the inner cell mass (ICM) as a normal feature of development, but little is known as to how this event is regulated or…”
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Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference by Svoboda, P, Stein, P, Hayashi, H, Schultz, R M

“…Specific mRNA degradation mediated by double-stranded RNA (dsRNA), which is termed RNA interference (RNAi), is a useful tool with which to study gene function…”
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Apolipoprotein E genotype and memory in the sixth decade of life by SCHULTZ, M. R, LYONS, M. J, FRANZ, C. E, GRANT, M. D, BOAKE, C, JACOBSON, K. C, XIAN, H, SCHELLENBERG, G. D, EISEN, S. A, KREMEN, W. S

“…Virtually all adult studies of APOE genotypes and cognition have included individuals over 60. In older adults, epsilon 4 carriers may manifest greater…”
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Spontaneous activation of ovulated mouse eggs: time-dependent effects on M-phase exit, cortical granule exocytosis, maternal messenger ribonucleic acid recruitment, and inositol 1,4,5-trisphosphate sensitivity by XU, Z, ABBOTT, A, KOPF, G. S, SCHULTZ, R. M, DUCIBELLA, T

“…With increasing time after ovulation, mammalian eggs become more sensitive to agonists of activation in vitro or may undergo spontaneous activation in vivo. We…”
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Regulation of Zygotic Gene Activation in the Preimplantation Mouse Embryo: Global Activation and Repression of Gene Expression by Ma, J, Svoboda, P, Schultz, R M, Stein, P

“…Superimposed on the activation of the embryonic genome in the preimplantation mouse embryo is the formation of a transcriptionally repressive state during the…”
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Prophase I arrest and progression to metaphase I in mouse oocytes: comparison of resumption of meiosis and recovery from G2-arrest in somatic cells by Solc, Petr, Schultz, Richard M., Motlik, Jan

“…Mammalian oocytes are arrested at prophase I until puberty when luteinizing hormone (LH) induces resumption of meiosis of follicle-enclosed oocytes. Resumption…”
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Acquisition of meiotic competence in mouse oocytes: absolute amounts of p34(cdc2), cyclin B1, cdc25C, and wee1 in meiotically incompetent and competent oocytes by Kanatsu-Shinohara, M, Schultz, R M, Kopf, G S

“…M-Phase promoting factor (MPF) is a complex of p34(cdc2) and cyclin B. Results of previous studies in which relative mass amounts of these cell cycle…”
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Potential role of mitogen-activated protein kinase in pronuclear envelope assembly and disassembly following fertilization of mouse eggs by MOOS, J, VISCONTI, P. E, MOORE, G. D, SCHULTZ, R. M, KOPF, G. S

“…Changes in the activities of the p34cdc2/cyclin B complex and mitogen-activated protein (MAP) kinase were analyzed after insemination of mouse eggs in vitro…”
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Absence of MSY2 in Mouse Oocytes Perturbs Oocyte Growth and Maturation, RNA Stability, and the Transcriptome by MEDVEDEV, Sergey, HUA PAN, SCHULTZ, Richard M

“…Messenger RNA is remarkably stable during oocyte growth, thus enabling mRNAs to accumulate during the growth phase and thereby provide mRNAs that support early…”
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Butyrolactone I reversibly inhibits meiotic maturation of bovine oocytes, without influencing chromosome condensation activity by Kubelka, M, Motlik, J, Schultz, R.M, Pavlok, A

“…In this study, butyrolactone I (BL I), a potent and specific inhibitor of cyclin-dependent kinases, was shown to block germinal vesicle (GV) breakdown (GVBD)…”
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Expression of MSY2 in Mouse Oocytes and Preimplantation Embryos by JUNYING YU, HECHT, Norman B, SCHULTZ, Richard M

“…Translational control plays a central role during oocyte maturation and early embryogenesis, as these processes occur in the absence of transcription. MSY2, a…”
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Preimplantation development of mouse embryos in KSOM: augmentation by amino acids and analysis of gene expression by Ho, Y, Wigglesworth, K, Eppig, J J, Schultz, R M

“…Simplex optimization has generated several media that have improved the development of mouse preimplantation embryos in vitro. One objective of this study was…”
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Increased incidence of apoptosis in transforming growth factor α-deficient mouse blastocysts by BRISON, D. R, SCHULTZ, R. M

“…We previously demonstrated that exogenous transforming growth factor alpha (TGFalpha) reduces the incidence of apoptosis in mouse blastocysts that develop in…”
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Relationship between the Developmental Programs Controlling Nuclear and Cytoplasmic Maturation of Mouse Oocytes by Eppig, John J., Schultz, Richard M., O'Brien, Marilyn, Chesnel, Franck

“…This paper focuses on the relationship between the developmental programs that regulate nuclear and cytoplasmic maturation of mouse oocytes. As oocytes near…”
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Igf2r and Igf2 gene expression in androgenetic, gynogenetic, and parthenogenetic preimplantation mouse embryos : absence of regulation by genomic imprinting by LATHAM, K. E, DOHERTY, A. S, SCOTT, C. D, SCHULTZ, R. M

“…Genomic imprinting in mammals is believed to result from modifications to chromosomes during gametogenesis that inactivate the paternal or maternal allele. The…”
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Posttranscriptional Regulation of Cyclin A1 and Cyclin A2 During Mouse Oocyte Meiotic Maturation and Preimplantation Development by FUCHIMOTO, Dai-Ichiro, MIZUKOSHI, Aki, SCHULTZ, Richard M, SAKAI, Senkiti, AOKI, Fugaku

“…A shift from a meiotic cell cycle to a mitotic cell cycle occurs following fertilization. The molecular basis for this transition, however, is poorly…”
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