Search Results - "SCHRÖDER, Nadja"
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Potential Therapeutic Effects of Lipoic Acid on Memory Deficits Related to Aging and Neurodegeneration
Published in Frontiers in pharmacology (12-12-2017)“…The aging process comprises a series of organic alterations, affecting multiple systems, including the nervous system. Aging has been considered the main risk…”
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The Role of Ca 2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation
Published in CNS & neurological disorders drug targets (2023)“…It is believed that degenerative conditions that give rise to neurological diseases may share an abnormal influx of Ca , mainly through glutamate receptors…”
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The effects of acute exercise on memory of cognitively healthy seniors: A systematic review
Published in Archives of gerontology and geriatrics (01-03-2022)“…•Review article investigating the effects of exercise on memory.•Ten acute-effect RCTs were included.•Sample of 456 individuals between 60 and 95 years…”
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Editorial: The impacts of iron accumulation on cognitive impairments
Published in Frontiers in human neuroscience (27-04-2023)Get full text
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Effects of lipoic acid supplementation on age- and iron-induced memory impairment, mitochondrial DNA damage and antioxidant responses
Published in European journal of nutrition (01-10-2021)“…Purpose To investigate the effects of lipoic acid (LA) supplementation during adulthood combined with supplementation later in life or LA administration only…”
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Behavior, BDNF and epigenetic mechanisms in response to social isolation and social support in middle aged rats exposed to chronic stress
Published in Behavioural brain research (12-03-2023)“…Social deprivation can be stressful for group-living mammals. On the other hand, an amazing response of these animals to stress is seeking social contact to…”
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Iron Overload Impairs Autophagy: Effects of Rapamycin in Ameliorating Iron-Related Memory Deficits
Published in Molecular neurobiology (01-02-2020)“…Over the years, iron accumulation in specific brain regions has been observed in normal aging and related to the pathogenesis of neurodegenerative disorders…”
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Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2011)“…Generalized Social Anxiety Disorder (SAD) is one of the most common anxiety conditions with impairment in social life. Cannabidiol (CBD), one major…”
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Effects of the AMPAR Antagonist, Perampanel, on Cognitive Function in Rats Exposed to Neonatal Iron Overload
Published in Molecular neurobiology (02-05-2024)“…Iron accumulation has been associated with the pathogenesis of neurodegenerative diseases and memory decline. As previously described by our research group,…”
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Posttraining systemic administration of the histone deacetylase inhibitor sodium butyrate ameliorates aging-related memory decline in rats
Published in Behavioural brain research (01-08-2011)“…► Sodium butyrate ameliorated an aging-associated recognition memory deficit in rats. ► The memory-improving effect was produced by an injection given early…”
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Novel insights into mitochondrial molecular targets of iron-induced neurodegeneration: Reversal by cannabidiol
Published in Brain research bulletin (01-05-2018)“…•Iron overload increased relative mtDNA deletions in the hippocampus of adult rats.•Methylation and hydroxymethylation of hippocampal mtDNA were reduced by…”
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NEK1 Mutations Cause Short-Rib Polydactyly Syndrome Type Majewski
Published in American journal of human genetics (07-01-2011)“…Defects of ciliogenesis have been implicated in a wide range of human phenotypes and play a crucial role in signal transduction and cell-cycle coordination. We…”
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The G protein-coupled estrogen receptor (GPER) regulates recognition and aversively–motivated memory in male rats
Published in Neurobiology of learning and memory (01-10-2021)“…•The GPER agonist G1 enhances long-term recognition memory in male rats.•The GPER antagonist G15 impairs long-term recognition memory in male rats.•G1…”
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Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload
Published in Translational psychiatry (03-09-2018)“…Iron accumulation in the brain has been recognized as a common feature of both normal aging and neurodegenerative diseases. Cognitive dysfunction has been…”
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Role of brain iron accumulation in cognitive dysfunction: evidence from animal models and human studies
Published in Journal of Alzheimer's disease (01-01-2013)“…Over the last decades, studies from our laboratory and other groups using animal models have shown that iron overload, resulting in iron accumulation in the…”
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Cognitive enhancers: Focus on modulatory signaling influencing memory consolidation
Published in Pharmacology, biochemistry and behavior (01-08-2011)“…Biological research has unraveled many of the molecular and cellular mechanisms involved in the formation of long-lasting memory, providing new opportunities…”
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Temporary inactivation reveals an essential role of the dorsal hippocampus in consolidation of object recognition memory
Published in Neuroscience letters (11-09-2006)“…The role of the hippocampus in novel object recognition (NOR) memory remains controversial. Here we report the finding that the dorsal hippocampus is essential…”
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Long-term environmental modifications affect BDNF concentrations in rat hippocampus, but not in serum
Published in Behavioural brain research (17-10-2019)“…•Environmental enrichment or impoverishment may lead to cognitive alterations.•Cognitive alterations were followed by hippocampal BDNF and synaptophysin…”
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G protein‐coupled oestrogen receptor stimulation ameliorates iron‐ and ovariectomy‐induced memory impairments through the cAMP/PKA/CREB signalling pathway
Published in Journal of neuroendocrinology (01-10-2019)“…Iron accumulation in the brain has been associated with neurodegenerative disorders, and imaging studies in humans indicate that iron content in brain regions…”
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Specialized Cilia in Mammalian Sensory Systems
Published in Cells (Basel, Switzerland) (11-09-2015)“…Cilia and flagella are highly conserved and important microtubule-based organelles that project from the surface of eukaryotic cells and act as antennae to…”
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