Search Results - "SCHOEN, R. T"

Vaccination against Lyme Disease with Recombinant Borrelia burgdorferi Outer-Surface Lipoprotein A with Adjuvant by Steere, Allen C, Sikand, Vijay K, Meurice, François, Parenti, Dennis L, Fikrig, Erol, Schoen, Robert T, Nowakowski, John, Schmid, Christopher H, Laukamp, Sabine, Buscarino, Charles, Krause, David S

“…Lyme disease, which is caused by the tick-borne spirochete Borrelia burgdorferi, is now the most common vector-borne disease in the United States. 1 Since the…”
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The consequences of Overdiagnosis and overtreatment of Lyme disease : An observational study by REID, M. C, SCHOEN, R. T, EVANS, J, ROSENBERG, J. C, HORWITZ, R. I

“…The adverse consequences associated with overdiagnosis and overtreatment of Lyme disease, although previously recognized, have received inadequate attention…”
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The clinical evolution of Lyme arthritis by Steere, A C, Schoen, R T, Taylor, E

“…To determine the clinical evolution of Lyme arthritis, 55 patients who did not receive antibiotic therapy for erythema chronicum migrans were followed…”
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Mechanisms of nonsteroidal anti-inflammatory drug-induced gastric damage by Schoen, R T, Vender, R J

“…The effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on the gastric mucosa are well documented. The complex mechanisms of gastric damage, however, are…”
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The Lyme disease vaccine : Conception, development, and implementation by THANASSI, W. T, SCHOEN, R. T

“…In the past 20 years, remarkable strides have been made toward understanding and preventing Lyme disease in humans. In December 1998, the U.S. Food and Drug…”
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Safety and Immunogenicity of an Outer Surface Protein A Vaccine in Subjects with Previous Lyme Disease by Schoen, Robert T., Meurice, Francois, Brunet, Cristina M., Cretella, Stella, Krause, David S., Craft, Joe E., Fikrig, Erol

“…The safety and immunogenicity of a recombinant outer surface protein A (OspA) Lyme vaccine in patients previously diagnosed with Lyme disease was assessed in a…”
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Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice by Fikrig, Erol, Flavell, Richard A, Alexopoulou, Lena, Thomas, Venetta, Schnare, Markus, Lobet, Yves, Anguita, Juan, Schoen, Robert T, Medzhitov, Ruslan

“…The Lyme disease vaccine is based on the outer-surface lipoprotein (OspA) of the pathogen Borrelia burgdorferi, and 95% of vaccine recipients develop…”
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Differential Expression of Borrelia burgdorferi Genes during Erythema Migrans and Lyme Arthritis by Fikrig, Erol, Feng, Wen, Aversa, John, Schoen, Robert T., Flavell, Richard A.

“…Borrelia burgdorferi, the agent of Lyme disease, selectively expresses genes in the arthropod vector and mammalian host. Specific B. burgdorferi gene…”
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Borrelia burgdorferi enzyme-linked immunosorbent assay for discrimination of OspA vaccination from spirochete infection by ZHANG, Y.-Q, MATHIESEN, D, KOLBERT, C. P, ANDERSON, J, SCHOEN, R. T, FIKRIG, E, PERSING, D. H

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Safety and immunogenicity profile of a recombinant outer-surface protein a Lyme disease vaccine: Clinical trial of a 3-dose schedule at 0, 1, and 2 months by Schoen, Robert T., Sikand, Vijay K., Caldwell, Michael C., Van Hoecke, C., Gillet, Marc, Buscarino, Charles, Parenti, Dennis L.

“…This study compared the tolerability of a Lyme disease vaccine administered intramuscularly at 0 and 1 months with that of a vaccine administered at 0, 1, and…”
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Identification of Lyme disease by Schoen, R T

“…The identification of Lyme disease is an important, rewarding process. In early disease, the presence of EM, the geographic location of the patient, and the…”
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Successful parenteral penicillin therapy of established Lyme arthritis by Steere, A C, Green, J, Schoen, R T, Taylor, E, Hutchinson, G J, Rahn, D W, Malawista, S E

“…In a double-blind placebo-controlled trial carried out from 1980 to 1982, 20 patients with established Lyme arthritis were assigned treatment with 2.4 million…”
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Asymptomatic Infection with Borrelia burgdorferi by Steere, Allen C., Sikand, Vijay K., Schoen, Robert T., Nowakowski, John

“…The natural history of asymptomatic seroconversion to Borrelia burgdorferi has been unclear. We report here, on the basis of a post hoc assessment, the…”
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Antigen-specific suppression of type II collagen-induced arthritis by collagen-coupled spleen cells by Schoen, RT, Greene, MI, Trentham, DE

“…The induction of arthritis in Wistar-Lewis rats was suppressed by i.v. injections of spleen cells coupled to native type II collagen, beginning 14 days before…”
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EDITORIAL COMMENTARY: Better Laboratory Testing for Lyme Disease: No More Western Blot by Schoen, Robert T.

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Infectious arthritis and immune dysfunction by Schoen, R T

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Autoimmunity induced by type II collagen-coupled spleen cells by Schoen, R T, Mehlman, H, Trentham, D E, Perry, L, Greene, M I, David, J R

“…Reactivity to self was induced by injecting rats subcutaneously (s.c.) with spleen cells coupled to native homologous or heterologous type II collagens. Native…”
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Lyme disease by Evans, J, Schoen, R T

“…In 1992, reported Lyme disease cases increased, but the majority remained clustered in the northeast and midwest, and in California. The clinical syndromes…”
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Treatment of refractory chronic Lyme arthritis with arthroscopic synovectomy by Schoen, R T, Aversa, J M, Rahn, D W, Steere, A C

“…Of 20 patients who underwent arthroscopic synovectomy for refractory chronic Lyme arthritis of the knee, 16 (80%) had resolution of joint inflammation during…”
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Pathogenesis, diagnosis, manifestations, and treatment of Lyme disease by Schoen, R T

“…Progress in understanding the causation and immunopathogenesis of Lyme disease has continued in the past year. Only by studying the complex relationship…”
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