Search Results - "SCHNEERSON, RACHEL"

Toward a new vaccine for pertussis by Robbins, John B., Schneerson, Rachel, Kubler-Kielb, Joanna, Keith, Jerry M., Trollfors, Birger, Vinogradov, Evgeny, Shiloach, Joseph

“…To overcome the limitations of the current pertussis vaccines, those of limited duration of action and failure to induce direct killing of Bordetella pertussis…”
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The Vi Conjugate Typhoid Vaccine Is Safe, Elicits Protective Levels of IgG Anti-Vi, and Is Compatible with Routine Infant Vaccines by Thiem, Vu Dinh, Lin, Feng-Ying C, Canh, Do Gia, Son, Nguyen Hong, Anh, Dang Duc, Mao, Nguyen Duc, Chu, Chiayung, Hunt, Steven W, Robbins, John B, Schneerson, Rachel, Szu, Shousun C

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Synthesis, characterization, and immunogenicity in mice of Shigella sonnei O-specific oligosaccharide-core-protein conjugates by Robbins, John B, Kubler-Kielb, Joanna, Vinogradov, Evguenii, Mocca, Christopher, Pozsgay, Vince, Shiloach, Joseph, Schneerson, Rachel

“…Shigellosis, an enteric disease, is on the World Health Organization's priority prevention list. In one study, the Shigella sonnei O-specific polysaccharide…”
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A Newly Discovered Cholesteryl Galactoside from Borrelia burgdorferi by Ben-Menachem, Gil, Kubler-Kielb, Joanna, Coxon, Bruce, Yergey, Alfred, Schneerson, Rachel

“…Two major glycolipids, which comprise ≈36% of the total lipid mass from Borrelia burgdorferi, the etiological agent of Lyme disease, were investigated. We…”
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Effect of the nonreducing end of Shigella dysenteriae type 1 O-specific oligosaccharides on their immunogenicity as conjugates in mice by Pozsgay, Vince, Kubler-Kielb, Joanna, Schneerson, Rachel, Robbins, John B

“…Endemic and epidemic shigellosis, an acute invasive disease of the lower intestines, afflicts millions of people worldwide with an estimated one million…”
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Preparation, characterization, and immunogenicity in mice of a recombinant influenza H5 hemagglutinin vaccine against the avian H5N1 A/Vietnam/1203/2004 influenza virus by Biesova, Zuzana, Miller, Mark A, Schneerson, Rachel, Shiloach, Joseph, Green, Kim Y, Robbins, John B, Keith, Jerry M

“…Abstract Production of influenza vaccines requires a minimum of 6 months after the circulating strain is isolated and the use of infectious viruses. The…”
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Capsular polysaccharide vaccine for Group B Neisseria meningitidis, Escherichia coli K1, and Pasteurella haemolytica A2 by Robbins, John B, Schneerson, Rachel, Xie, Guilin, Åke-Hanson, Lars, Miller, Mark A

“…We reviewed the literature that is the basis for our proposal that (2→8)-α-Neu5Ac conjugates will be safe and effective vaccines for Group B meningococci…”
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Oligosaccharide conjugates of Bordetella pertussis and bronchiseptica induce bactericidal antibodies, an addition to pertussis vaccine by Kubler-Kielb, Joanna, Vinogradov, Evgeny, Lagergård, Teresa, Ginzberg, Ariel, King, Jerry D, Preston, Andrew, Maskell, Duncan J, Pozsgay, Vince, Keith, Jerry M, Robbins, John B, Schneerson, Rachel

“…Pertussis is a highly contagious respiratory disease that is especially dangerous for infants and children. Despite mass vaccination, reported pertussis cases…”
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Synthesis and antigenicity of BBGL-2 glycolipids of Borrelia burgdorferi, the causative agent of Lyme disease by Pozsgay, Vince, Kubler-Kielb, Joanna, Coxon, Bruce, Marques, Adriana, Robbins, John B., Schneerson, Rachel

“…Borrelia burgdorferi is the etiological agent for Lyme disease (LD), the most common vector borne disease in the United States. There is no human vaccine…”
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Long-lasting and transmission-blocking activity of antibodies to Plasmodium falciparum elicited in mice by protein conjugates of Pfs25 by Kubler-Kielb, Joanna, Majadly, Fathy, Wu, Yimin, Narum, David L, Guo, Chunyan, Miller, Louis H, Shiloach, Joseph, Robbins, John B, Schneerson, Rachel

“…Malaria is a leading cause of morbidity and mortality, estimated to cause >1 million childhood deaths annually. Plasmodium falciparum causes the most severe…”
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Pre- and postexposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsule by Chen, Zhaochun, Schneerson, Rachel, Lovchik, Julie, Lyons, C. Rick, Zhao, Huaying, Dai, Zhongdong, Kubler-Kielb, Joanna, Leppla, Stephen H., Purcell, Robert H.

“…One of the two essential virulence factors of Bacillus anthracis is the poly-γ-D-glutamic acid (γDPGA) capsule. Five γDPGA-specific antibody antigen-binding…”
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Phase 1 Study of a Recombinant Mutant Protective Antigen of Bacillus anthracis by Bellanti, Joseph A, Lin, Feng-Ying C, Chu, Chiayung, Shiloach, Joseph, Leppla, Stephen H, Benavides, German A, Karpas, Arthur, Moayeri, Mahtab, Guo, Chunyan, Robbins, John B, Schneerson, Rachel

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bicomponent Plasmodium falciparum investigational vaccine composed of protein-peptide conjugates by Kubler-Kielb, Joanna, Majadly, Fathy, Biesova, Zuzana, Mocca, Christopher P, Guo, Chunyan, Nussenzweig, Ruth, Nussenzweig, Victor, Mishra, Satish, Wu, Yimin, Miller, Louis H, Keith, Jerry M, Liu, Teh-Yung, Robbins, John B, Schneerson, Rachel

“…There is yet no licensed vaccine against malaria, a serious human disease affecting mostly children, with an annual death rate of about one million. Plasmodia,…”
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Poly(γ-D-Glutamic Acid) Protein Conjugates Induce IgG Antibodies in Mice to the Capsule of Bacillus anthracis: A Potential Addition to the Anthrax Vaccine by Schneerson, Rachel, Kubler-Kielb, Joanna, Liu, Teh-Yung, Dai, Zhong-Dong, Leppla, Stephen H., Yergey, Alfred, Backlund, Peter, Shiloach, Joseph, Majadly, Fathy, Robbins, John B.

“…Both the protective antigen (PA) and the poly(γ-D-glutamic acid) capsule (γDPGA) are essential for the virulence of Bacillus anthracis. A critical level of…”
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Persistent Efficacy of Vi Conjugate Vaccine against Typhoid Fever in Young Children by Lin, Feng Ying C, Lanh, Mai Ngoc, Thanh, Tran Cong, Bryla, Dolores A, Van Bay, Phan, Chu, Chiayung, Ho, Vo Anh, Schiloach, Joseph, Robbins, John B, Schneerson, Rachel, Szu, Shousun C

“…To the Editor: The limitations of the three licensed typhoid vaccines that precluded their use in children younger than five years old have been overcome by a…”
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Saccharides cross-reactive with Bacillus anthracis spore glycoprotein as an anthrax vaccine component by Kubler-Kielb, Joanna, Vinogradov, Evgeny, Hu, Haijing, Leppla, Stephen H, Robbins, John B, Schneerson, Rachel

“…Bacillus anthracis is a spore-forming bacterium that causes anthrax in humans and in other mammals. The glycoprotein BclA (Bacillus collagen-like protein of…”
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Protein Conjugates of Synthetic Saccharides Elicit Higher Levels of Serum IgG Lipopolysaccharide Antibodies in Mice than Do Those of the O-Specific Polysaccharide from Shigella dysenteriae Type 1 by Pozsgay, Vince, Chu, Chiayung, Pannell, Lewis, Wolfe, Jennifer, Robbins, John B., Schneerson, Rachel

“…Our development of vaccines to prevent shigellosis is based on the hypothesis that a critical (protective) level of serum IgG to the O-specific polysaccharide…”
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The structure of the Escherichia coli O148 lipopolysaccharide core region and its linkage to the O-specific polysaccharide by Kubler-Kielb, Joanna, Lai, Wen-Tzu, Schneerson, Rachel, Vinogradov, Evgeny

“…Recently it was demonstrated that Shigella dysenteriae type 1, a cause of severe dysentery epidemics, gained its O-specific polysaccharide (O-SP) from…”
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Additional Conjugation Methods and Immunogenicity of Bacillus anthracis Poly-γ-D-Glutamic Acid-Protein Conjugates by Kubler-Kielb, Joanna, Liu, Teh-Yung, Mocca, Christopher, Majadly, Fathy, Robbins, John B, Schneerson, Rachel

“…The capsule of Bacillus anthracis, composed of poly-γ-D-glutamic acid (γDPGA), is an essential virulence factor of B. anthracis. The capsule inhibits innate…”
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Evaluation of Serum Bactericidal Antibody Assays for Haemophilus influenzae Serotype a by Rouphael, Nadine G, Satola, Sarah, Farley, Monica M, Rudolph, Karen, Schmidt, Daniel S, Gomez-de-León, Patricia, Robbins, John B, Schneerson, Rachel, Carlone, George M, Romero-Steiner, Sandra

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