Search Results - "SCHMITZ, P. J"

Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency by Diekman, E F, Visser, G, Schmitz, J P J, Nievelstein, R A J, de Sain-van der Velden, M, Wardrop, M, Van der Pol, W L, Houten, S M, van Riel, N A W, Takken, T, Jeneson, J A L

“…Rhabdomyolysis is common in very long-chain acyl-CoA dehydrogenase deficiency (VLCADD) and other metabolic myopathies, but its pathogenic basis is poorly…”
Get full text

Unchanged muscle fiber conduction velocity relates to mild acidosis during exhaustive bicycling by Schmitz, J. P. J., van Dijk, J. P., Hilbers, P. A. J., Nicolay, K., Jeneson, J. A. L., Stegeman, D. F.

“…Muscle fiber conduction velocity (MFCV) has often been shown to decrease during standardized fatiguing isometric contractions. However, several studies have…”
Get full text

Prediction of muscle energy states at low metabolic rates requires feedback control of mitochondrial respiratory chain activity by inorganic phosphate by Schmitz, Joep P J, Jeneson, Jeroen A L, van Oorschot, Joep W M, Prompers, Jeanine J, Nicolay, Klaas, Hilbers, Peter A J, van Riel, Natal A W

“…The regulation of the 100-fold dynamic range of mitochondrial ATP synthesis flux in skeletal muscle was investigated. Hypotheses of key control mechanisms were…”
Get full text

NO oxidation over supported Pt: Impact of precursor, support, loading, and processing conditions evaluated via high throughput experimentation by Schmitz, P.J., Kudla, R.J., Drews, A.R., Chen, A.E., Lowe-Ma, C.K., McCabe, R.W., Schneider, W.F., Goralski, C.T.

“…This work summarizes the development and validation of a high throughput approach for automated design, synthesis, screening, and statistical analysis of…”
Get full text

Reactively sputtered MoO3 films for ammonia sensing by PRASAD, A. K, GOUMA, P. I, KUBINSKI, D. J, VISSER, J. H, SOLTIS, R. E, SCHMITZ, P. J

“…Authors report the gas-sensing properties of ion-beam sputter deposited MoO3 thin-films. The change in the DC conductivity was measured in dry N2 with 10% O2…”
Get full text

31P MR spectroscopy and computational modeling identify a direct relation between Pi content of an alkaline compartment in resting muscle and phosphocreatine resynthesis kinetics in active muscle in humans by van Oorschot, Joep W M, Schmitz, Joep P J, Webb, Andrew, Nicolay, Klaas, Jeneson, Jeroen A L, Kan, Hermien E

“…The assessment of mitochondrial properties in skeletal muscle is important in clinical research, for instance in the study of diabetes. The gold standard to…”
Get full text

Varying Ti-6Al-4V surface roughness induces different early morphologic and molecular responses in MG63 osteoblast-like cells by Kim, H. J., Kim, S. H., Kim, M. S., Lee, E. J., Oh, H. G., Oh, W. M., Park, S. W., Kim, W. J., Lee, G. J., Choi, N. G., Koh, J. T., Dinh, D. B., Hardin, R. R., Johnson, K., Sylvia, V. L., Schmitz, J. P., Dean, D. D.

“…Osteoblast response to Ti implants depends not only on the chemistry of the implant but also on the physical properties of the implant surface, such as…”
Get full text

Kinetic Modeling of Saccharomyces cerevisiae Central Carbon Metabolism: Achievements, Limitations, and Opportunities by Lao-Martil, David, Verhagen, Koen J A, Schmitz, Joep P J, Teusink, Bas, Wahl, S Aljoscha, van Riel, Natal A W

“…Central carbon metabolism comprises the metabolic pathways in the cell that process nutrients into energy, building blocks and byproducts. To unravel the…”
Get full text

Silencing of glycolysis in muscle: experimental observation and numerical analysis by Schmitz, Joep P. J., Van Riel, Natal A. W., Nicolay, Klaas, Hilbers, Peter A. J., Jeneson, Jeroen A. L.

“…The longstanding problem of rapid inactivation of the glycolytic pathway in skeletal muscle after contraction was investigated using 31 P NMR spectroscopy and…”
Get full text

Reconstruction of bone using calcium phosphate bone cements: a critical review by Schmitz, J P, Hollinger, J O, Milam, S B

“…The calcium phosphate cements (CPCs) are rapidly emerging as a new technology in craniofacial surgery and will soon impact many areas of orthopedic and…”
Get more information

Oxidative stress and degenerative temporomandibular joint disease: a proposed hypothesis by Milam, S B, Zardeneta, G, Schmitz, J P

“…The molecular events that underlie degenerative temporomandibular joint diseases are poorly understood. Recent studies have provided evidence that a variety of…”
Get more information

The critical size defect as an experimental model for craniomandibulofacial nonunions by Schmitz, J P, Hollinger, J O

“…Little consistency has been manifest among investigators in choosing an appropriate experimental model for maxillofacial bone research. In an effort to develop…”
Get more information

Mechanism of formation of antiwear films from zinc dialkyldithiophosphates by Willermet, P.A., Dailey, D.P., Carter, R.O., Schmitz, P.J., Zhu, W.

“…Recently developed experimental techniques have allowed better characterization of lubricant-derived antiwear and antifriction surface films. These techniques…”
Get full text

Magnitude and control of mitochondrial sensitivity to ADP by Jeneson, Jeroen A L, Schmitz, Joep P J, van den Broek, Nicole M A, van Riel, Natal A W, Hilbers, Peter A J, Nicolay, Klaas, Prompers, Jeanine J

“…The transduction function for ADP stimulation of mitochondrial ATP synthesis in skeletal muscle was reconstructed in vivo and in silico to investigate the…”
Get more information

Molecular biology of temporomandibular joint disorders: proposed mechanisms of disease by Milam, S B, Schmitz, J P

“…The biologic processes of temporomandibular joint adaptation and disease are poorly understood. However, recent technologic advances have provided methods that…”
Get more information

Weld line morphology of injection molded polypropylene by Mielewski, D. F., Bauer, D. R., Schmitz, P. J., Van Oene, H.

“…The weakness of plastics at weld lines provides serious difficulties for the design and long term durability of injection molded parts. The goal of this work…”
Get full text

Combined in vivo and in silico investigations of activation of glycolysis in contracting skeletal muscle by Schmitz, J P J, Groenendaal, W, Wessels, B, Wiseman, R W, Hilbers, P A J, Nicolay, K, Prompers, J J, Jeneson, J A L, van Riel, N A W

“…The hypothesis was tested that the variation of in vivo glycolytic flux with contraction frequency in skeletal muscle can be qualitatively and quantitatively…”
Get more information

Elucidating yeast glycolytic dynamics at steady state growth and glucose pulses through kinetic metabolic modeling by Lao-Martil, David, Schmitz, Joep P.J., Teusink, Bas, van Riel, Natal A.W.

“…Microbial cell factories face changing environments during industrial fermentations. Kinetic metabolic models enable the simulation of the dynamic metabolic…”
Get full text

Pharmacokinetics of sertindole and dehydrosertindole in volunteers with normal or impaired renal function by WONG, S. L, MENACHERRY, S, MULFORD, D, SCHMITZ, P. J, LOCKE, C, GRANNEMAN, G. R

“…To study the effect of renal impairment on the pharmacokinetics of sertindole. A single 4 mg oral dose of sertindole was given to normal subjects (n = 6) and…”
Get full text

Early chronic lymphocytic leukemia: prognostic value of quantitative bone marrow MR imaging findings and correlation with hematologic variables by Lecouvet, F E, Vande Berg, B C, Michaux, L, Schmitz, P J, Malghem, J, Jamart, J, Maldague, B E, Ferrant, A, Michaux, J L

“…To determine the frequency of abnormal findings from quantitative bone marrow magnetic resonance (MR) imaging in patients with early-stage chronic lymphocytic…”
Get more information