Search Results - "SCHMITT, Claus"

Protective Actions of Anserine Under Diabetic Conditions by Peters, Verena, Calabrese, Vittorio, Forsberg, Elisabete, Volk, Nadine, Fleming, Thomas, Baelde, Hans, Weigand, Tim, Thiel, Christian, Trovato, Angela, Scuto, Maria, Modafferi, Sergio, Schmitt, Claus Peter

“…In rodents, carnosine treatment improves diabetic nephropathy, whereas little is known about the role and function of anserine, the methylated form of…”
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Carnosinase, diabetes mellitus and the potential relevance of carnosinase deficiency by Peters, Verena, Zschocke, Johannes, Schmitt, Claus P.

“…Carnosinase (CN1) is a dipeptidase, encoded by the CNDP1 gene , that degrades histidine-containing dipeptides, such as carnosine, anserine and homocarnosine…”
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Naturally Occurring Stable Calcium Isotope Ratios in Body Compartments Provide a Novel Biomarker of Bone Mineral Balance in Children and Young Adults by Shroff, Rukshana, Fewtrell, Mary, Heuser, Alexander, Kolevica, Ana, Lalayiannis, Alexander, McAlister, Louise, Silva, Selmy, Goodman, Nadine, Schmitt, Claus P, Biassoni, Lorenzo, Rahn, Anja, Fischer, Dagmar‐Christiane, Eisenhauer, Anton

“…ABSTRACT Serum calcium (Ca), bone biomarkers, and radiological imaging do not allow accurate evaluation of bone mineral balance (BMB), a key determinant of…”
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Balloon Filling Algorithm for Optimal Size of Balloon Expandable Prosthesis During Transcatheter Aortic Valve Replacement by Schymik, Gerhard, Radakovic, Milos, Bramlage, Peter, Schmitt, Claus, Tzamalis, Panagiotis

“…Aim is to report on the results of an optimized balloon filling algorithm and suggest a refinement of the implantation approach to maximize safety. Appropriate…”
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Practice of lipoprotein apheresis and short-term efficacy in children with homozygous familial hypercholesterolemia: Data from an international registry by Luirink, Ilse K., Hutten, Barbara A., Greber-Platzer, Susanne, Kolovou, Genovefa D., Dann, Eldad J., de Ferranti, Sarah D., Taylan, Christina, Bruckert, Eric, Saheb, Samir, Oh, Jun, Driemeyer, Joenna, Farnier, Michel, Pape, Lars, Schmitt, Claus P., Novoa, Francisco J., Maeser, Martin, Masana, Luis, Shahrani, Awad, Wiegman, Albert, Groothoff, Jaap W.

“…Homozygous familial hypercholesterolemia (hoFH) may cause life-threatening atherosclerotic cardiovascular disease in childhood. Lipoprotein apheresis (LA) is…”
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Biomarker research to improve clinical outcomes of peritoneal dialysis: consensus of the European Training and Research in Peritoneal Dialysis (EuTRiPD) network by Aufricht, Christoph, Beelen, Robert, Eberl, Matthias, Fischbach, Michel, Fraser, Donald, Jörres, Achim, Kratochwill, Klaus, LópezCabrera, Manuel, Rutherford, Peter, Schmitt, Claus-Peter, Topley, Nicholas, Witowski, Janusz

“…Peritoneal dialysis (PD) therapy substantially requires biomarkers as tools to identify patients who are at the highest risk for PD-related complications and…”
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Quantitative Histomorphometry of the Healthy Peritoneum by Schaefer, Betti, Bartosova, Maria, Macher-Goeppinger, Stephan, Ujszaszi, Akos, Wallwiener, Markus, Nyarangi-Dix, Joanne, Sallay, Peter, Burkhardt, Dorothea, Querfeld, Uwe, Pfeifle, Viktoria, Lahrmann, Bernd, Schwenger, Vedat, Wühl, Elke, Holland-Cunz, Stefan, Schaefer, Franz, Schmitt, Claus P.

“…The peritoneum plays an essential role in preventing abdominal frictions and adhesions and can be utilized as a dialysis membrane. Its physiological…”
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Efficacy and safety of lipoprotein apheresis in children with homozygous familial hypercholesterolemia: A systematic review by Luirink, Ilse K., Determeijer, Jim, Hutten, Barbara A., Wiegman, Albert, Bruckert, Eric, Schmitt, Claus P., Groothoff, Jaap W.

“…Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder that may cause life-threatening cardiovascular disease (CVD) at childhood. Marginal…”
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SGLT2 Inhibition by Intraperitoneal Dapagliflozin Mitigates Peritoneal Fibrosis and Ultrafiltration Failure in a Mouse Model of Chronic Peritoneal Exposure to High-Glucose Dialysate by Balzer, Michael S, Rong, Song, Nordlohne, Johannes, Zemtsovski, Jan D, Schmidt, Sonja, Stapel, Britta, Bartosova, Maria, von Vietinghoff, Sibylle, Haller, Hermann, Schmitt, Claus P, Shushakova, Nelli

“…Peritoneal dialysis (PD) is limited by glucose-mediated peritoneal membrane (PM) fibrosis, angiogenesis, and ultrafiltration failure. Influencing PM integrity…”
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miR-21 Promotes Fibrogenesis in Peritoneal Dialysis by Lopez-Anton, Melisa, Lambie, Mark, Lopez-Cabrera, Manuel, Schmitt, Claus P, Ruiz-Carpio, Vicente, Bartosova, Maria, Schaefer, Betti, Davies, Simon, Stone, Timothy, Jenkins, Robert, Taylor, Philip R, Topley, Nicholas, Bowen, Timothy, Fraser, Donald

“…Peritoneal dialysis (PD) is a life-saving form of renal replacement therapy for those with end-stage kidney disease. Mesothelial cells (MCs) line the…”
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Carnosine Catalyzes the Formation of the Oligo/Polymeric Products of Methylglyoxal by Weigand, Tim, Singler, Benjamin, Fleming, Thomas, Nawroth, Peter, Klika, Karel D., Thiel, Christian, Baelde, Hans, Garbade, Sven F., Wagner, Andreas H., Hecker, Markus, Yard, Benito A., Amberger, Albert, Zschocke, Johannes, Schmitt, Claus P., Peters, Verena

“…Background/Aims: Reactive dicarbonyl compounds, such as methylglyoxal (MG), contribute to diabetic complications. MG-scavenging capacities of carnosine and…”
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Clinical Trials on Diabetic Nephropathy: A Cross-Sectional Analysis by Modafferi, Sergio, Ries, Markus, Calabrese, Vittorio, Schmitt, Claus. P., Nawroth, Peter, Kopf, Stefan, Peters, Verena

“…Introduction Treatment options and decisions are often based on the results of clinical trials. We have evaluated the public availability of results from…”
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Cardiovascular Outcome of Pediatric Patients With Bi-Allelic (Homozygous) Familial Hypercholesterolemia Before and After Initiation of Multimodal Lipid Lowering Therapy Including Lipoprotein Apheresis by Taylan, Christina, Driemeyer, Joenna, Schmitt, Claus P., Pape, Lars, Büscher, Rainer, Galiano, Matthias, König, Jens, Schürfeld, Carsten, Spitthöver, Ralf, Versen, Axel, Koziolek, Michael, Marsen, Tobias A., Stein, Holger, Schaefer, Juergen R., Heibges, Andreas, Klingel, Reinhard, Oh, Jun, Weber, Lutz T., Klaus, Günter

“…Twenty-four patients with bi-allelic familial hypercholesterolemia commencing chronic lipoprotein apheresis (LA) at a mean age of 8.5 ± 3.1 years were analysed…”
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Biocompatible Peritoneal Dialysis: The Target Is Still Way Off by Bartosova, Maria, Schmitt, Claus Peter

“…Peritoneal dialysis (PD) is a cost-effective, home-based therapy for patients with end-stage renal disease achieving similar outcome as compared to…”
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Patient-Specific Identification of Atrial Flutter Vulnerability-A Computational Approach to Reveal Latent Reentry Pathways by Loewe, Axel, Poremba, Emanuel, Oesterlein, Tobias, Luik, Armin, Schmitt, Claus, Seemann, Gunnar, Dössel, Olaf

“…Atypical atrial flutter (AFlut) is a reentrant arrhythmia which patients frequently develop after ablation for atrial fibrillation (AF). Indeed, substrate…”
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Clinical impact of a new left bundle branch block following TAVI implantation: 1-year results of the TAVIK cohort by Schymik, Gerhard, Tzamalis, Panagiotis, Bramlage, Peter, Heimeshoff, Martin, Würth, Alexander, Wondraschek, Rainer, Gonska, Bernd-Dieter, Posival, Herbert, Schmitt, Claus, Schröfel, Holger, Luik, Armin

“…Background Compared with surgical aortic valve replacement, transcatheter aortic valve implantation (TAVI) is associated with a higher risk of developing a new…”
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Knock‐out of dipeptidase CN2 in human proximal tubular cells disrupts dipeptide and amino acid homeostasis and para‐ and transcellular solute transport by Pfeffer, Tilman, Krug, Susanne M., Kracke, Tamara, Schürfeld, Robin, Colbatzky, Florian, Kirschner, Philip, Medert, Rebekka, Freichel, Marc, Schumacher, Dagmar, Bartosova, Maria, Zarogiannis, Sotiris G., Muckenthaler, Martina U., Altamura, Sandro, Pezer, Silvia, Volk, Nadine, Schwab, Constantin, Duensing, Stefan, Fleming, Thomas, Heidenreich, Elena, Zschocke, Johannes, Hell, Rüdiger, Poschet, Gernot, Schmitt, Claus P., Peters, Verena

“…Aim Although of potential biomedical relevance, dipeptide metabolism has hardly been studied. We found the dipeptidase carnosinase‐2 (CN2) to be abundant in…”
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Bicarbonate buffered peritoneal dialysis fluid upregulates angiopoietin-1 and promotes vessel maturation by Eich, Gwendolyn, Bartosova, Maria, Tischer, Christian, Wlodkowski, Tanja Tamara, Schaefer, Betti, Pichl, Sebastian, Kraewer, Nicole, Ranchin, Bruno, Vondrak, Karel, Liebau, Max Christoph, Hackert, Thilo, Schmitt, Claus Peter

“…Ultrafiltration decline is a progressive issue for patients on chronic peritoneal dialysis (PD) and can be caused by peritoneal angiogenesis induced by PD…”
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A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice by Weigand, Tim, Colbatzky, Florian, Pfeffer, Tilman, Garbade, Sven F, Klingbeil, Kristina, Colbatzky, Florian, Becker, Michael, Zemva, Johanna, Bulkescher, Ruben, Schürfeld, Robin, Thiel, Christian, Volk, Nadine, Reuss, David, Hoffmann, Georg F, Freichel, Marc, Hecker, Markus, Poth, Tanja, Fleming, Thomas, Poschet, Gernot, Schmitt, Claus P, Peters, Verena

“…Carnosinase 1 (CN1) is encoded by the gene and degrades carnosine and anserine, two natural histidine-containing dipeptides. In vitro and in vivo studies…”
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Intrinsic carnosine metabolism in the human kidney by Peters, Verena, Klessens, Celine Q. F., Baelde, Hans J., Singler, Benjamin, Veraar, Kimberley A. M., Zutinic, Ana, Drozak, Jakub, Zschocke, Johannes, Schmitt, Claus P., de Heer, Emile

“…Histidine-containing dipeptides like carnosine and anserine have protective functions in both health and disease. Animal studies suggest that carnosine can be…”
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