Search Results - "SCHLAKE, T"

The nude gene and the skin by Schlake, T.

“…: The nude mutation has been known for a long time. Nevertheless, the gene responsible for the defect has been identified only recently. It encodes a…”
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Formation of regulator/target gene relationships during evolution by Schlake, T., Schorpp, M., Boehm, T.

“…The Foxn1-like forkhead/winged-helix transcription factor genes have been maintained in single copy throughout chordate evolution. Among other functions, Foxn1…”
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IGF-I Signalling Controls the Hair Growth Cycle and the Differentiation of Hair Shafts by Weger, Nicole, Schlake, Thomas

“…Mesenchymal–epithelial signalling between the dermal papilla and the hair matrix regulates cell proliferation and differentiation in mature hair follicles. The…”
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Genetic dissection of thymus development by Schorpp, M, Wiest, W, Egger, C, Hammerschmidt, M, Schlake, T, Boehm, T

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Predetermined chromosomal deletion encompassing the Nf-1 gene by SCHLAKE, T, SCHUPP, I, KUTSCHE, K, MINCHEVA, A, LICHTER, P, BOEHM, T

“…Complex chromosomal rearrangements (deletions, inversions, translocations) are a hallmark of human tumour cells. Yet, the generation of animal models for gross…”
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FGF signals specifically regulate the structure of hair shaft medulla via IGF-binding protein 5 by Schlake, Thomas

“…Reciprocal interactions between the dermal papilla and the hair matrix control proliferation and differentiation in the mature hair follicle. Analysis of…”
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mRNA as a Novel Treatment Strategy for Hereditary Spastic Paraplegia Type 5 by Hauser, Stefan, Poenisch, Marion, Schelling, Yvonne, Höflinger, Philip, Schuster, Stefanie, Teegler, Axel, Betten, Rabea, Gustafsson, Jan-Åke, Hübener-Schmid, Jeannette, Schlake, Thomas, Chevessier-Tünnesen, Frédéric, Horscroft, Nigel, Björkhem, Ingemar, Schöls, Ludger

“…Hereditary spastic paraplegia type 5 is a neurodegenerative disease caused by loss-of-function mutations in the CYP7B1 gene encoding the oxysterol…”
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Igfbp3 Modulates Cell Proliferation in the Hair Follicle by Weger, Nicole, Schlake, Thomas

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Use of Mutated FLP Recognition Target (FRT) Sites for the Exchange of Expression Cassettes at Defined Chromosomal Loci by Schlake, Thomas, Bode, Juergen

“…Using the FLP/FRT system for site-specific recombination and the wild-type recognition site (FRT) in conjunction with certain mutant FRT sites, it becomes…”
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Mating configurations in Schizosaccharomyces pombe strains of different geographical origins by Schlake, T. (Technische Univ. Braunschweig (Germany). Inst. fuer Genetik), Gutz, H

“…In genetic research with Schizosaccharomyces pombe the strains used are almost exclusively descendants of the clones originally isolated by Leupold. In the…”
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Separation of the hub from the shaft of a disposable epidural needle by SCHLAKE, P. T, PELEMAN, R. R, WINNIE, A. P

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Segmental Igfbp5 expression is specifically associated with the bent structure of zigzag hairs by Schlake, Thomas

“…The murine hair coat consists of four different hair types that are characterised by hair length, the number of medulla columns, and the presence and number of…”
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The transgeneticist's toolbox: novel methods for the targeted modification of eukaryotic genomes by Bode, J, Schlake, T, Iber, M, Schübeler, D, Seibler, J, Snezhkov, E, Nikolaev, L

“…Classical techniques for gene transfer into mammalian cells involve tedious screening procedures to identify transgenic clones or animals with the appropriate…”
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The Nude Gene Encodes a Sequence-Specific DNA Binding Protein with Homologs in Organisms that Lack an Anticipatory Immune System by Schlake, Thomas, Schorpp, Michael, Nehls, Michael, Boehm, Thomas

“…In the mouse, the product of the nude locus, Whn, is required for the keratinization of the hair shaft and the differentiation of epithelial progenitor cells…”
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Forkhead/winged‐helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of the Nude skin phenotype by Schlake, Thomas, Schorpp, Michael, Maul‐Pavicic, Andrea, Malashenko, A.M., Boehm, Thomas

“…The molecular characteristics of the nude phenotype (alopecia and thymic aplasia) in humans and rodents are unknown. The nude locus encodes Whn, a…”
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Major shifts in genomic activity accompany progression through different stages of the hair cycle by Schlake, Thomas, Beibel, Martin, Weger, Nicole, Boehm, Thomas

“…Hair follicles display a unique pattern of cyclic growth and regression involving cell proliferation, differentiation and migration. The molecular details of…”
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Genetically separable determinants of hair keratin gene expression by Schorpp, Michael, Schlake, Thomas, Kreamalmeyer, Darren, Allen, Paul M., Boehm, Thomas

“…The nude locus encodes Whn, a transcription factor of the forkhead/winged‐helix class. Mutations in Whn cause failure of differentiation of thymic epithelium…”
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Scaffold/matrix-attached regions: topological switches with multiple regulatory functions by Bode, J, Stengert-Iber, M, Kay, V, Schlake, T, Dietz-Pfeilstetter, A

“…The nuclear matrix or scaffold that can be prepared and investigated in vitro has an affinity for distinct topological forms of DNA and for sequences that…”
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Gene expression within a chromatin domain: the role of core histone hyperacetylation by Schlake, Thomas, Klehr-Wirth, Dagmar, Yoshida, Minoru, Beppu, Teruhiko, Bode, Juergen

“…Scaffold-attached regions (SAR elements) increase transcriptional rates for integrated but not episomal templates, and this effect can be potentiated by using…”
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Mating configurations in Schizosaccharomyces pombe strains of different geographic origins by SCHLAKE, T, GUTZ, H

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