Search Results - "SCHINDLER, CHARLES W."

Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive 'Bath Salts' Products by BAUMANN, Michael H, PARTILLA, John S, BRANDT, Simon D, TELLA, Srihari R, COZZI, Nicholas V, SCHINDLER, Charles W, LEHNER, Kurt R, THORNDIKE, Eric B, HOFFMAN, Alexander F, HOLY, Marion, ROTHMAN, Richard B, GOLDBERG, Steven R, LUPICA, Carl R, SITTE, Harald H

“…The abuse of psychoactive 'bath salts' containing cathinones such as 3,4-methylenedioxypyrovalerone (MDPV) is a growing public health concern, yet little is…”
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Conditioned stimulus effects on paired or alternative reinforcement depend on presentation duration: Implications for conceptualizations of craving by Ginsburg, Brett C., Nawrocik-Madrid, Acacia, Schindler, Charles W., Lamb, R. J.

“…Conditioned stimuli (CS) associated with alcohol ingestion are thought to play a role in relapse by producing a craving that in turn increases motivation to…”
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Effects of buprenorphine, methadone, and cariprazine on economic choice between remifentanil and food in squirrel monkeys by Amirali, Alishan S., Hecker, Jacquelin C., Figueroa-Monsanto, Hector L., Effinger, Devin P., Montoro, Rodrigo A., Jedema, Hank P., Vogt, Caleb D., Newman, Amy Hauck, Schindler, Charles W., Bradberry, Charles W.

“…We recently reported an economic choice task in which squirrel monkeys chose between differing amounts of remifentanil, a fast-acting opioid, or a food reward…”
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Effects of dopamine agonists and antagonists on locomotor activity in male and female rats by Schindler, Charles W., Carmona, Gilberto N.

“…Male and female Sprague–Dawley rats were treated with cocaine, the specific dopamine uptake inhibitor GBR 12909, the dopamine D1 agonist SKF 82958 or the…”
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Effects of cannabinoid receptor antagonists on maintenance and reinstatement of methamphetamine self-administration in rhesus monkeys by Schindler, Charles W., Panlilio, Leigh V., Gilman, Joanne P., Justinova, Zuzana, Vemuri, V. Kiran, Makriyannis, Alex, Goldberg, Steven R.

“…Cannabinoid receptor antagonists have shown some promise as treatments capable of reducing abuse and relapse to a number of abused drugs. In rodents, such…”
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Reinforcing effects of fentanyl analogs found in illicit drug markets by Maitland, Alexander D., McGriff, Shelby A., Glatfelter, Grant C., Schindler, Charles W., Baumann, Michael H.

“…Rationale The potent synthetic opioid fentanyl, and its analogs, continue to drive opioid-related overdoses. Although the pharmacology of fentanyl is well…”
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Neurochemical and Cardiovascular Effects of 4-Chloro Ring-Substituted Synthetic Cathinones in Rats by Chojnacki, Michael R, Thorndike, Eric B, Partilla, John S, Rice, Kenner C, Schindler, Charles W, Baumann, Michael H

“…Synthetic cathinones are a class of new psychoactive substances that display psychomotor stimulant properties, and novel cathinone analogs continue to emerge…”
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Reinforcing and neurochemical effects of the “bath salts” constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone (methylone) in male rats by Schindler, Charles W., Thorndike, Eric B., Goldberg, Steven R., Lehner, Kurt R., Cozzi, Nicholas V., Brandt, Simon D., Baumann, Michael H.

“…Rationale 3,4-Methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy- N -methylcathinone (methylone) are synthetic drugs found in so-called “bath salts”…”
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Choice between delayed food and immediate opioids in rats: treatment effects and individual differences by Panlilio, Leigh V., Secci, Maria E., Schindler, Charles W., Bradberry, Charles W.

“…Rationale Addiction involves maladaptive choice behavior in which immediate drug effects are valued more than delayed nondrug rewards. Objectives and methods…”
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Effects of stress modulation on morphine-induced conditioned place preferences and plasma corticosterone levels in Fischer, Lewis, and Sprague-Dawley rat strains by GRAKALIC, Ivana, SCHINDLER, Charles W, BAUMANN, Michael H, RICE, Kenner C, RILEY, Anthony L

“…There is a direct relationship between hypothalamic-pituitary-adrenal axis (HPA) reactivity and susceptibility to drug use in outbred rats. Specifically,…”
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Newly Developed Dopamine D 3 Receptor Antagonists, R -VK4-40 and R -VK4-116, Do Not Potentiate Cardiovascular Effects of Cocaine or Oxycodone in Rats by Jordan, Chloe J, Humburg, Bree A, Thorndike, Eric B, Shaik, Anver Basha, Xi, Zheng-Xiong, Baumann, Michael H, Newman, Amy Hauck, Schindler, Charles W

“…Opioid and cocaine abuse are major public health burdens. Existing medications for opioid use disorder are limited by abuse liability and side effects, whereas…”
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Synthetic cannabinoids found in “spice” products alter body temperature and cardiovascular parameters in conscious male rats by Schindler, Charles W., Gramling, Benjamin R., Justinova, Zuzana, Thorndike, Eric B., Baumann, Michael H.

“…•Physiological effects of abused synthetic cannabinoids were evaluated in rats.•All cannabinoids decreased body temperature.•Hypothermic effects of…”
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Blockade of Nicotine and Cannabinoid Reinforcement and Relapse by a Cannabinoid CB1-Receptor Neutral Antagonist AM4113 and Inverse Agonist Rimonabant in Squirrel Monkeys by Schindler, Charles W, Redhi, Godfrey H, Vemuri, Kiran, Makriyannis, Alexandros, Le Foll, Bernard, Bergman, Jack, Goldberg, Steven R, Justinova, Zuzana

“…Nicotine, the main psychoactive component of tobacco, and (-)-Δ(9)-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, play major roles…”
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Reinforcing effects of phenethylamine analogs found in dietary supplements by McGriff, Shelby A., Chojnacki, Michael R., Thorndike, Eric B., Rice, Kenner C., Baumann, Michael H., Schindler, Charles W.

“…Rationale Synthetic phenethylamine (PEA) analogs, such as β-methylphenethylamine (BMPEA) and N ,α-diethylphenethylamine (DEPEA), are often found in dietary…”
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Pharmacological mechanisms underlying the cardiovascular effects of the “bath salt” constituent 3,4‐methylenedioxypyrovalerone (MDPV) by Schindler, Charles W, Thorndike, Eric B, Suzuki, Masaki, Rice, Kenner C, Baumann, Michael H

“…Background and Purpose 3,4‐Methylenedioxypyrovalerone (MDPV) is a synthetic cathinone with stimulatory cardiovascular effects that can lead to serious medical…”
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Conditioned stimuli’s role in relapse: preclinical research on Pavlovian-Instrumental-Transfer by Lamb, R. J., Schindler, Charles W., Pinkston, Jonathan W.

“…Rationale and objective Pavlovian learning is central to many theories of addiction. In these theories, stimuli paired with drug ingestion become conditioned…”
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Ethanol-paired stimuli can increase reinforced ethanol responding by Lamb, R.J., Schindler, Charles W., Ginsburg, Brett C.

“…While ethanol-paired stimuli are frequently postulated to increase drinking motivation and thus increase ethanol responding and precipitate relapse, no study…”
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Amphetamine-like Neurochemical and Cardiovascular Effects of α -Ethylphenethylamine Analogs Found in Dietary Supplements by Schindler, Charles W, Thorndike, Eric B, Partilla, John S, Rice, Kenner C, Baumann, Michael H

“…Dietary supplements often contain additives not listed on the label, including -ethyl homologs of amphetamine such as , -diethylphenethylamine (DEPEA). Here,…”
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Newly Developed Dopamine D3 Receptor Antagonists, R-VK4-40 and R-VK4-116, Do Not Potentiate Cardiovascular Effects of Cocaine or Oxycodone in Rats by Jordan, Chloe J, Humburg, Bree A, Thorndike, Eric B, Shaik, Anver Basha, Xi, Zheng-Xiong, Baumann, Michael H, Newman, Amy Hauck, Schindler, Charles W

“…Opioid and cocaine abuse are major public health burdens. Existing medications for opioid use disorder are limited by abuse liability and side effects, whereas…”
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Economic choice between remifentanil and food in squirrel monkeys by Brown, Samantha O, Effinger, Devin P, Montoro, Rodrigo A, Daddaoua, Nabil, Justinova, Zuzana, Moerke, Megan J, Schindler, Charles W, Jedema, Hank P, Bradberry, Charles W

“…Traditional approaches for evaluating if compounds are reinforcing, and thus a risk for abuse, include preclinical self-administration procedures conducted in…”
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