Search Results - "SCHILZ, A. J"

Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells by KNIPPER, R, KUEHLCKE, K, ECKERT, H.-G, BAUM, C, SCHIEDLMEIER, B, HILDINGER, M, LINDEMANN, C, SCHILZ, A. J, FAUSER, A. A, FRUEHAUF, S, ZELLER, W. J, OSTERTAG, W

“…We describe the functional analysis of a novel retroviral vector, SF91m3, which was designed for improved expression of the in vivo selectable marker,…”
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MDR1 Gene Expression in NOD/SCID Repopulating Cells after Retroviral Gene Transfer under Clinically Relevant Conditions by Schilz, A.J., Schiedlmeier, B., Kühlcke, K., Fruehauf, S., Lindemann, C., Zeller, W.J., Grez, M., Fauser, A.A., Baum, C., Eckert, H.-G.

“…We have adapted a recently published protocol for retroviral gene transfer into hematopoietic cells [A. J. Schilz et al. (1998) Blood 92: 3163–3171] with…”
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FMEV vectors : both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells by HILDINGER, M, ECKERT, H.-G, SCHILZ, A. T, JOHN, T, OSTERTAG, W, BAUM, C

“…FMEV retroviral vectors combine the long terminal repeat of Friend mink cell focus-forming viruses with the 5' untranslated leader region of the murine…”
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Clinical scale production of an improved retroviral vector expressing the human multidrug resistance 1 gene (MDR1) by Eckert, H G, Kühlcke, K, Schilz, A J, Lindemann, C, Basara, N, Fauser, A A, Baum, C

“…Retroviral vectors are currently the most important and best characterized tools for ex vivo genetic modification of hematopoietic progenitor/stem cells. As a…”
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High Efficiency Gene Transfer to Human Hematopoietic SCID-Repopulating Cells Under Serum-Free Conditions by Schilz, Andrea J., Brouns, Gaby, Knöβ, Heike, Ottmann, Oliver G., Hoelzer, Dieter, Fauser, Axel A., Thrasher, Adrian J., Grez, Manuel

“…Stable gene transfer to human pluripotent hematopoietic stem cells (PHSCs) is an attractive strategy for the curative treatment of many genetic hematologic…”
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Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice by Schiedlmeier, Bernd, Schilz, Andrea J, Kühlcke, Klaus, Laufs, Stephanie, Baum, Christopher, Zeller, W Jens, Eckert, Hans-Georg, Fruehauf, Stefan

“…Myelosuppression is the main side effect of cancer chemotherapy. An improved rate of retroviral vector-mediated gene transfer to hematopoietic stem cells,…”
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Optimization of retroviral vector generation for clinical application by Schilz, Andrea J., Kühlcke, Klaus, Fauser, Axel A., Eckert, Hans-Georg

“…Background For many inherited and acquired diseases of the blood system, gene transfer into hematopoietic cells is a promising strategy to alleviate…”
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Analysis of retroviral mediated transgene expression after in vitro differentiation of mobilized human peripheral blood progenitor cells by Eckert, H.G., Lindemann, C., Schilz, A.J., Fauser, A.A., Baum, C., Kühlcke, K.

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High Efficiency Gene Transfer to Human Hematopoietic SCID-Repopulating Cells Under Serum-Free Conditions by Schilz, Andrea J., Brouns, Gaby, Knöβ, Heike, Ottmann, Oliver G., Hoelzer, Dieter, Fauser, Axel A., Thrasher, Adrian J., Grez, Manuel

“…Stable gene transfer to human pluripotent hematopoietic stem cells (PHSCs) is an attractive strategy for the curative treatment of many genetic hematologic…”
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Down-regulation of retroviral transgene expression during differentiation of progenitor-derived dendritic cells by Lindemann, Carsten, Schilz, Andrea J, Emons, Barbara, Baum, Christopher, Löw, Rainer, Fauser, Axel A, Kuehlcke, Klaus, Eckert, Hans-Georg

“…Objective. Hematopoietic progenitor cells are a promising source for generation of genetically modified dendritic cells. A prerequisite for using these cells…”
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