Search Results - "SCHIJNS, V. E. C. J"

Vaccine Immunopotentiators of the Future by Schijns, V E J C, Degen, W G J

“…Vaccine adjuvants or immunopotentiators comprise a diverse group of molecules or formulations. Despite a wealth of different candidates, there is a need for…”
Get full text

Immunotherapy of malignant gliomas using autologous and allogeneic tissue cells by Hofman, F M, Stathopoulos, A, Kruse, C A, Chen, T C, Schijns, V E J C

“…Immunotherapy of brain tumors is rapidly emerging as a potential clinical option [1-3]. The quality and magnitude of immune responses evoked by the new…”
Get more information

Vaccination of dogs with six different candidate leishmaniasis vaccines composed of a chimerical recombinant protein containing ribosomal and histone protein epitopes in combination with different adjuvants by Poot, J, Janssen, L.H.M, van Kasteren-Westerneng, T.J, van der Heijden-Liefkens, K.H.A, Schijns, V.E.J.C, Heckeroth, A

“…Abstract Chimerical protein “Q”, composed of antigenic ribosomal and histone sequences, in combination with live BCG is a promising canine leishmaniasis…”
Get full text

Human prophylactic vaccine adjuvants and their determinant role in new vaccine formulations by Pérez, O, Batista-Duharte, A, González, E, Zayas, C, Balboa, J, Cuello, M, Cabrera, O, Lastre, M, Schijns, V E J C

“…Adjuvants have been considered for a long time to be an accessory and empirical component of vaccine formulations. However, accumulating evidence of their…”
Get full text

Veterinary vaccine development from an industrial perspective by Heldens, J.G.M., Patel, J.R., Chanter, N., ten Thij, G.J., Gravendijck, M., Schijns, V.E.J.C., Langen, A., Schetters, Th.P.M.

“…Veterinary vaccines currently available in Europe and in other parts of the world are developed by the veterinary pharmaceutical industry. The development of a…”
Get full text

Vaccination with a preparation based on recombinant cysteine peptidases and canine IL-12 does not protect dogs from infection with Leishmania infantum by Poot, J., Spreeuwenberg, K., Sanderson, S.J., Schijns, V.E.C.J., Mottram, J.C., Coombs, G.H., Vermeulen, A.N.

“…Cysteine peptidases (CPs) have been implicated in various processes central to the pathogenicity of Leishmania parasites, and are thought to be key factors in…”
Get full text

Vaccine adjuvant technology: from theoretical mechanisms to practical approaches by Schijns, V E J C, Tangerås, A

“…Poorly immunogenic antigens depend on vaccine adjuvants to evoke an immune response. In addition, adjuvants largely determine the magnitude, quality, time of…”
Get more information

Expression of chicken interleukin-2 by turkey herpesvirus increases the immune response against Marek's disease virus but fails to increase protection against virulent challenge by Tarpey, I, Davis, P.J, Sondermeijer, P, Geffen, C. van, Verstegen, I, Schijns, V.E.J.C, Kolodsick, J, Sundick, R

“…As Marek's disease virus continues to evolve towards greater virulence, more efficacious vaccines will be required in the future. We expressed chicken…”
Get full text

Mouse hepatitis virus spike and nucleocapsid proteins expressed by adenovirus vectors protect mice against a lethal infection by Wesseling, John G, Godeke, Gert-Jan, Schijns, Virgil E. C. J, Prevec, Ludvik, Graham, Frank L, Horzinek, Marian C, Rottier, Peter J. M

“…1 Institute of Virology, Veterinary Faculty, Utrecht University, P.O. Box 80.165, 3508 TD Utrecht, The Netherlands and 2 Departments of Biology and Pathology,…”
Get full text

Response to "'Post-alum Adjuvants' May Reach Beyond Their Intended Purpose: The Clinical Development of TLR Agonists" by Schijns, VEJC, Degen, WGJ

Get full text

Antiviral activity of recombinant rat interferon gamma in immunologically impaired and immunosuppressed rats by Schijns, V.E.C.J, Borman, T.H, Schellekens, H, Horzinek, M.C

“…1 Institute of Virology, Veterinary Faculty, State University Utrecht, Yalelaan 1, 3508 TD Utrecht and 2 Primate Center TNO, P.O. Box 5815, 2280 HV Rijswijk,…”
Get full text

Immunoadjuvant activities of E. coli- and plasmid-expressed recombinant chicken IFN- α/ β, IFN- γ and IL-1 β in 1-day- and 3-week-old chickens by Schijns, Virgil E.C.J., Weining, Kirsten C., Nuijten, Piet, Rijke, Eric O., Staeheli, Peter

“…In the present study we assessed the capacity of recombinant E. coli- or plasmid-expressed chicken interferons (IFN) and chicken IL-1 β, to exert…”
Get full text

Vaccination of pigs against pseudorabies virus with plasmid DNA encoding glycoprotein D by Haagmans, Bart L, van Rooij, Eugene M.A, Dubelaar, Mark, Kimman, Tjeerd G, Horzinek, Marian C, Schijns, Virgil E.C.J, Bianchi, Andre T.J

“…We analysed the ability of a plasmid carrying the gene encoding glycoprotein D (gD) of pseudorabies virus (PRV) to induce humoral and cell-mediated immune…”
Get full text

Modulation of antiviral immune responses by exogenous cytokines: effects of tumour necrosis factor-alpha, interleukin-1 alpha, interleukin-2 and interferon-gamma on the immunogenicity of an inactivated rabies vaccine by Schijns, V.E.C.J, Claassen, I.J.T.M, Vermeulen, A.A, Horzinek, M.C, Osterhaus, A.D.M.E

“…In vivo administration of exogenous cytokines may influence elicited immune responses. and hence may change the efficacy of a vaccine. We investigated the…”
Get full text

Tumor necrosis factor alpha promotes replication and pathogenicity of rat cytomegalovirus by HAAGMANS, B. L, STALS, F. S, VAN DER MEIDE, P. H, BRUGGEMAN, C. A, HORZINEK, M. C, SCHIJNS, V. E. C. J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Tumour necrosis factor-α production during cytomegalovirus infection in immunosuppressed rats by HAAGMANS, B. L, VAN DEN EERTWEGH, A. J. M, CLAASSEN, E, HORZINEK, M. C, SCHIJNS, V. E. C. J

“…The production of tumour necrosis factor (TNF)-alpha, interleukin (IL)-1 and IL-6, all proinflammatory cytokines, was investigated in…”
Get full text

Tumour necrosis factor-α, interferon-γ and interferon-β exert antiviral activity in nervous tissue cells by SCHIJNS, V. E. C. J, VAN DER NEUT, R, HAAGMANS, B. L, BAR, D. R, SCHELLEKENS, H, HORZINEK, M. C

“…The individual and synergistic antiviral effects of cytokines released by infiltrating immune cells or by cells of the nervous system may play an important…”
Get full text

Molecular cloning of cat interleukin-12 by Schijns, V E, Wierda, C M, Vahlenkamp, T W, Horzinek, M C

Get full text

Suppression of rat cytomegalovirus replication by antibodies against gamma inteferon by HAAGMANS, B. L, VAN DER MEIDE, P. H, STALS, F. S, VAN DER EERTWEGH, A. J. M, CLAASSEN, E, BRUGGEMAN, C. A, HORZINEK, M. C, SCHIJNS, V. E. C. J

Get full text

Tumour necrosis factor-{alpha} production during cytomegalovirus infection in immunosuppressed rats by Haagmans, Bart L, van den Eertwegh, Alfons J. M, Claassen, Eric, Horzinek, Marian C, Schijns, Virgil E. C. J

“…1 Virology Division, Department of Infectious Diseases and Immunology, Veterinary Faculty, Utrecht University, Yalelaan 1, 3584 CL Utrecht and 2 Department of…”
Get full text