Search Results - "SCHERBAUM, W. A"

Self-monitoring of blood glucose in type 2 diabetes and long-term outcome: an epidemiological cohort study by Martin, S, Schneider, B, Heinemann, L, Lodwig, V, Kurth, H.-J, Kolb, H, Scherbaum, W. A

“…Aims/hypothesis The aim of this study was to obtain epidemiological data on self-monitoring of blood glucose (SMBG) in type 2 diabetes and to investigate the…”
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Molecular mechanisms of insulin resistance by Schinner, S., Scherbaum, W. A., Bornstein, S. R., Barthel, A.

“…Currently, we observe an epidemic expansion of diabetes mellitus. In subjects with Type 2 diabetes the resistance of fat, muscle and liver to insulin is the…”
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Age-dependent decline of β-cell function in type 1 diabetes after diagnosis: a multi-centre longitudinal study by Barker, A., Lauria, A., Schloot, N., Hosszufalusi, N., Ludvigsson, J., Mathieu, C., Mauricio, D., Nordwall, M., Van der Schueren, B., Mandrup-Poulsen, T., Scherbaum, W. A., Weets, I., Gorus, F. K., Wareham, N., Leslie, R. D., Pozzilli, P.

“…Aims C‐peptide secretion is currently the only available clinical biomarker to measure residual β‐cell function in type 1 diabetes. However, the natural…”
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BMI is an important driver of β-cell loss in type 1 diabetes upon diagnosis in 10 to 18-year-old children by Lauria, A, Barker, A, Schloot, N, Hosszufalusi, N, Ludvigsson, J, Mathieu, C, Mauricio, D, Nordwall, M, Van der Schueren, B, Mandrup-Poulsen, T, A Scherbaum, W, Weets, I, K Gorus, F, Wareham, N, D Leslie, R, Pozzilli, P

“…ObjectiveBody weight-related insulin resistance probably plays a role in progression to type 1 diabetes, but has an uncertain impact following diagnosis. In…”
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Human adipocytes secrete mineralocorticoid-releasing factors by Ehrhart-Bornstein, M, Lamounier-Zepter, V, Schraven, A, Langenbach, J, Willenberg, H.S, Barthel, A, Hauner, H, McCann, S.M, Scherbaum, W.A, Bornstein, S.R

“…Obesity has become an epidemic problem in western societies, contributing to metabolic diseases, hypertension, and cardiovascular disease. Overweight and…”
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Evidence for an exercise induced increase of TNF-α and IL-6 in marathon runners by Bernecker, C., Scherr, J., Schinner, S., Braun, S., Scherbaum, W. A., Halle, M.

“…Regular physical activity of moderate intensity improves cardiovascular risk factors including low‐grade inflammation. However, acute vigorous exercise such as…”
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Introducing a simplified approach to insulin therapy in type 2 diabetes: a comparison of two single-dose regimens of insulin glulisine plus insulin glargine and oral antidiabetic drugs by Lankisch, M.R, Ferlinz, K.C, Leahy, J.L, Scherbaum, W.A

“…To investigate whether the addition of a single bolus of insulin glulisine (glulisine), administered at either breakfast or main mealtime, in combination with…”
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Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules by Schinner, S, Ülgen, F, Papewalis, C, Schott, M, Woelk, A, Vidal-Puig, A, Scherbaum, W. A

“…Aims/hypothesis Adipocytes secrete signalling molecules that elicit responses from target cells, including pancreatic beta cells. Wnt signalling molecules have…”
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Adipocyte-derived products induce the transcription of the StAR promoter and stimulate aldosterone and cortisol secretion from adrenocortical cells through the Wnt-signaling pathway by Schinner, S, Willenberg, H.S, Krause, D, Schott, M, Lamounier-Zepter, V, Krug, A.W, Ehrhart-Bornstein, M, Bornstein, S.R, Scherbaum, W.A

“…Context: Obesity is associated with hypersecretion of cortisol and aldosterone and a high prevalence of arterial hypertension. At the cellular level, a direct…”
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Unconditioned and conditioned effects of intranasally administered insulin vs placebo in healthy men: a randomised controlled trial by Stockhorst, U., de Fries, D., Steingrueber, H.-J., Scherbaum, W. A.

“…Aims/hypothesis In humans, the intranasal route allows insulin to reach the brain while maintaining peripheral euglycaemia. Our aims were to examine acute…”
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Increased serum concentrations of adhesion molecules but not of chemokines in patients with Type 2 diabetes compared with patients with Type 1 diabetes and latent autoimmune diabetes in adult age: Action LADA 5 by Pham, M. N., Hawa, M. I., Roden, M., Schernthaner, G., Pozzilli, P., Buzzetti, R., Scherbaum, W. A., Seissler, J., Hunter, S., Leslie, R. D. G., Kolb, H., Schloot, N. C.

“…Diabet. Med. 29, 470–478 (2012) Aims  Systemic concentrations of adhesion molecules and chemokines are associated with increased risk of cardiovascular…”
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Titre and combination of ICA and autoantibodies to glutamic acid decarboxylase discriminate two clinically distinct types of latent autoimmune diabetes in adults (LADA) by LOHMANN, T, KELLNER, K, VERLOHREN, H.-J, KRUG, J, STEINDORF, J, SCHERBAUM, W. A, SEISSLER, J

“…ABSTRACT AIMS/HYPOTHESIS: This study aimed to define the immunological parameters which could be used to identify patients with the distinct metabolic features…”
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Subclinical hypothyroidism and the prevalence of the metabolic syndrome by Liu, C, Scherbaum, W A, Schott, M, Schinner, S

“…There is currently controversial data regarding the prevalence of MS among SCH patients. The aim of the study was to investigate the prevalence of MS in an…”
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Antibodies against glutamic acid decarboxylase: prevalence in neurological diseases by Meinck, H-M, Faber, L, Morgenthaler, N, Seissler, J, Maile, S, Butler, M, Solimena, M, DeCamilli, P, Scherbaum, WA

“…High prevalence of autoantibodies against glutamic acid decarboxylase (GAD-Ab) in stiff man syndrome (SMS) not only helps diagnosis, but also suggests immune…”
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Incidentally discovered pituitary lesions: high frequency of macroadenomas and hormone-secreting adenomas - results of a prospective study by FELDKAMP, J, SANTEN, R, HARMS, E, AULICH, A, MÖDDER, U, SCHERBAUM, W. A

“…OBJECTIVE With increasing use of computed tomography and magnetic resonance imaging, pituitary adenomas are being discovered incidentally with increasing…”
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Expression of Ob receptor in normal human adrenals : Differential regulation of adrenocortical and adrenomedullary function by leptin by GLASOW, A, HAIDAN, A, HILBERS, U, BREIDERT, M, GILLESPIE, J, SCHERBAUM, W. A, CHROUSOS, G. P, BORNSTEIN, S. R

“…The major effects of leptin, an adipostatic hormone produced in fat tissue, are exerted through the hypothalamic-pituitary-adrenal axis and the systemic…”
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Hypercortisolism caused by ritonavir associated inhibition of CYP 3A4 under inhalative glucocorticoid therapy. 2 case reports and a review of the literature by Bernecker, C, West, T B, Mansmann, G, Scherbaum, W A, Willenberg, H S

“…Recent in vitro and in vivo studies have shown a potent inhibition of cytochrome P450 CYP3A4 through human immune deficiency virus (HIV) protease inhibitors…”
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Islet enhancer vildagliptin: a powerful partner with metformin for the treatment of patients with type 2 diabetes by Scherbaum, W.A

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Epidemiology of complications and total treatment costs from diagnosis of Type 2 diabetes in Germany (ROSSO 4) by Martin, S, Schramm, W, Schneider, B, Neeser, K, Weber, C, Lodwig, V, Heinemann, L, Scherbaum, W A, Kolb, H

“…To determine the occurrence of complications and treatment costs in the first 6 years from diagnosis of Type 2 diabetes in the primary care level. The German…”
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Evidence for an exercise induced increase of TNF-[alpha] and IL-6 in marathon runners by Bernecker, C, Scherr, J, Schinner, S, Braun, S, Scherbaum, W. A, Halle, M

“…Regular physical activity of moderate intensity improves cardiovascular risk factors including low-grade inflammation. However, acute vigorous exercise such as…”
Get full text