Search Results - "SCHECTER, R. L"
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1
Characterization of 5-oxo-L-prolinase in normal and tumor tissues of humans and rats: a potential new target for biochemical modulation of glutathione
Published in Clinical cancer research (01-01-1998)“…5-Oxo-L-prolinase (5-OPase) is an enzyme of the gamma-glutamyl cycle involved in the synthesis and metabolism of glutathione (GSH), which is known to protect…”
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2
Relation of glutathione S-transferase alpha and mu isoforms to response to therapy in human breast cancer
Published in Clinical cancer research (01-05-1997)“…Glutathione S-transferase (GST) represents a multifunctional enzyme family consisting of four known cytosolic isoforms (alpha, mu, pi, and Phi) that detoxify a…”
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3
Expression of a rat glutathione-S-transferase complementary DNA in rat mammary carcinoma cells : impact upon alkylator-induced toxicity
Published in Cancer research (Chicago, Ill.) (15-10-1993)“…The role of glutathione-S-transferase (GST) in alkylator drug resistance has been studied in MatB rat mammary carcinoma cells. A series of GST transfectant…”
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4
In vivo reversal of doxorubicin resistance by a new tiapamil analog Ro11-2933
Published in The Journal of pharmacology and experimental therapeutics (01-03-1993)“…The effectiveness of a calcium antagonist analog Ro11-2933 to modulate doxorubicin (DOX) response in DOX-sensitive (WT) and -resistant (DOXr, 200-fold) cell…”
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5
Retrovirus-mediated gene transfer of rat glutathione S-transferase Yc confers alkylating drug resistance in NIH 3T3 mouse fibroblasts
Published in Cancer research (Chicago, Ill.) (15-08-1994)“…A major limitation to successful cancer treatment is the existence of drug resistance. While several mechanisms of drug resistance have now been well…”
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6
Modulation of glutathione by a cysteine pro-drug enhances in vivo tumor response
Published in The Journal of pharmacology and experimental therapeutics (01-03-1996)“…Glutathione (GSH) is known to play a role in cellular sensitivity to some chemotherapeutic agents and to radiation. Depletion of cellular glutathione increases…”
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7
Double antibody radioimmunoassay for monitoring metastatic breast cancer
Published in British journal of cancer (01-09-1988)“…We previously reported the production of a panel of murine monoclonal antibodies which recognize glycoproteins abnormally expressed in human breast tumours…”
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8
Modulation of Glutathione S-Transferase Alpha by Hepatitis B Virus and the Chemopreventive Drug Oltipraz
Published in The Journal of biological chemistry (27-10-2000)“…Persistent infection by hepatitis B virus (HBV) and exposure to chemical carcinogens correlates with the prevalence of hepatocellular carcinoma in endemic…”
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9
In vivo and in vitro mechanisms of drug resistance in a rat mammary carcinoma model
Published in Cancer research (Chicago, Ill.) (01-03-1991)“…Many in vitro tumor models have been examined to help understand the precise mechanisms responsible for drug resistance. The importance of these results in…”
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10
Evidence for genomic duplication of the glutathione transferase A3 gene in genus Rattus
Published in Molecular biology and evolution (01-02-2000)Get full text
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11
Glutathione S-transferase in chemotherapy resistance and in carcinogenesis
Published in Biochemistry and cell biology (01-05-1992)“…Cytosolic glutathione S-transferases are composed of two monomeric subunits. These monomers are the products of different gene families designated alpha, mu,…”
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12
Language as Cultural Practice: Mexicanos en el Norte
Published in Journal of Language and Social Psychology (01-09-2003)“…"Language as Cultural Practice: Mexicanos en el Norte" by Sandra R. Schecter and Robert Bayley is reviewed…”
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