Search Results - "SCHAUB, J"

Deep learning predicts function of live retinal pigment epithelium from quantitative microscopy by Schaub, Nicholas J, Hotaling, Nathan A, Manescu, Petre, Padi, Sarala, Wan, Qin, Sharma, Ruchi, George, Aman, Chalfoun, Joe, Simon, Mylene, Ouladi, Mohamed, Simon, Jr, Carl G, Bajcsy, Peter, Bharti, Kapil

“…Increases in the number of cell therapies in the preclinical and clinical phases have prompted the need for reliable and noninvasive assays to validate…”
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Unbiased image segmentation assessment toolkit for quantitative differentiation of state-of-the-art algorithms and pipelines by Goyal, Vishakha, Schaub, Nick J, Voss, Ty C, Hotaling, Nathan A

“…Image segmentation pipelines are commonly used in microscopy to identify cellular compartments like nucleus and cytoplasm, but there are few standards for…”
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Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells by Fiskus, Warren, Sharma, Sunil, Qi, Jun, Valenta, John A, Schaub, Leasha J, Shah, Bhavin, Peth, Karissa, Portier, Bryce P, Rodriguez, Melissa, Devaraj, Santhana G T, Zhan, Ming, Sheng, Jianting, Iyer, Swaminathan P, Bradner, James E, Bhalla, Kapil N

“…The bromodomain and extra-terminal (BET) protein family members, including BRD4, bind to acetylated lysines on histones and regulate the expression of…”
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Assessing Efficiency in Artificial Neural Networks by Schaub, Nicholas J., Hotaling, Nathan

“…The purpose of this work was to develop an assessment technique and subsequent metrics that help in developing an understanding of the balance between network…”
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First Leptophobic Dark Matter Search from the Coherent–CAPTAIN-Mills Liquid Argon Detector by Aguilar-Arevalo, A. A., Alves, D. S. M., Biedron, S., Boissevain, J., Borrego, M., Chavez-Estrada, M., Chavez, A., Conrad, J. M., Cooper, R. L., Diaz, A., Distel, J. R., D’Olivo, J. C., Dunton, E., Dutta, B., Elliott, A., Evans, D., Fields, D., Greenwood, J., Gold, M., Gordon, J., Guarincerri, E., Huang, E. C., Kamp, N., Kelsey, C., Knickerbocker, K., Lake, R., Louis, W. C., Mahapatra, R., Maludze, S., Mirabal, J., Moreno, R., Neog, H., deNiverville, P., Pandey, V., Plata-Salas, J., Poulson, D., Ray, H., Renner, E., Schaub, T. J., Shaevitz, M. H., Smith, D., Sondheim, W., Szelc, A. M., Taylor, C., Thompson, W. H., Thornton, R. T., Tripathi, M., Van Berg, R., Van de Water, R. G., Verma, S., Walker, K.

“…We report the first results of a search for leptophobic dark matter (DM) from the Coherent–CAPTAIN-Mills (CCM) liquid argon (LAr) detector. An engineering run…”
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Molecular basis for interactions between an acyl carrier protein and a ketosynthase by Milligan, Jacob C., Lee, D. John, Jackson, David R., Schaub, Andrew J., Beld, Joris, Barajas, Jesus F., Hale, Joseph J., Luo, Ray, Burkart, Michael D., Tsai, Shiou-Chuan

“…Fatty acid synthases are dynamic ensembles of enzymes that can biosynthesize long hydrocarbon chains efficiently. Here we visualize the interaction between the…”
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Quantitative, traceable determination of cell viability using absorbance microscopy by Babakhanova, Greta, Zimmerman, Stephen M, Pierce, Laura T, Sarkar, Sumona, Schaub, Nicholas J, Simon, Jr, Carl G

“…Cell viability, an essential measurement for cell therapy products, lacks traceability. One of the most common cell viability tests is trypan blue dye…”
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Using unmanned aerial vehicles (UAVs) to measure jellyfish aggregations by Schaub, Jessica, Hunt, Brian P. V., Pakhomov, Evgeny A., Holmes, Keith, Lu, Yuhao, Quayle, Lucy

“…Unmanned aerial vehicles (UAVs, or drones) are becoming increasingly common as tools to perform high-resolution but broad-scale measurements of habitats and…”
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Strange quark contributions to parity-violating asymmetries in the backward angle G0 electron scattering experiment by Androić, D, Armstrong, D S, Arvieux, J, Bailey, S L, Beck, D H, Beise, E J, Benesch, J, Benmokhtar, F, Bimbot, L, Birchall, J, Bosted, P, Breuer, H, Capuano, C L, Chao, Y-C, Coppens, A, Davis, C A, Ellis, C, Flores, G, Franklin, G, Furget, C, Gaskell, D, Gericke, M T W, Grames, J, Guillard, G, Hansknecht, J, Horn, T, Jones, M, King, P M, Korsch, W, Kox, S, Lee, L, Liu, J, Lung, A, Mammei, J, Martin, J W, McKeown, R D, Mihovilovic, M, Micherdzinska, A, Mkrtchyan, H, Muether, M, Page, S A, Papavassiliou, V, Pate, S F, Phillips, S K, Pillot, P, Pitt, M L, Poelker, M, Quinn, B, Ramsay, W D, Real, J-S, Roche, J, Roos, P, Schaub, J, Seva, T, Simicevic, N, Smith, G R, Spayde, D T, Stutzman, M, Suleiman, R, Tadevosyan, V, van Oers, W T H, Versteegen, M, Voutier, E, Vulcan, W, Wells, S P, Williamson, S E, Wood, S A

“…We have measured parity-violating asymmetries in elastic electron-proton and quasielastic electron-deuteron scattering at Q2=0.22 and 0.63 GeV2. They are…”
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The Effect of Surface Modification of Aligned Poly-L-Lactic Acid Electrospun Fibers on Fiber Degradation and Neurite Extension by Schaub, Nicholas J, Le Beux, Clémentine, Miao, Jianjun, Linhardt, Robert J, Alauzun, Johan G, Laurencin, Danielle, Gilbert, Ryan J

“…The surface of aligned, electrospun poly-L-lactic acid (PLLA) fibers was chemically modified to determine if surface chemistry and hydrophilicity could improve…”
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Quality of Caregiver-child Interactions in Early Child Care Centers in Bangladesh: Measurement and Training by Helmerhorst, K. O. W., Dutta, M., Khanom, F., Zaman, S. S., Gevers Deynoot-Schaub, M. J. J. M.

“…The current study assessed (1) the importance of six caregiver interactions skills (sensitive responsiveness, respect for autonomy, structuring and limit…”
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Designing Trojan Detectors in Neural Networks Using Interactive Simulations by Bajcsy, Peter, Schaub, Nicholas J., Majurski, Michael

“…This paper addresses the problem of designing trojan detectors in neural networks (NNs) using interactive simulations. Trojans in NNs are defined as triggers…”
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Electrospun fibers： a guiding scaffold for research and regeneration of the spinal cord by Schaub, Nicholas

“…The challenge to regenerating the nervous system compared to other tissues in the body is the complexity of the tissue. For example, a small amount of scar…”
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Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain by Kwon, Young D, Pegu, Amarendra, Yang, Eun Sung, Zhang, Baoshan, Bender, Michael F, Asokan, Mangaiarkarasi, Liu, Qingbo, McKee, Krisha, Lin, Bob C, Liu, Tracy, Louder, Mark K, Rawi, Reda, Reveiz, Mateo, Schaub, Andrew J, Shen, Chen-Hsiang, Doria-Rose, Nicole A, Lusso, Paolo, Mascola, John R, Kwong, Peter D

“…The amino-acid composition of the immunoglobulin variable region has been observed to impact antibody pharmacokinetics (PK). Here, we sought to improve the PK…”
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Effects of the Caregiver Interaction Profile Training on Caregiver–Child Interactions in Dutch Child Care Centers: A Randomized Controlled Trial by Helmerhorst, Katrien O. W., Riksen-Walraven, J. Marianne A., Fukkink, Ruben G., Tavecchio, Louis W. C., Gevers Deynoot-Schaub, Mirjam J. J. M.

“…Background Previous studies underscore the need to improve caregiver–child interactions in early child care centers. Objective In this study we used a…”
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Modeling, validation and verification of three-dimensional cell-scaffold contacts from terabyte-sized images by Bajcsy, Peter, Yoon, Soweon, Florczyk, Stephen J, Hotaling, Nathan A, Simon, Mylene, Szczypinski, Piotr M, Schaub, Nicholas J, Simon, Jr, Carl G, Brady, Mary, Sriram, Ram D

“…Cell-scaffold contact measurements are derived from pairs of co-registered volumetric fluorescent confocal laser scanning microscopy (CLSM) images (z-stacks)…”
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Germanium-on-SOI Infrared Detectors for Integrated Photonic Applications by Koester, S.J., Schaub, J.D., Dehlinger, G., Chu, J.O.

“…An overview of recent results on high-speed germanium-on-silicon-on-insulator (Ge-on-SOI) photodetectors and their prospects for integrated optical…”
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Rapid Detection of Neutrophil Oxidative Burst Capacity is Predictive of Whole Blood Cytokine Responses by Vernon, Philip J, Schaub, Leasha J, Dallelucca, Jurandir J, Pusateri, Anthony E, Sheppard, Forest R

“…Maladaptive immune responses, particularly cytokine and chemokine-driven, are a significant contributor to the deleterious inflammation present in many types…”
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Controlled release of 6-aminonicotinamide from aligned, electrospun fibers alters astrocyte metabolism and dorsal root ganglia neurite outgrowth by Schaub, Nicholas J, Gilbert, Ryan J

“…Following central nervous system (CNS) injury, activated astrocytes form a glial scar that inhibits the migration of axons ultimately leading to regeneration…”
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Modeling Linear and Cyclic PKS Intermediates through Atom Replacement by Shakya, Gaurav, Rivera, Heriberto, Lee, D. John, Jaremko, Matt J, La Clair, James J, Fox, Daniel T, Haushalter, Robert W, Schaub, Andrew J, Bruegger, Joel, Barajas, Jesus F, White, Alexander R, Kaur, Parminder, Gwozdziowski, Emily R, Wong, Fiona, Tsai, Shiou-Chuan, Burkart, Michael D

“…The mechanistic details of many polyketide synthases (PKSs) remain elusive due to the instability of transient intermediates that are not accessible via…”
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