Search Results - "SCHAPER, W"

Collateral vessels reduce mortality by Schaper, W

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Arteriogenesis versus angiogenesis: similarities and differences by Heil, M., Eitenmüller, Inka, Schmitz‐Rixen, T., Schaper, W.

“…Cardiovascular diseases account for more than half of total mortality before the age of 75 in industrialized countries. To develop therapies promoting the…”
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The temporal and spatial distribution of macrophage subpopulations during arteriogenesis by Troidl, C, Jung, G, Troidl, K, Hoffmann, J, Mollmann, H, Nef, H, Schaper, W, Hamm, C W, Schmitz-Rixen, T

“…Chronic arterial occlusion leads to growth of collaterals - a process termed arteriogenesis, in which macrophages play a prominent role in remodelling and…”
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Cerebral Arteriogenesis is Enhanced by Pharmacological as Well as Fluid-Shear-Stress Activation of the Trpv4 Calcium Channel by Schierling, W, Troidl, K, Apfelbeck, H, Troidl, C, Kasprzak, P.M, Schaper, W, Schmitz-Rixen, T

“…Abstract Objectives This study aimed to determine the importance of the shear-stress-sensitive calcium channels Trpc1, Trpm7, Trpp2, Trpv2 (transient receptor…”
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Hypoxia-Induced Hyperpermeability in Brain Microvessel Endothelial Cells Involves VEGF-Mediated Changes in the Expression of Zonula Occludens-1 by Fischer, S., Wobben, M., Marti, H.H., Renz, D., Schaper, W.

“…In vivo, hypoxia is known to damage the blood–brain barrier (BBB) leading to the development of vasogenic brain edema. Primary cultures of porcine brain…”
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Arteriogenesis Versus Angiogenesis: Two Mechanisms of Vessel Growth by Buschmann, I, Schaper, W

“…I. Buschmann and W. Schaper I. Buschmann and W. Schaper are in the Department for Experimental Cardiology of the Max Planck Institute for Physiological and…”
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Monocyte activation in angiogenesis and collateral growth in the rabbit hindlimb by Arras, M, Ito, W D, Scholz, D, Winkler, B, Schaper, J, Schaper, W

“…We have previously shown that monocytes adhere to the vascular wall during collateral vessel growth (arteriogenesis) and capillary sprouting (angiogenesis). In…”
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Local Monocyte Chemoattractant Protein-1 Therapy Increases Collateral Artery Formation in Apolipoprotein E–Deficient Mice but Induces Systemic Monocytic CD11b Expression, Neointimal Formation, and Plaque Progression by van Royen, N, Hoefer, I, Böttinger, M, Hua, J, Grundmann, S, Voskuil, M, Bode, C, Schaper, W, Buschmann, I, Piek, J J

“…ABSTRACT—Monocyte chemoattractant protein-1 (MCP-1) stimulates the formation of a collateral circulation on arterial occlusion. The present study served to…”
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Deep Brain Stimulation in Epilepsy: A Role for Modulation of the Mammillothalamic Tract in Seizure Control? by Schaper, Frédéric L W V J, Plantinga, Birgit R, Colon, Albert J, Wagner, G Louis, Boon, Paul, Blom, Nadia, Gommer, Erik D, Hoogland, Govert, Ackermans, Linda, Rouhl, Rob P W, Temel, Yasin

“…Abstract BACKGROUND Deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) can improve seizure control for patients with drug-resistant…”
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Ultrastructure and molecular histology of rabbit hind-limb collateral artery growth (arteriogenesis) by SCHOLZ, D, ITO, W, FLEMING, I, DEINDL, E, SAUER, A, WIESNET, M, BUSSE, R, SCHAPER, J, SCHAPER, W

“…Previous studies in the canine heart had shown that the growth of collateral arteries occurs via proliferative enlargement of pre-existing arteriolar…”
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Brain lesion locations associated with secondary seizure generalization in tumors and strokes by Nordberg, Janne, Schaper, Frederic L. W. V. J., Bucci, Marco, Nummenmaa, Lauri, Joutsa, Juho

“…Structural brain lesions are the most common cause of adult‐onset epilepsy. The lesion location may contribute to the risk for epileptogenesis, but whether…”
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Calcium-dependent signalling is essential during collateral growth in the pig hind limb-ischemia model by Troidl, C, Nef, H, Voss, S, Schilp, A, Kostin, S, Troidl, K, Szardien, S, Rolf, A, Schmitz-Rixen, T, Schaper, W, Hamm, C.W, Elsässer, A, Möllmann, H

“…Abstract We investigated the effect of pharmacological activation of the Ca2+ -channel transient receptor potential cation channel, subfamily V, member 4…”
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Mapping Lesion-Related Epilepsy to a Human Brain Network by Schaper, Frederic L W V J, Nordberg, Janne, Cohen, Alexander L, Lin, Christopher, Hsu, Joey, Horn, Andreas, Ferguson, Michael A, Siddiqi, Shan H, Drew, William, Soussand, Louis, Winkler, Anderson M, Simó, Marta, Bruna, Jordi, Rheims, Sylvain, Guenot, Marc, Bucci, Marco, Nummenmaa, Lauri, Staals, Julie, Colon, Albert J, Ackermans, Linda, Bubrick, Ellen J, Peters, Jurriaan M, Wu, Ona, Rost, Natalia S, Grafman, Jordan, Blumenfeld, Hal, Temel, Yasin, Rouhl, Rob P W, Joutsa, Juho, Fox, Michael D

“…It remains unclear why lesions in some locations cause epilepsy while others do not. Identifying the brain regions or networks associated with epilepsy by…”
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Deep brain stimulation of the anterior nucleus of the thalamus for drug-resistant epilepsy by Bouwens van der Vlis, Tim A. M., Schijns, Olaf E. M. G., Schaper, Frédéric L. W. V. J., Hoogland, Govert, Kubben, Pieter, Wagner, Louis, Rouhl, Rob, Temel, Yasin, Ackermans, Linda

“…Despite the use of first-choice anti-epileptic drugs and satisfactory seizure outcome rates after resective epilepsy surgery, a considerable percentage of…”
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Brain stimulation and brain lesions converge on common causal circuits in neuropsychiatric disease by Siddiqi, Shan H., Schaper, Frederic L. W. V. J., Horn, Andreas, Hsu, Joey, Padmanabhan, Jaya L., Brodtmann, Amy, Cash, Robin F. H., Corbetta, Maurizio, Choi, Ki Sueng, Dougherty, Darin D., Egorova, Natalia, Fitzgerald, Paul B., George, Mark S., Gozzi, Sophia A., Irmen, Frederike, Kuhn, Andrea A., Johnson, Kevin A., Naidech, Andrew M., Pascual-Leone, Alvaro, Phan, Thanh G., Rouhl, Rob P. W., Taylor, Stephan F., Voss, Joel L., Zalesky, Andrew, Grafman, Jordan H., Mayberg, Helen S., Fox, Michael D.

“…Damage to specific brain circuits can cause specific neuropsychiatric symptoms. Therapeutic stimulation to these same circuits may modulate these symptoms. To…”
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Initial case series of a novel sensing deep brain stimulation device in drug-resistant epilepsy and consistent identification of alpha/beta oscillatory activity: A feasibility study by Chua, Melissa M J, Vissani, Matteo, Liu, David D, Schaper, Frederic L W V J, Warren, Aaron E L, Caston, Rose, Dworetzky, Barbara A, Bubrick, Ellen J, Sarkis, Rani A, Cosgrove, G Rees, Rolston, John D

“…Here, we report a retrospective, single-center experience with a novel deep brain stimulation (DBS) device capable of chronic local field potential (LFP)…”
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Effects of local MCP-1 protein therapy on the development of the collateral circulation and atherosclerosis in Watanabe hyperlipidemic rabbits by VAN ROYEN, N, HOEFER, I, BUSCHMANN, I, KOSTIN, S, VOSKUIL, M, BODE, Ch, SCHAPER, W, PIEK, J. J

“…The objective of our study was to quantify the arteriogenic potency of Monocyte Chemoattractant Protein-1 (MCP-1) under hyperlipidemic conditions…”
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Exercise Linked to Transient Increase in Expression and Activity of Cation Channels in Newly Formed Hind-limb Collaterals by Sayed, A, Schierling, W, Troidl, K, Rüding, I, Nelson, K, Apfelbeck, H, Benli, I, Schaper, W, Schmitz-Rixen, T

“…Abstract Objective This study aimed to compare arteriogenesis after femoral artery occlusion as influenced by exercise or arteriovenous shunt and follow…”
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A transdiagnostic network for psychiatric illness derived from atrophy and lesions by Taylor, Joseph J., Lin, Christopher, Talmasov, Daniel, Ferguson, Michael A., Schaper, Frederic L. W. V. J., Jiang, Jing, Goodkind, Madeleine, Grafman, Jordan, Etkin, Amit, Siddiqi, Shan H., Fox, Michael D.

“…Psychiatric disorders share neurobiology and frequently co-occur. This neurobiological and clinical overlap highlights opportunities for transdiagnostic…”
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Angiogenesis but not collateral growth is associated with ischemia after femoral artery occlusion by Ito, W D, Arras, M, Scholz, D, Winkler, B, Htun, P, Schaper, W

“…It remains unclear whether capillary sprouting (angiogenesis) and in situ growth of muscular collateral arteries share the same or different molecular…”
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