Search Results - "SCHAFFER, L. W"

Arrhythmias in the setting of hematopoietic cell transplants by Tonorezos, E S, Stillwell, E E, Calloway, J J, Glew, T, Wessler, J D, Rebolledo, B J, Pham, A, Steingart, R M, Lazarus, H, Gale, R P, Jakubowski, A A, Schaffer, W L

“…Prior studies report that 9–27% of persons receiving a hematopoietic cell transplant develop arrhythmias, but the effect on outcomes is largely unknown. We…”
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Antithrombotic efficacy of recombinant tick anticoagulant peptide : a potent inhibitor of coagulation factor Xa in a primate model of arterial thrombosis by SCHAFFER, L. W, DAVIDSON, J. T, VLASUK, G. P, SIEGL, P. K. S

“…Tick anticoagulant peptide is a specific, potent inhibitor of blood coagulation factor Xa. The effects of recombinant tick anticoagulant peptide (rTAP) and…”
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Characterization of recombinant tick anticoagulant peptide. A highly selective inhibitor of blood coagulation factor Xa by Neeper, M P, Waxman, L, Smith, D E, Schulman, C A, Sardana, M, Ellis, R W, Schaffer, L W, Siegl, P K, Vlasuk, G P

“…Tick anticoagulant peptide (TAP) is a potent, highly selective inhibitor of blood coagulation factor Xa (Waxman, L., Smith, D. E., Arcuri, K. E., and Vlasuk,…”
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The cholecystokinin receptor antagonist devazepide enhances morphine-induced analgesia but not morphine-induced respiratory depression in the squirrel monkey by Dourish, C T, O'Neill, M F, Schaffer, L W, Siegl, P K, Iversen, S D

“…The effects of the cholecystokinin antagonist devazepide on analgesia and respiratory depression induced by morphine in squirrel monkeys were examined. Pain…”
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Selective factor Xa inhibition by recombinant antistasin prevents vascular graft thrombosis in baboons by SCHAFFER, L. W, DAVIDSON, J. T, VLASUK, G. P, DUNWIDDIE, C. T, SIEGL, P. K. S

“…A baboon model of high-shear, platelet-dependent vascular graft thrombosis was used to assess the antithrombotic effect of recombinant antistasin (rATS), a…”
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Anticoagulant efficacy and immunogenicity of the selective factor Xa inhibitor antistasin following subcutaneous administration in the rhesus monkey by Dunwiddie, C T, Nutt, E M, Vlasuk, G P, Siegl, P K, Schaffer, L W

“…The antithrombotic efficacy and duration of action of a single subcutaneous administration of the selective factor Xa inhibitor recombinant antistasin (rATS)…”
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Immunocytochemical localization of platelets in baboon hepatic sinusoids using monoclonal mouse anti-human platelet glycoprotein IIIa following induction of thrombocytopenia by Frank, J D, Gould, R J, Schaffer, L W, Davidson, J T, Gibson, R E, Patrick, D H, Vonderfecht, S L, Cartwright, M E

“…A commercially available mouse monoclonal antibody to human platelet glycoprotein IIIa was used to demonstrate sequestration of platelets in hepatic biopsies…”
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Acute hypotensive responses to peptide inhibitors of renin in conscious monkeys: an effect on blood pressure independent of plasma renin inhibition by Schaffer, L W, Schorn, T W, Winquist, R J, Strouse, J F, Payne, L, Chakravarty, P K, de Laszlo, S E, tenBroeke, J, Veber, D F, Greenlee, W J

“…In order to investigate the hypotensive mechanisms of action of peptide renin inhibitors, blood pressure responses to five renin inhibitors were compared with…”
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In vivo pharmacology of L-159,913, a new highly potent and selective nonpeptide angiotensin II receptor antagonist by Gabel, R A, Kivlighn, S D, Zingaro, G J, Schorn, T W, Schaffer, L W, Ashton, W T, Chang, L L, Flanagan, K, Greenlee, W J, Siegl, P K

“…The present study was designed to characterize the in vivo pharmacology of L-159,913 (4-[[2'-(N-benzoylsulfamoyl)biphenyl-4-yl]-5butyl-2,4-dihydr o-2-…”
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In vivo pharmacology of a novel AT1 selective angiotensin II receptor antagonist, MK-996 by Kivlighn, S D, Zingaro, G J, Gabel, R A, Broten, T P, Schorn, T W, Schaffer, L W, Naylor, E M, Chakravarty, P K, Patchett, A A, Greenlee, W J

“…MK-996, N-(4'-(5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl- methyl)1,1'-biphenyl-2-yl)-sulfonylbenzamide, is a potent, orally active, highly selective,…”
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Recombinant leech antiplatelet protein prevents collagen-mediated platelet aggregation but not collagen graft thrombosis in baboons by SCHAFFER, L. W, DAVIDSON, J. T, SIEGL, P. K. S, GOULD, R. J, NUTT, R. F, BRADY, S. F, CONNOLLY, T. M

“…Leech antiplatelet protein (LAPP) is a specific inhibitor of collagen-induced human platelet aggregation and adhesion to collagen under static conditions…”
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A highly potent, orally active imidazo-[4,5-b]pyridine biphenylacylsulfonamide (MK-996;L-159,282) : a new AT1-selective angiotensin II receptor antagonist by CHAKRAVARTY, P. K, NAYLOR, E. M, SCHORN, T. W, SCHAFFER, L. W, BROTEN, T. P, SIEGL, P. K. S, PATCHETT, A. A, GREENLEE, W. J, CHEN, A, CHANG, R. S. L, TSING-BAU CHEN, FAUST, K. A, LOTTI, V. J, KIVLIGHN, S. D, GABLE, R. A, ZINGARO, G. J

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Prevalence and correlates of rheumatic heart disease in American Indians (The Strong Heart Study) by Schaffer, Wendy L., Galloway, James M., Roman, Mary J., Palmieri, Vittorio, Liu, Jennifer E., Lee, Elisa T., Best, Lyle G., Fabsitz, Richard R., Howard, Barbara V., Devereux, Richard B.

“…Rheumatic mitral stenosis affects approximately 1 in 200 middle-aged to elderly American Indians in a population-based sample and is associated with lower…”
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Non-peptide fibrinogen receptor antagonists. VII: Design and synthesis of a potent, orally active fibrinogen receptor antagonist by DUGGAN, M. E, NAYLOR-OLSEN, A. M, LYNCH, R. J, MANNO, P. D, SCHAFFER, L. W, SMITH, R. L, PERKINS, J. J, ANDERSON, P. S, CHANG, C. T.-C, COOK, J. J, GOULD, R. J, IHLE, N. C, HARTMAN, G. D, LYNCH, J. J

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