Search Results - "SCHAFFER, F"

Monoclonal antibodies: the new magic bullets for allergy: IUPHAR Review 17 by Landolina, N, Levi‐Schaffer, F

“…Allergic diseases and conditions are widespread and their incidence is on the increase. They are characterized by the activation of mast cells resident in…”
Get full text

sCD48 is anti‐inflammatory in Staphylococcus aureus Enterotoxin B‐induced eosinophilic inflammation by Gangwar, R. S., Levi‐Schaffer, F.

“…Background Staphylococcus aureus, one of the most important pathogens, is heavily associated with allergy. S. aureus and its toxins interact with eosinophils…”
Get full text

AllergoOncology – the impact of allergy in oncology: EAACI position paper by Jensen‐Jarolim, E., Bax, H. J., Bianchini, R., Capron, M., Corrigan, C., Castells, M., Dombrowicz, D., Daniels‐Wells, T. R., Fazekas, J., Fiebiger, E., Gatault, S., Gould, H. J., Janda, J., Josephs, D. H., Karagiannis, P., Levi‐Schaffer, F., Meshcheryakova, A., Mechtcheriakova, D., Mekori, Y., Mungenast, F., Nigro, E. A., Penichet, M. L., Redegeld, F., Saul, L., Singer, J., Spicer, J. F., Siccardi, A. G., Spillner, E., Turner, M. C., Untersmayr, E., Vangelista, L., Karagiannis, S. N.

“…Th2 immunity and allergic immune surveillance play critical roles in host responses to pathogens, parasites and allergens. Numerous studies have reported…”
Get full text

Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the Task Force for Immunopharmacology by Roth‐Walter, F., Adcock, I. M., Benito‐Villalvilla, C., Bianchini, R., Bjermer, L., Caramori, G., Cari, L., Chung, K. F., Diamant, Z., Eguiluz‐Gracia, I., Knol, E. F., Jesenak, M., Levi‐Schaffer, F., Nocentini, G., O'Mahony, L., Palomares, O., Redegeld, F., Sokolowska, M., Van Esch, B. C. A. M., Stellato, C.

“…The accumulation of senescent cells drives inflammaging and increases morbidity of chronic inflammatory lung diseases. Immune responses are built upon dynamic…”
Get full text

Modulation of allergic responses by mitochondrial STAT3 inhibitors by Erlich, T. H., Sharkia, I., Landolina, N., Assayag, M., Goldberger, O., Berkman, N., Levi‐Schaffer, F., Razin, E.

“…Background Recently, we have shown that mast cell mitochondrial STAT3 could serve as a new target for the regulation of the allergic response as it plays an…”
Get full text

Eosinophils: ‘new’ roles for ‘old’ cells by Munitz, A., Levi‐Schaffer, F.

“…Prominent blood and tissue eosinophilia is manifested in a number of inflammatory states, particularly in allergic diseases. Eosinophils are a source of…”
Get full text

Interacting mast cells and eosinophils acquire an enhanced activation state in vitro by Elishmereni, M., Bachelet, I., Nissim Ben‐Efraim, A. H., Mankuta, D., Levi‐Schaffer, F.

“…Background Mast cells (MCs) and eosinophils (Eos), the key effector cells in allergy, are abundantly co‐localized particularly in the late and chronic stages…”
Get full text

Lipoxin B4 promotes the resolution of allergic inflammation in the upper and lower airways of mice by Karra, L, Haworth, O, Priluck, R, Levy, B D, Levi-Schaffer, F

“…Chronic mucosal inflammation is the hallmark of important and common airway diseases, such as allergic rhinitis (AR) and asthma. Lipoxin A 4 (LXA 4 ) is an…”
Get full text

Physical interactions between mast cells and eosinophils: a novel mechanism enhancing eosinophil survival in vitro by Elishmereni, M, Alenius, H.T, Bradding, P, Mizrahi, S, Shikotra, A, Minai-Fleminger, Y, Mankuta, D, Eliashar, R, Zabucchi, G, Levi-Schaffer, F

“…To cite this article: Elishmereni M, Alenius HT, Bradding P, Mizrahi S, Shikotra A, Minai-Fleminger Y, Mankuta D, Eliashar R, Zabucchi G, Levi-Schaffer F…”
Get full text

AllergoOncology: Opposite outcomes of immune tolerance in allergy and cancer by Jensen‐Jarolim, E., Bax, H. J., Bianchini, R., Crescioli, S., Daniels‐Wells, T. R., Dombrowicz, D., Fiebiger, E., Gould, H. J., Irshad, S., Janda, J., Josephs, D. H., Levi‐Schaffer, F., O′Mahony, L., Pellizzari, G., Penichet, M. L., Redegeld, F., Roth‐Walter, F., Singer, J., Untersmayr, E., Vangelista, L., Karagiannis, S. N.

“…While desired for the cure of allergy, regulatory immune cell subsets and nonclassical Th2‐biased inflammatory mediators in the tumour microenvironment can…”
Get full text

CD48 on blood leukocytes and in serum of asthma patients varies with severity by Gangwar, R. S., Minai‐Fleminger, Y., Seaf, M., Gutgold, A., Shikotra, A., Barber, C., Chauhan, A., Holgate, S., Bradding, P., Howarth, P., Eliashar, R., Berkman, N., Levi‐Schaffer, F.

“…Background CD48 is a membrane receptor (mCD48) on eosinophils and mast cells and exists in a soluble form (sCD48). CD48 has a pivotal role in murine asthma and…”
Get full text

The CD48 receptor mediates Staphylococcus aureus human and murine eosinophil activation by Minai-Fleminger, Y., Gangwar, R. S., Migalovich-Sheikhet, H., Seaf, M., Leibovici, V., Hollander, N., Feld, M., Moses, A. E., Homey, B., Levi-Schaffer, F.

“…Summary Background Allergy is characterized by eosinophilia and an increased susceptibility to microbial infection. Atopic dermatitis (AD) is typically…”
Get full text

Ultrafast imprinting of topologically protected magnetic textures via pulsed electrons by Schäffer, A. F., Dürr, H. A., Berakdar, J.

“…Short electron pulses are demonstrated to trigger and control magnetic excitations, even at low electron current densities. We show that the tangential…”
Get full text

Angiogenesis in asthma by Ribatti, D., Puxeddu, I., Crivellato, E., Nico, B., Vacca, A., Levi-Schaffer, F.

“…Summary Asthma is a chronic inflammatory disease of the airways characterized by infiltration and activation of inflammatory cells and by structural changes,…”
Get full text

Role of reactive oxygen species (ROS) in apoptosis induction by Simon, H U, Haj-Yehia, A, Levi-Schaffer, F

“…Reactive oxygen species (ROS) and mitochondria play an important role in apoptosis induction under both physiologic and pathologic conditions. Interestingly,…”
Get full text

Osteopontin is expressed and functional in human eosinophils by Puxeddu, I., Berkman, N., Ribatti, D., Bader, R., Haitchi, H. M., Davies, D. E., Howarth, P. H., Levi‐Schaffer, F.

“…To cite this article: Puxeddu I, Berkman N, Ribatti D, Bader R, Haitchi HM, Davies DE, Howarth PH, Levi‐Schaffer F. Osteopontin is expressed and functional in…”
Get full text

Eosinophil major basic protein activates human cord blood mast cells primed with fibroblast membranes by integrin‐β1 by Ben‐Zimra, M., Bachelet, I., Seaf, M., Gleich, G. J., Levi‐Schaffer, F.

“…Background Mast cell (MC) – eosinophil (Eos) activating cross‐talk might be critical for the severity and chronicity of allergy. Among soluble mediators,…”
Get full text

AllergoOncology: ultra‐low IgE, a potential novel biomarker in cancer—a Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI) by Ferastraoaru, D., Bax, H. J., Bergmann, C., Capron, M., Castells, M., Dombrowicz, D., Fiebiger, E., Gould, H. J., Hartmann, K., Jappe, U., Jordakieva, G., Josephs, D. H., Levi‐Schaffer, F., Mahler, V., Poli, A., Rosenstreich, D., Roth‐Walter, F., Shamji, M., Steveling‐Klein, E. H., Turner, M. C., Untersmayr, E., Karagiannis, S. N., Jensen‐Jarolim, E.

“…Elevated serum IgE levels are associated with allergic disorders, parasitosis and specific immunologic abnormalities. In addition, epidemiological and…”
Get full text

In Memory and Celebration: Dr. James J. Lee by Rosenberg, H. F., Fryer, A. D., Munitz, A., Bochner, B. S., Jacoby, D. B., Levi‐Schaffer, F., Gleich, G. J., Furuta, G. T., Rothenberg, M. E., Lacy, P., Fulkerson, P. C., Hogan, S. P., Ackerman, S. J., Foster, P. S.

Get full text

The search for mast cell and basophil models – are we getting closer to pathophysiological relevance? by Siebenhaar, F., Falcone, F. H., Tiligada, E., Hammel, I., Maurer, M., Sagi‐Eisenberg, R., Levi‐Schaffer, F.

Get full text