Search Results - "SCHAEFER, Jonathan B"

Genetic Effects on Age-Dependent Onset and Islet Cell Autoantibody Markers in Type 1 Diabetes by GRAHAM, Jinko, HAGOPIAN, William A, PALMER, Jerry P, JANER-VILLANUEVA, Marta, HOOD, Leroy, SUNDKVIST, Göran, LERNMARK, Ake, BRESLOW, Norman, DAHLQUIST, Gisela, BLOHME, Göran, KOCKUM, Ingrid, LOU SHENG LI, SANJEEVI, Carani B, LOWE, Robert M, SCHAEFER, Jonathan B, ZARGHAMI, Marjan, DAY, Heather L, LANDIN-OLSSON, Mona

“…Genetic Effects on Age-Dependent Onset and Islet Cell Autoantibody Markers in Type 1 Diabetes Jinko Graham 1 , William A. Hagopian 2 , Ingrid Kockum 3 , Lou…”
Get full text

T Cell Activation Up-Regulates Cyclic Nucleotide Phosphodiesterases 8A1 and 7A3 by Glavas, Natalie A., Ostenson, Cari, Schaefer, Jonathan B., Vasta, Valeria, Beavo, Joseph A.

“…Agents that increase intracellular cAMP inhibit the activation and function of T cells and can lead to cell death. Recently, it has been postulated that cAMP…”
Get full text

Protein-linked Ubiquitin Chain Structure Restricts Activity of Deubiquitinating Enzymes by Schaefer, Jonathan B., Morgan, David O.

“…The attachment of lysine 48 (Lys48)-linked polyubiquitin chains to proteins is a universal signal for degradation by the proteasome. Here, we report that long…”
Get full text

Cloning and Characterization of a cAMP-Specific Phosphodiesterase (TbPDE2B) from Trypanosoma brucei by Rascón, Ana, Soderling, Scott H., Schaefer, Jonathan B., Beavo, Joseph A.

“…Here we report the cloning, expression, and characterization of a cAMP-specific phosphodiesterase (PDE) from Trypanosoma brucei (TbPDE2B). Using a…”
Get full text

RB from a Bud's Eye View by Schaefer, Jonathan B, Breeden, Linda L

“…RB and related proteins block transcriptional activation of genes critical to initiation of the cell cycle and suppress unwanted cell division. The circuitry…”
Get full text

Development of type 1 diabetes in wild bank voles associated with islet autoantibodies and the novel ljungan virus by Niklasson, Bo, Heller, Knud E, Schønecker, Bryan, Bildsøe, Mogens, Daniels, Terri, Hampe, Christiane S, Widlund, Per, Simonson, William T, Schaefer, Jonathan B, Rutledge, Elizabeth, Bekris, Lynn, Lindberg, A Michael, Johansson, Susanne, Ortqvist, Eva, Persson, Bengt, Lernmark, Ake

“…Wild bank voles (Clethrionomys glareolus) may develop diabetes in laboratory captivity. The aim of this study was to test whether bank voles develop type 1…”
Get more information

The length of the CTLA-4 microsatellite (AT)(N)-repeat affects the risk for type 1 diabetes by Lowe, Michael R., Graham, J, Sund, G., Kockum, I, Landin-Olsson, M., Schaefer, Jonathan B, Torn, C., Lernmark, A., Dahlquist, G, Blohme, G

“…CTLA-4 is important to down-regulating T cell responses and has been implicated in type 1 (insulin dependent) diabetes mellitus in both linkage and association…”
Get full text

The Length of the CTLA-4 Microsatellite (AT)N-Repeat Affects the Risk for Type 1 Diabetes: For the Swedish Childhood Diabetes Study Group by Lowe, Robert M., Graham, Jinko, Sund, Greg, Kockum, Ingrid, Landin-Olsson, Mona, Schaefer, Jonathan b., Törn, Carina, Lernmark, Ake, Dahlquist, Gisela, Blohmé, GÖRan

“…CTLA-4 is important to down-regulating T cell responses and has been implicated in type 1 (insulin dependent) diabetes mellitus in both linkage and association…”
Get full text

The length of the CTLA-4 microsatellite (AT)N-Repeat affects the risk for type 1 diabetes by LOWE, Robert M, GRAHAM, Jinko, SUND, Greg, KOCKUM, Ingrid, LANDIN-OLSSON, Mona, SCHAEFER, Jonathan B, TÖRN, Carina, LERNMARK, Ake, DAHLQUIST, Gisela

Get full text