Search Results - "SCHÜLLER, Stephanie"
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Experimental models to study intestinal microbes-mucus interactions in health and disease
Published in FEMS microbiology reviews (01-09-2019)“…A close symbiotic relationship exists between the intestinal microbiota and its host. A critical component of gut homeostasis is the presence of a mucus layer…”
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Shiga toxin interaction with human intestinal epithelium
Published in Toxins (01-06-2011)“…After ingestion via contaminated food or water, enterohaemorrhagic E. coli colonises the intestinal mucosa and produces Shiga toxins (Stx). No Stx-specific…”
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Journal Article Book Review -
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Intestinal Colonization Traits of Pandemic Multidrug-Resistant Escherichia coli ST131
Published in The Journal of infectious diseases (14-08-2018)“…Epidemiological studies point to the gut as a key reservoir of multidrug resistant Escherichia coli multilocus sequence type 131 (ST131), a globally dominant…”
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Translocation of outer membrane vesicles from enterohemorrhagic Escherichia coli O157 across the intestinal epithelial barrier
Published in Frontiers in microbiology (25-05-2023)“…Outer membrane vesicles (OMVs) carrying virulence factors of enterohemorrhagic (EHEC) are assumed to play a role in the pathogenesis of life-threatening…”
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A nanobody targeting the translocated intimin receptor inhibits the attachment of enterohemorrhagic E. coli to human colonic mucosa
Published in PLoS pathogens (29-08-2019)“…Enterohemorrhagic E. coli (EHEC) is a human intestinal pathogen that causes hemorrhagic colitis and hemolytic uremic syndrome. No vaccines or specific…”
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Development of a novel human intestinal model to elucidate the effect of anaerobic commensals on Escherichia coli infection
Published in Disease models & mechanisms (01-04-2022)“…The gut microbiota plays a crucial role in protecting against enteric infection. However, the underlying mechanisms are largely unknown owing to a lack of…”
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Shiga toxin 2 translocation across intestinal epithelium is linked to virulence of Shiga toxin-producing Escherichia coli in humans
Published in Microbiology (Society for General Microbiology) (01-04-2018)“…Shiga toxin-producing Escherichia coli (STEC) are characterized by the release of potent Shiga toxins (Stx), which are associated with severe intestinal and…”
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Probing Clostridium difficile Infection in Complex Human Gut Cellular Models
Published in Frontiers in microbiology (30-04-2019)“…Interactions of anaerobic gut bacteria, such as , with the intestinal mucosa have been poorly studied due to challenges in culturing anaerobes with the…”
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The StcE metalloprotease of enterohaemorrhagic Escherichia coli reduces the inner mucus layer and promotes adherence to human colonic epithelium ex vivo
Published in Cellular microbiology (01-06-2017)“…Enterohaemorrhagic Escherichia coli (EHEC) is a major foodborne pathogen and tightly adheres to human colonic epithelium by forming attaching/effacing lesions…”
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Modulation of Enterohaemorrhagic Escherichia coli Survival and Virulence in the Human Gastrointestinal Tract
Published in Microorganisms (Basel) (19-11-2018)“…Enterohaemorrhagic (EHEC) is a major foodborne pathogen responsible for human diseases ranging from diarrhoea to life-threatening complications. Survival of…”
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Identification and characterisation of enteroaggregative Escherichia coli subtypes associated with human disease
Published in Scientific reports (04-05-2020)“…Enteroaggregative E. coli (EAEC) are a major cause of diarrhoea worldwide. Due to their heterogeneity and carriage in healthy individuals, identification of…”
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Attaching and effacing (A/E) lesion formation by enteropathogenic E. coli on human intestinal mucosa is dependent on non-LEE effectors
Published in PLoS pathogens (01-10-2017)“…Enteropathogenic E. coli (EPEC) is a human pathogen that causes acute and chronic pediatric diarrhea. The hallmark of EPEC infection is the formation of…”
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Microaerobic conditions enhance type III secretion and adherence of enterohaemorrhagic Escherichia coli to polarized human intestinal epithelial cells
Published in Environmental microbiology (01-09-2010)“…Advances in the understanding of the pathogenesis of enterohaemorrhagic Escherichia coli (EHEC) have greatly benefited from the use of human epithelial cell…”
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Oxygen and contact with human intestinal epithelium independently stimulate virulence gene expression in enteroaggregative Escherichia coli
Published in Cellular microbiology (01-06-2019)“…Enteroaggregative Escherichia coli (EAEC) are important intestinal pathogens causing acute and persistent diarrhoeal illness worldwide. Although many putative…”
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Potent Diarrheagenic Mechanism Mediated by the Cooperative Action of Three Enteropathogenic Escherichia coli-Injected Effector Proteins
Published in Proceedings of the National Academy of Sciences - PNAS (07-02-2006)“…Enteropathogenic Escherichia coli (EPEC) induces a severe watery diarrhea responsible for several hundred thousand infant deaths each year by a process…”
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Shiga toxin production and translocation during microaerobic human colonic infection with Shiga toxin-producing E.coliO157:H7 and O104:H4
Published in Cellular microbiology (2014)“…Summary Haemolytic uraemic syndrome caused by Shiga toxin-producing E.coli (STEC) is dependent on release of Shiga toxins (Stxs) during intestinal infection…”
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The Intriguing Interaction of Escherichia coli with the Host Environment and Innovative Strategies To Interfere with Colonization: a Summary of the 2019 E. coli and the Mucosal Immune System Meeting
Published in Applied and environmental microbiology (24-11-2020)“…The third and the Mucosal Immune System (ECMIS) meeting was held at Ghent University in Belgium from 2 to 5 June 2019. It brought together an international…”
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The Escherichia coli Common Pilus and the Bundle-Forming Pilus Act in Concert during the Formation of Localized Adherence by Enteropathogenic E. coli
Published in Journal of Bacteriology (01-06-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Tir phosphorylation and Nck/N‐WASP recruitment by enteropathogenic and enterohaemorrhagic Escherichia coli during ex vivo colonization of human intestinal mucosa is different to cell culture models
Published in Cellular microbiology (01-05-2007)“…Summary Tir, the translocated intimin receptor of enteropathogenic and enterohaemorrhagic Escherichia coli (EPEC and EHEC) and Citrobacter rodentium, is…”
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Flagellin Induces β-Defensin 2 in Human Colonic Ex vivo Infection with Enterohemorrhagic Escherichia coli
Published in Frontiers in cellular and infection microbiology (21-06-2016)“…Enterohemorrhagic E.coli (EHEC) is an important foodborne pathogen in the developed world and can cause life-threatening disease particularly in children. EHEC…”
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