Search Results - "SCARLATO, Vincenzo"
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Regulation of heat-shock genes in bacteria: from signal sensing to gene expression output
Published in FEMS microbiology reviews (01-07-2017)“…Abstract The heat-shock response is a mechanism of cellular protection against sudden adverse environmental growth conditions and results in the prompt…”
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The Interplay between Two Transcriptional Repressors and Chaperones Orchestrates Helicobacter pylori Heat-Shock Response
Published in International journal of molecular sciences (07-06-2018)“…The ability to gauge the surroundings and modulate gene expression accordingly is a crucial feature for the survival bacterial pathogens. In this respect, the…”
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3
Insights into the Orchestration of Gene Transcription Regulators in Helicobacter pylori
Published in International journal of molecular sciences (08-11-2022)“…Bacterial pathogens employ a general strategy to overcome host defenses by coordinating the virulence gene expression using dedicated regulatory systems that…”
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Definition of the Binding Architecture to a Target Promoter of HP1043, the Essential Master Regulator of Helicobacter pylori
Published in International journal of molecular sciences (01-08-2021)“…HP1043 is an essential orphan response regulator of Helicobacter pylori orchestrating multiple crucial cellular processes. Classified as a member of the…”
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5
Targeting of Regulators as a Promising Approach in the Search for Novel Antimicrobial Agents
Published in Microorganisms (Basel) (15-01-2022)“…Since the discovery of penicillin in the first half of the last century, antibiotics have become the pillars of modern medicine for fighting bacterial…”
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6
Levofloxacin and Ciprofloxacin Co-Crystals with Flavonoids: Solid-State Investigation for a Multitarget Strategy against Helicobacter pylori
Published in Pharmaceutics (30-01-2024)“…In this paper, we address the problem of antimicrobial resistance in the case of with a crystal engineering approach. Two antibiotics of the fluoroquinolone…”
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In depth analysis of the Helicobacter pylori cag pathogenicity island transcriptional responses
Published in PloS one (03-06-2014)“…The severity of symptoms elicited by the widespread human pathogen Helicobacter pylori is strongly influenced by the genetic diversity of the infecting strain…”
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Feeling the Heat: The Campylobacter jejuni HrcA Transcriptional Repressor Is an Intrinsic Protein Thermosensor
Published in Biomolecules (Basel, Switzerland) (27-09-2021)“…The heat-shock response, a universal protective mechanism consisting of a transcriptional reprogramming of the cellular transcriptome, results in the…”
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In the NadR Regulon, Adhesins and Diverse Meningococcal Functions Are Regulated in Response to Signals in Human Saliva
Published in Journal of Bacteriology (01-01-2012)“…The Neisseria meningitidis regulator NadR was shown to repress expression of the NadA adhesin and play a major role in NadA phase-variable expression. In this…”
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10
Deconvolution of intergenic polymorphisms determining high expression of Factor H binding protein in meningococcus and their association with invasive disease
Published in PLoS pathogens (01-03-2021)“…Neisseria meningitidis is a strictly human pathogen and is the major cause of septicemia and meningitis worldwide. Factor H binding protein (fHbp) is a…”
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Cooperative Regulation of Campylobacter jejuni Heat-Shock Genes by HspR and HrcA
Published in Microorganisms (Basel) (30-07-2020)“…The heat-shock response is defined by the transient gene-expression program that leads to the rapid accumulation of heat-shock proteins. This evolutionary…”
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12
Built shallow to maintain homeostasis and persistent infection: insight into the transcriptional regulatory network of the gastric human pathogen Helicobacter pylori
Published in PLoS pathogens (01-06-2010)“…Transcriptional regulatory networks (TRNs) transduce environmental signals into coordinated output expression of the genome. Accordingly, they are central for…”
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Absence of Protein A Expression Is Associated With Higher Capsule Production in Staphylococcal Isolates
Published in Frontiers in microbiology (10-05-2019)“…is a major human pathogen, and a leading cause of soft tissue and blood stream infections. One of the causes of its success as a pathogen is the peculiar array…”
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14
Expression of Factor H Binding Protein of Meningococcus Responds to Oxygen Limitation through a Dedicated FNR-Regulated Promoter
Published in Journal of Bacteriology (01-02-2010)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
Targeting the Essential Transcription Factor HP1043 of Helicobacter pylori : A Drug Repositioning Study
Published in Frontiers in molecular biosciences (11-05-2022)“…Antibiotic-resistant bacterial pathogens are a very challenging problem nowadays. is one of the most widespread and successful human pathogens since it…”
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16
The Helicobacter pylori HspR-Modulator CbpA Is a Multifunctional Heat-Shock Protein
Published in Microorganisms (Basel) (13-02-2020)“…The medically important human pathogen relies on a collection of highly conserved heat-shock and chaperone proteins to preserve the integrity of cellular…”
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The Helicobacter pylori Heat-Shock Repressor HspR: Definition of Its Direct Regulon and Characterization of the Cooperative DNA-Binding Mechanism on Its Own Promoter
Published in Frontiers in microbiology (14-08-2018)“…The ability of pathogens to perceive environmental conditions and modulate gene expression accordingly is a crucial feature for bacterial survival. In this…”
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18
Global transcriptome analysis reveals small RNAs affecting Neisseria meningitidis bacteremia
Published in PloS one (07-05-2015)“…Most bacterial small RNAs (sRNAs) are post-transcriptional regulators involved in adaptive responses, controlling gene expression by modulating translation or…”
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Helicobacter pylori Stress-Response: Definition of the HrcA Regulon
Published in Microorganisms (Basel) (11-10-2019)“…Bacteria respond to different environmental stresses by reprogramming the transcription of specific genes whose proper expression is critical for their…”
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In Vivo Dissection of the Helicobacter pylori Fur Regulatory Circuit by Genome-Wide Location Analysis
Published in Journal of Bacteriology (01-07-2006)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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