Search Results - "SCALZO, REBECCA L."
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Glucose Uptake by Skeletal Muscle within the Contexts of Type 2 Diabetes and Exercise: An Integrated Approach
Published in Nutrients (03-02-2022)“…Type 2 diabetes continues to negatively impact the health of millions. The inability to respond to insulin to clear blood glucose (insulin resistance) is a key…”
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Sex Differences in the Skeletal Muscle Response to a High Fat, High Sucrose Diet in Rats
Published in Nutrients (01-10-2023)“…Men are diagnosed with type 2 diabetes at lower body mass indexes than women; the role of skeletal muscle in this sex difference is poorly understood. Type 2…”
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Regulators of human white adipose browning: evidence for sympathetic control and sexual dimorphic responses to sprint interval training
Published in PloS one (06-03-2014)“…The conversion of white adipose to the highly thermogenic beige adipose tissue has been proposed as a potential strategy to counter the unfavorable…”
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Mechanisms of Aerobic Exercise Impairment in Diabetes: A Narrative Review
Published in Frontiers in endocrinology (Lausanne) (18-04-2018)“…The prevalence of diabetes in the United States and globally has been rapidly increasing over the last several decades. There are now estimated to be 30.3…”
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Type 2 diabetes is linked to higher physiologic markers of effort during exercise
Published in Frontiers in clinical diabetes and healthcare (online) (29-04-2024)“…People with type 2 diabetes (T2D) have lower rates of physical activity (PA) than the general population. This is significant because insufficient PA is linked…”
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Liposomal-encapsulated Ascorbic Acid: Influence on Vitamin C Bioavailability and Capacity to Protect Against Ischemia-Reperfusion Injury
Published in Nutrition and Metabolic Insights (01-01-2016)“…Intravenous administration of vitamin C has been shown to decrease oxidative stress and, in some instances, improve physiological function in adult humans…”
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Acute vitamin C improves cardiac function, not exercise capacity, in adults with type 2 diabetes
Published in Diabetology and metabolic syndrome (14-02-2018)“…People with type 2 diabetes (T2D) have impaired exercise capacity, even in the absence of complications, which is predictive of their increased cardiovascular…”
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Concurrent Beet Juice and Carbohydrate Ingestion: Influence on Glucose Tolerance in Obese and Nonobese Adults
Published in Journal of nutrition and metabolism (01-01-2017)“…Insulin resistance and obesity are characterized by low nitric oxide (NO) bioavailability. Insulin sensitivity is improved with stimulation of NO generating…”
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Glucagon‐like peptide‐1 receptor antagonism impairs basal exercise capacity and vascular adaptation to aerobic exercise training in rats
Published in Physiological reports (01-07-2018)“…Cardiorespiratory fitness (CRF) inversely predicts cardiovascular (CV) mortality and CRF is impaired in people with type 2 diabetes (T2D). Aerobic exercise…”
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Diabetes mellitus in breast cancer survivors: metabolic effects of endocrine therapy
Published in Nature reviews. Endocrinology (01-01-2024)“…Breast cancer is the most common invasive malignancy in the world, with millions of survivors living today. Type 2 diabetes mellitus (T2DM) is also a globally…”
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Persistent Metabolic Effects of Tamoxifen: Considerations for an Experimental Tool and Clinical Breast Cancer Treatment
Published in Endocrinology (Philadelphia) (01-09-2021)“…The selective estrogen receptor (ER) modulator tamoxifen is frequently used in preclinical studies to induce Cre recombinase and generate conditional…”
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1372-P: Hyperglycemia Impacts Mouse Skeletal Muscle in a Sex-Specific Manner
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Functional Exercise Capacity (FEC) , a universal predictor of cardiovascular and all-cause mortality, is lower in adults and youth with diabetes for reasons…”
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305-OR: Short-Term Hyperglycemia Impacts Mouse Skeletal Muscle in a Sex-Specific Manner
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Cardiorespiratory Fitness (CRF) a universal predictor of cardiovascular and all-cause mortality, is lower in people with diabetes. Skeletal muscle is a key…”
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Total daily energy expenditure is increased following a single bout of sprint interval training
Published in Physiological reports (01-10-2013)“…Regular endurance exercise is an effective strategy for healthy weight maintenance, mediated via increased total daily energy expenditure (TDEE), and possibly…”
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1369-P: The Differential Effects of Estrogen on Determinants of Skeletal Muscle Bioenergetics with a High-Fat, High-Sucrose Diet in Rats
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Estrogen is a powerful, beneficial regulator of skeletal muscle mitochondria. Premenopausal women with type 2 diabetes (T2D) have relatively greater…”
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The Effects of Sympathetic Inhibition on Metabolic and Cardiopulmonary Responses to Exercise in Hypoxic Conditions
Published in Wilderness & environmental medicine (01-12-2015)“…Objective Pre-exertion skeletal muscle glycogen content is an important physiological determinant of endurance exercise performance: low glycogen stores…”
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1635-P: Sex Differences in Skeletal Muscle Mitochondrial Function in Rats Fed a High-Fat/High-Sucrose Diet
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Women maintain their metabolic health at greater body mass indexes compared with men, delaying the onset of type 2 diabetes (T2D). Skeletal muscle is…”
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245-OR: Age and Diabetes Interact to Decrease Muscle Mitochondrial Function
Published in Diabetes (New York, N.Y.) (01-06-2022)“…People with T2D have lower cardiorespiratory fitness (CRF) than those without diabetes contributing to increased cardiovascular morbidity and mortality. People…”
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598-P: No Relationship between Sedentary Behavior Patterns and Peak Oxygen Consumption (VO2peak) among Overweight Individuals With and Without Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Background: Sedentary behavior (SB) has negative effects on health, even in the context of achieving physical activity (PA) guidelines. It is unclear how total…”
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Greater muscle protein synthesis and mitochondrial biogenesis in males compared with females during sprint interval training
Published in The FASEB journal (01-06-2014)“…ABSTRACT Improved endurance exercise performance in adult humans after sprint interval training (SIT) has been attributed to mitochondrial biogenesis. However,…”
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