Search Results - "SAYLOR, David M"

Polymer degradation and drug delivery in PLGA-based drug-polymer applications: A review of experiments and theories by Xu, Yihan, Kim, Chang-Soo, Saylor, David M, Koo, Donghun

“…Poly (lactic-co-glycolic acid) (PLGA) copolymers have been broadly used in controlled drug release applications. Because these polymers are biodegradable, they…”
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Study on the design method of equal strength rim based on stress and fatigue analysis using finite element method by Chen, Lei, Li, Shunping, Chen, Huiqin, Saylor, David M, Tong, Shuiguang

“…Wheels are important safety components in the vehicle driving system. Automobile lightweight is the direction of the modern automobile development. In this…”
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Distribution of grain boundaries in magnesia as a function of five macroscopic parameters by Saylor, David M., Morawiec, Adam, Rohrer, Gregory S.

“…A semi-automated method has been used to measure all five macroscopically observable parameters of 4.1×10 6 boundary plane segments making up 5.4 mm 2 of…”
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The relative free energies of grain boundaries in magnesia as a function of five macroscopic parameters by Saylor, David M., Morawiec, Adam, Rohrer, Gregory S.

“…Using measurements of the geometric and crystallographic characteristics of approximately 10 4 triple junctions in a MgO polycrystal, the relative grain…”
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Distribution of grain boundaries in aluminum as a function of five macroscopic parameters by Saylor, David M, El Dasher, Bassem S, Rollett, Anthony D, Rohrer, Gregory S

“…The grain boundary character distribution in commercially pure Al has been measured as a function of lattice misorientation and boundary plane orientation. The…”
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Homology metrics for microstructure response fields in polycrystals by Wanner, Thomas, Fuller, Edwin R., Saylor, David M.

“…Quantitative homology metrics are proposed for characterizing the thermal–elastic response of polycrystalline materials. Simulations for a calcite-based…”
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Measuring the five-parameter grain-boundary distribution from observations of planar sections by SAYLOR, David M, EL-DASHER, Bassem S, ADAMS, Brent L, ROHRER, Gregory S

“…A stereological method is described for estimating the distribution of grain-boundary types in polycrystalline materials on the basis of observations from a…”
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Surface Energy Anisotropy of SrTiO3 at 1400°C in Air by Sano, Tomoko, Saylor, David M., Rohrer, Gregory S.

“…Geometric and crystallographic measurements of grain‐boundary thermal grooves and surface faceting behavior as a function of orientation have been used to…”
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Predicting Solute Diffusivity in Polymers Using Time–Temperature Superposition by Elder, Robert M., Saylor, David M.

“…We demonstrate a novel application of the time–temperature superposition (TTS) principle to predict solute diffusivity D in glassy polymers using atomistic…”
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Implications of variability on medical device chemical equivalence assessment by Saylor, David M., Young, Joshua A.

“…Chemical equivalence testing can be used to assess the biocompatibility implications of a materials or manufacturing change for a medical device. This testing…”
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Relations Between Dynamic Localization and Solute Diffusion in Polymers by Elder, Robert M, Saylor, David M

“…Various public health concerns can arise from the unintended leaching of additives and impurities from polymeric medical devices or food packaging, which is…”
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Distribution of Grain Boundaries in SrTiO3 as a Function of Five Macroscopic Parameters by Saylor, David M., El Dasher, Bassem, Sano, Tomoko, Rohrer, Gregory S.

“…Measurements of the grain boundary population as a function of misorientation and boundary plane orientation show that the distribution is inversely correlated…”
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Modeling extraction of medical device polymers for biocompatibility evaluation by Saylor, David M., Young, Joshua A.

“…Extraction testing is critical for biocompatibility evaluation of medical devices, whether to generate samples for biological testing or form the basis for…”
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Polymer-Interface-Tissue Model to Estimate Leachable Release from Medical Devices by Tanaka, Martin L, Saylor, David M, Elder, Robert M

“…The ability to predict clinically relevant exposure to potentially hazardous compounds that can leach from polymeric components can help reduce testing needed…”
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Habits of Grains in Dense Polycrystalline Solids by Saylor, David M., El Dasher, Bassem, Pang, Ying, Miller, Herbert M., Wynblatt, Paul, Rollett, Anthony D., Rohrer, Gregory S.

“…We show here that the boundaries of individual grains in dense polycrystals prefer certain crystallographic habit planes, almost as if they were independent of…”
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Measuring the Influence of Grain-Boundary Misorientation on Thermal Groove Geometry in Ceramic Polycrystals by Saylor, David M., Rohrer, Gregory S.

“…We have used electron backscattered diffraction patterns to determine the misorientation of 201 adjacent pairs of grains in a magnesia polycrystal. The width…”
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Residual-Stress Predictions in Polycrystalline Alumina by Vedula, Venkata R., Glass, S. Jill, Saylor, David M., Rohrer, Gregory S., Carter, W. Craig, Langer, Stephen A., Fuller Jr, Edwin R.

“…Microstructure‐level residual stresses occur in polycrystalline ceramics during processing, as a result of thermal expansion anisotropy and crystallographic…”
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Strategies for Rapid Risk Assessment of Color Additives Used in Medical Devices by Saylor, David M, Chandrasekar, Vaishnavi, Simon, David D, Turner, Paul, Markley, Laura C, Hood, Alan M

“…Many polymeric medical devices contain color additives for differentiation or labeling. Although some additives can be toxic under certain conditions, the risk…”
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Leveraging Extraction Testing to Predict Patient Exposure to Polymeric Medical Device Leachables Using Physics-based Models by Turner, Paul, Elder, Robert M, Nahan, Keaton, Talley, Anne, Shah, Saloni, Duncan, Timothy V, Sussman, Eric M, Saylor, David M

“…Toxicological risk assessment approaches are increasingly being used in lieu of animal testing to address toxicological concerns associated with release of…”
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Inter-laboratory study for extraction testing of medical devices by Saylor, David M., Elder, Robert M., Duelge, Kaleb, Ranasinghe Arachchige, Nimesh P.R., Simon, David D., Wickramasekara, Samanthi, Young, Joshua A.

“…Biocompatibility evaluation of medical devices often relies on chemical testing according to ISO 10993–18 as a critical component for consideration. However,…”
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