Search Results - "SAX, C. M"

A complex array of positive and negative elements regulates the chicken alpha A-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins by Cvekl, A, Sax, C M, Bresnick, E H, Piatigorsky, J

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Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene by Cvekl, A, Sax, C M, Li, X, McDermott, J B, Piatigorsky, J

“…The abundance of delta-crystallin in the chicken eye lens provides an advantageous marker for tissue-specific gene expression during cellular differentiation…”
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Transcriptional regulation of the mouse alpha A-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site by Cvekl, Aleš, Kashanchi, Fatah, Sax, Christina M., Brady, John N., Piatigorsky, Joram

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Regulation of the mouse alpha A-crystallin gene: isolation of a cDNA encoding a protein that binds to a cis sequence motif shared with the major histocompatibility complex class I gene and other genes by NAKAMURA, T, DONOVAN, D. M, HAMADA, K, SAX, C. M, NORMAN, B, FLANAGAN, J. R, OZATO, K, WESTPHAL, H, PIATIGORSKY, J

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The cellular basis of corneal transparency: evidence for 'corneal crystallins' by Jester, J V, Moller-Pedersen, T, Huang, J, Sax, C M, Kays, W T, Cavangh, H D, Petroll, W M, Piatigorsky, J

“…In vivo corneal light scattering measurements using a novel confocal microscope demonstrated greatly increased backscatter from corneal stromal fibrocytes…”
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The Mouse Transketolase (TKT) Gene: Cloning, Characterization, and Functional Promoter Analysis by Salamon, Csaba, Chervenak, Matthew, Piatigorsky, Joram, Sax, Christina M.

“…The transketolase (TKT) gene is expressed 30–50 times more highly in the mature mouse cornea than in other tissues. Here, we have cloned and characterized the…”
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A negative element involved in vimentin gene expression by FARRELL, F. X, SAX, C. M, ZEHNER, Z. E

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Expression of Crystallins, Pax6, Filensin, CP49, MIP, and MP20 in lens- derived cell lines by Krausz, E, Augusteyn, RC, Quinlan, RA, Reddan, JR, Russell, P, Sax, CM, Graw, J

“…Cell lines are the systems of choice to analyze cellular functions related to the particular organ system. For lens research, three cell lines are widely used:…”
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The chicken vimentin gene. Nucleotide sequence, regulatory elements, and comparison to the hamster gene by Zehner, Z E, Li, Y, Roe, B A, Paterson, B M, Sax, C M

“…Here we report the nucleotide sequence of the chicken vimentin gene and its deduced primary amino acid sequence. A comparison of this gene to other…”
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Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization by SAX, C. M, KLEMENT, J. F, PIATIGORSKY, J

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Functional redundancy of the DE-1 and αA-CRYBP1 regulatory sites of the mouse αA-crystallin promoter by Sax, Christina M., Iiagan, John G., Piatigorsky, Joram

“…Previous studies have implicated the DE-1 (−111/−106) and αA-CRYBP1 (−66/−57) sites for activity of the mouse αA-crystallin promoter in transiently transfected…”
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Down-regulation of vimentin gene expression during myogenesis is controlled by a 5'-flanking sequence by Sax, C M, Farrell, F X, Zehner, Z E

“…During myogenesis, the intermediate filament proteins vimentin and desmin are differentially expressed. While desmin levels increase dramatically, vimentin…”
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Multiple elements are required for expression of an intermediate filament gene by SAX, C. M, FARRELL, F. X, TOBIAN, J. A, ZEHNER, Z. E

“…The expression of vimentin is unique within the intermediate filament multigene family. It is the only member which deviates from its usual tissue-specific…”
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Conservation of mouse αA-crystallin promoter activity in chicken lens epithelial cells by DONOVAN, D. M, SAX, C. M, KLEMENT, J. F, XUAN LI, CHEPELINSKY, A. B, PIATIGORSKY, J

“…Previous transfection experiments have shown that 162 base pairs (bp) of the 5' flanking sequence of the chicken alpha A-crystallin gene are required for…”
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Functional analysis of chicken vimentin distal promoter regions in cultured lens cells by Sax, C M, Stover, D M, Ilagan, J G, Zehner, Z E, Piatigorsky, J

“…Synthesis of the cytoskeletal intermediate filament protein vimentin (Vim) in the lens is unexpected due to the mesenchymal preference of Vim-encoding gene…”
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Transketolase Is a Major Protein in the Mouse Cornea by Sax, Christina M., Salamon, Csaba, Kays, W. Todd, Guo, Jing, Yu, Fushin X., Cuthbertson, R. Andrew, Piatigorsky, Joram

“…Earlier experiments in this laboratory identified a highly expressed 65-68-kDa protein in both mouse and human corneas (Cuthbertson, R. A., Tomarev, S. I., and…”
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Regulation of alpha A-crystallin Gene Expression: Lens Specificity Achieved Through the Differential Placement of Similar Transcriptional Control Elements in Mouse and Chicken by Ilagan, J G, Cvekl, A, Kantorow, M, Piatigorsky, J, Sax, C M

“…The lens-preferred mouse alpha A-crystallin gene contains a conserved stretch (proximal element 2, +24/+43) in its 5'-noncoding region that we have previously…”
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Transketolase Gene Expression in the Cornea Is Influenced by Environmental Factors and Developmentally Controlled Events by Sax, Christina M, Kays, W Todd, Salamon, Csaba, Chervenak, Matthew M, Xu, Yong-Sheng, Piatigorsky, Joram

“…PURPOSE.Transketolase (TKT) has been proposed to be a corneal crystallin, and its gene and protein are abundantly expressed in the corneal epithelium of…”
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Craniofrontonasal dysplasia: clinical and genetic analysis by Sax, C M, Flannery, D B

“…We have identified a case of craniofrontonasal dysplasia which demonstrates the potential lethality of this gene. Genetic analysis of this pedigree and nine…”
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Protein-DNA interactions of the mouse alpha A-crystallin control regions. Differences between expressing and non-expressing cells by Kantorow, M, Cvekl, A, Sax, C M, Piatigorsky, J

“…Genomic footprinting, in vitro footprinting and mobility shift assays were used to investigate the molecular basis for expression of mouse alpha A-crystallin,…”
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