Search Results - "SAWADA, TOHRU"

Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial by Shinohara, Yukito, Prof, Katayama, Yasuo, Prof, Uchiyama, Shinichiro, Prof, Yamaguchi, Takenori, MD, Handa, Shunnosuke, Prof, Matsuoka, Kempei, MD, Ohashi, Yasuo, Prof, Tanahashi, Norio, Prof, Yamamoto, Hiroko, MD, Genka, Chokoh, MD, Kitagawa, Yasuhisa, Prof, Kusuoka, Hideo, MD, Nishimaru, Katsuya, MD, Tsushima, Motoo, MD, Koretsune, Yukihiro, MD, Sawada, Tohru, MD, Hamada, Chikuma, Prof

“…Summary Background The antiplatelet drug cilostazol is efficacious for prevention of stroke recurrence compared with placebo. We designed the second Cilostazol…”
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Cilostazol stroke prevention study: A placebo-controlled double-blind trial for secondary prevention of cerebral infarction by Gotoh, Fumio, Tohgi, Hideo, Hirai, Shunsaku, Terashi, Akiro, Fukuuchi, Yasuo, Otomo, Eiichi, Shinohara, Yukito, Itoh, Eiichi, Matsuda, Tamotsu, Sawada, Tohru, Yamaguchi, Takenori, Nishimaru, Katsuya, Ohashi, Yasuo

“…Cilostazol, an antiplatelet drug that increases the cyclic adenosine monophosphate (AMP) levels in platelets via inhibition of cyclic AMP phosphodiesterase,…”
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Functional imaging of gustatory perception and imagery: “top-down” processing of gustatory signals by Kobayashi, Masayuki, Takeda, Masaki, Hattori, Noriaki, Fukunaga, Masaki, Sasabe, Tetsuya, Inoue, Noriko, Nagai, Yasuo, Sawada, Tohru, Sadato, Norihiro, Watanabe, Yasuyoshi

“…By recalling gustatory memories, it is possible to generate vivid gustatory perceptions in the absence of gustatory inputs. This gustatory image influences our…”
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Proton MR spectroscopic study at 3 Tesla on glutamate/glutamine in Alzheimerʼs disease by Hattori, Noriaki, Abe, Kazuo, Sakoda, Saburo, Sawada, Tohru

“…To investigate metabolic changes in Alzheimerʼs disease (AD), we performed proton MR spectroscopy at 3 T. Spectra were acquired from the gray matter of the…”
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Endogenous dopamine release induced by repetitive transcranial magnetic stimulation over the primary motor cortex: an [11C]raclopride positron emission tomography study in anesthetized macaque monkeys by Ohnishi, Takashi, Hayashi, Takuya, Okabe, Shingo, Nonaka, Ikuo, Matsuda, Hiroshi, Iida, Hidehiro, Imabayashi, Etsuko, Watabe, Hiroshi, Miyake, Yoshihiro, Ogawa, Mikako, Teramoto, Noboru, Ohta, Yoichirou, Ejima, Norimasa, Sawada, Tohru, Ugawa, Yoshikazu

“…Repetitive transcranial magnetic stimulation (rTMS) has been used as a treatment for neuropsychiatric disorders such as depression and Parkinson's disease…”
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Styrylbenzoazole derivatives for imaging of prion plaques and treatment of transmissible spongiform encephalopathies by Ishikawa, Kensuke, Kudo, Yukitsuka, Nishida, Noriyuki, Suemoto, Takahiro, Sawada, Tohru, Iwaki, Toru, Doh‐ura, Katsumi

“…Recent prevalence of acquired forms of transmissible spongiform encephalopathies (TSEs) has urged the development of early diagnostic measures as well as…”
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In vivo labeling of amyloid with BF-108 by Suemoto, Takahiro, Okamura, Nobuyuki, Shiomitsu, Tsuyoshi, Suzuki, Masako, Shimadzu, Hiroshi, Akatsu, Hiroyasu, Yamamoto, Takayuki, Kudo, Yukitsuka, Sawada, Tohru

“…Detection of aggregated amyloid-beta (Aβ) with a non-invasive imaging modality such as positron emission tomography (PET) was suggested to be ideal for the…”
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Amyloid imaging probes are useful for detection of prion plaques and treatment of transmissible spongiform encephalopathies by Ishikawa, Kensuke, Doh-ura, Katsumi, Kudo, Yukitsuka, Nishida, Noriyuki, Murakami-Kubo, Ikuko, Ando, Yukio, Sawada, Tohru, Iwaki, Toru

“…1 Department of Neuropathology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582,…”
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NF-κB Regulates B-Cell-Derived Nerve Growth Factor Expression by Klaus Heese Noriko Inoue Tohru Sawada

“…In the mammalian brain, four neurotrophins have been identified： nerve growth factor （NGF）, brain-derived neurotrophic factor （BDNF）, neurotrophin-3 （NT-3） and…”
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Long-term effect of motor cortical repetitive transcranial magnetic stimulation induces by Hayashi, Takuya, Ohnishi, Takashi, Okabe, Shingo, Teramoto, Noboru, Nonaka, Yukio, Watabe, Hiroshi, Imabayashi, Etsuko, Ohta, Yoichiro, Jino, Hiroshi, Ejima, Norimasa, Sawada, Tohru, Iida, Hidehiro, Matsuda, Hiroshi, Ugawa, Yoshikazu

“…Repetitive transcranial magnetic stimulation (rTMS) recently has been assessed as a noninvasive treatment modality for movement and psychiatric disorders,…”
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Oligodendroglial cell death with DNA fragmentation in the white matter under chronic cerebral hypoperfusion: comparison between normotensive and spontaneously hypertensive rats by Masumura, Makoto, Hata, Ryuji, Nagai, Yasuo, Sawada, Tohru

“…We investigated the neuropathological and biochemical changes in the white matter of normotensive Wistar Kyoto (WKY) and spontaneously hypertensive rats (SHR)…”
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Binding and safety profile of novel benzoxazole derivative for in vivo imaging of amyloid deposits in Alzheimer's disease by Okamura, Nobuyuki, Furumoto, Shozo, Funaki, Yoshihito, Suemoto, Takahiro, Kato, Motohisa, Ishikawa, Yoichi, Ito, Satoshi, Akatsu, Hiroyasu, Yamamoto, Takayuki, Sawada, Tohru, Arai, Hiroyuki, Kudo, Yukitsuka, Yanai, Kazuhiko

“…Background:  In vivo detection of amyloid deposits in the brain is potentially useful for early diagnosis of Alzheimer's disease (AD) and tracking the efficacy…”
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Functional anatomy of chemical senses in the alert monkey revealed by positron emission tomography by Kobayashi, Masayuki, Sasabe, Tetsuya, Takeda, Masaki, Kondo, Yusuke, Yoshikubo, Shin-ichi, Imamura, Kazuyuki, Onoe, Hirotaka, Sawada, Tohru, Watanabe, Yasuyoshi

“…Functional imaging technique using positron emission tomography (PET) has made it possible to localize functional brain regions in the human brain by detecting…”
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Identification of rTid-1, the rat homologue of the drosophila tumor suppressor l(2)tid gene by Fujita, Masako, Nagai, Yasuo, Sawada, Tohru, Heese, Klaus

“…Active cell death ('apoptosis' or 'programmed cell death') is essential in the development and homeostasis of multicellular organisms and abnormal inhibition…”
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Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain by Heese, Klaus, Nakayama, Takahiro, Hata, Ryuji, Masumura, Makoto, Akatsu, Hiroyasu, Li, Feng, Nagai, Yasuo, Yamamoto, Takayuki, Kosaka, Kenji, Suemoto, Takahiro, Sawada, Tohru

“…The treatment of Alzheimer's disease (AD) remains a major challenge because of the incomplete understanding of the triggering events that lead to the selective…”
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The splicing regulatory protein p18SRP is down-regulated in Alzheimer's disease brain by Heese, Klaus, Fujita, Masako, Akatsu, Hiroyasu, Yamamoto, Takayuki, Kosaka, Kenji, Nagai, Yasuo, Sawada, Tohru

“…Alzheimer's disease (AD) is the most common neurodegenerative disorder of aging, accounting for an estimated two-thirds of all cases of senile dementia. Using…”
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Vascular cognitive impairment by O'Brien, John T, Erkinjuntti, Timo, Reisberg, Barry, Roman, Gustavo, Sawada, Tohru, Pantoni, Leonardo, Bowler, John V, Ballard, Clive, DeCarli, Charles, Gorelick, Philip B, Rockwood, Kenneth, Burns, Alistair, Gauthier, Serge, DeKosky, Steven T

“…Cerebrovascular disease is the second most common cause of acquired cognitive impairment and dementia and contributes to cognitive decline in the…”
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Development of a Hyperpolarized 129Xe System on 3T for the Rat Lungs by SATO, Hiroshi, ENMI, Jun-ichiro, HAYASHI, Takuya, TAKEI, Naoyuki, IWADATE, Yuji, ABE, Sumiko, TERAMOTO, Noboru, KAWACHI, Naoki, HATTORI, Mineyuki, WATABE, Hiroshi, SAWADA, Tohru, UCHIYAMA, Katsumi, TSUKAMOTO, Tetsuji, NAGASAWA, Kiyoshi, IIDA, Hidehiro

“…MRI (magnetic resonance imaging) with 129Xe has gained much attention as a diagnostic methodology because of its affinity for lipids and possible polarization…”
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Benefit of cilostazol in patients with high risk of bleeding: subanalysis of cilostazol stroke prevention study 2 by Uchiyama, Shinichiro, Shinohara, Yukito, Katayama, Yasuo, Yamaguchi, Takenori, Handa, Shunnosuke, Matsuoka, Kempei, Ohashi, Yasuo, Tanahashi, Norio, Yamamoto, Hiroko, Genka, Chokoh, Kitagawa, Yasuhisa, Kusuoka, Hideo, Nishimaru, Katsuya, Tsushima, Motoo, Koretsune, Yukihiro, Sawada, Tohru, Hamada, Chikuma

“…The Cilostazol Stroke Prevention Study 2 (CSPS 2) showed that cilostazol significantly reduced the risk of stroke by 25.7% relative to aspirin, with…”
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Quinoline and Benzimidazole Derivatives: Candidate Probes for In Vivo Imaging of Tau Pathology in Alzheimer's Disease by Okamura, Nobuyuki, Suemoto, Takahiro, Furumoto, Shozo, Suzuki, Masako, Shimadzu, Hiroshi, Akatsu, Hiroyasu, Yamamoto, Takayuki, Fujiwara, Hironori, Nemoto, Miyako, Maruyama, Masahiro, Arai, Hiroyuki, Yanai, Kazuhiko, Sawada, Tohru, Kudo, Yukitsuka

“…Neurofibrillary tangles (NFTs), neuropil threads, and neuritic elements of senile plaques predominantly comprise hyperphosphorylated tau protein and represent…”
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