Search Results - "SAVRANSKY, Vladimir"

Chronic Intermittent Hypoxia Induces Atherosclerosis by Savransky, Vladimir, Nanayakkara, Ashika, Li, Jianguo, Bevans, Shannon, Smith, Philip L, Rodriguez, Annabelle, Polotsky, Vsevolod Y

“…Obstructive sleep apnea, a condition leading to chronic intermittent hypoxia (CIH), is associated with hyperlipidemia, atherosclerosis, and a high…”
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Current Status and Trends in Prophylaxis and Management of Anthrax Disease by Savransky, Vladimir, Ionin, Boris, Reece, Joshua

“…has been identified as a potential military and bioterror agent as it is relatively simple to produce, with spores that are highly resilient to degradation in…”
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Hyperlipidemia and lipid peroxidation are dependent on the severity of chronic intermittent hypoxia by Li, Jianguo, Savransky, Vladimir, Nanayakkara, Ashika, Smith, Philip L, O'Donnell, Christopher P, Polotsky, Vsevolod Y

“…1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; and 2 Division of…”
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Chronic intermittent hypoxia predisposes to liver injury by Savransky, Vladimir, Nanayakkara, Ashika, Vivero, Angelica, Li, Jianguo, Bevans, Shannon, Smith, Philip L., Torbenson, Michael S., Polotsky, Vsevolod Y.

“…Obstructive sleep apnea (OSA) is characterized by chronic intermittent hypoxia (CIH). OSA is associated with nonalcoholic steatohepatitis (NASH) in obese…”
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Chronic intermittent hypoxia causes hepatitis in a mouse model of diet-induced fatty liver by Savransky, Vladimir, Bevans, Shannon, Nanayakkara, Ashika, Li, Jianguo, Smith, Philip L, Torbenson, Michael S, Polotsky, Vsevolod Y

“…Obstructive sleep apnea (OSA) causes chronic intermittent hypoxia (CIH) during sleep. OSA is associated with nonalcoholic steatohepatitis (NASH) in obese…”
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Intermittent hypoxia has organ-specific effects on oxidative stress by Jun, Jonathan, Savransky, Vladimir, Nanayakkara, Ashika, Bevans, Shannon, Li, Jianguo, Smith, Philip L, Polotsky, Vsevolod Y

“…Obstructive sleep apnea is characterized by upper airway collapse, leading to intermittent hypoxia (IH). It has been postulated that IH-induced oxidative…”
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Dyslipidemia and Atherosclerosis Induced by Chronic Intermittent Hypoxia Are Attenuated by Deficiency of Stearoyl Coenzyme A Desaturase by Savransky, Vladimir, Jun, Jonathan, Li, Jianguo, Nanayakkara, Ashika, Fonti, Shannon, Moser, Ann B, Steele, Kimberly E, Schweitzer, Michael A, Patil, Susheel P, Bhanot, Sanjay, Schwartz, Alan R, Polotsky, Vsevolod Y

“…Obstructive sleep apnea leads to chronic intermittent hypoxia (CIH) and is associated with atherosclerosis. We have previously shown that C57BL/6J mice exposed…”
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Phenotypic and Functional Characterization of Kidney-Infiltrating Lymphocytes in Renal Ischemia Reperfusion Injury by Ascon, Dolores B, Lopez-Briones, Sergio, Liu, Manchang, Ascon, Miguel, Savransky, Vladimir, Colvin, Robert B, Soloski, Mark J, Rabb, Hamid

“…T and B lymphocytes have been implicated in the pathogenesis of renal ischemia reperfusion injury (IRI). The trafficking of lymphocytes into kidneys during IRI…”
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Intermittent and sustained hypoxia induce a similar gene expression profile in human aortic endothelial cells by Polotsky, Vsevolod Y, Savransky, Vladimir, Bevans-Fonti, Shannon, Reinke, Christian, Li, Jianguo, Grigoryev, Dmitry N, Shimoda, Larissa A

“…Obstructive sleep apnea may cause vascular inflammation and atherosclerosis, which has been attributed to intermittent hypoxia (IH). Recent data suggest that…”
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Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia by Li, Jianguo, Nanayakkara, Ashika, Jun, Jonathan, Savransky, Vladimir, Polotsky, Vsevolod Y

“…Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland Obstructive sleep…”
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Pathology and Pathophysiology of Inhalational Anthrax in a Guinea Pig Model by Savransky, Vladimir, Sanford, Daniel C, Syar, Emily, Austin, Jamie L, Tordoff, Kevin P, Anderson, Michael S, Stark, Gregory V, Barnewall, Roy E, Briscoe, Crystal M, Lemiale-Biérinx, Laurence, Park, Sukjoon, Ionin, Boris, Skiadopoulos, Mario H

“…OA  Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Keratinocyte-derived chemokine is an early biomarker of ischemic acute kidney injury by Molls, Roshni R, Savransky, Vladimir, Liu, Manchang, Bevans, Shannon, Mehta, Tulsi, Tuder, Rubin M, King, Landon S, Rabb, Hamid

“…Renal ischemia-reperfusion injury (IRI) is the leading cause of acute kidney injury [AKI; acute renal failure (ARF)] in native kidneys and delayed graft…”
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Restoring leptin signaling reduces hyperlipidemia and improves vascular stiffness induced by chronic intermittent hypoxia by Yang, Ronghua, Sikka, Gautam, Larson, Jill, Watts, Vabren L, Niu, Xiaolin, Ellis, Carla L, Miller, Karen L, Camara, Andre, Reinke, Christian, Savransky, Vladimir, Polotsky, Vsevolod Y, O'Donnell, Christopher P, Berkowitz, Dan E, Barouch, Lili A

“…Chronic intermittent hypoxia (IH) during sleep can result from obstructive sleep apnea (OSA), a disorder that is particularly prevalent in obesity. OSA is…”
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Chronic intermittent hypoxia and acetaminophen induce synergistic liver injury in mice by Savransky, Vladimir, Reinke, Christian, Jun, Jonathan, Bevans‐Fonti, Shannon, Nanayakkara, Ashika, Li, Jianguo, Myers, Allen C., Torbenson, Michael S., Polotsky, Vsevolod Y.

“…Obstructive sleep apnoea (OSA) leads to chronic intermittent hypoxia (CIH) during sleep. Obstructive sleep apnoea has been associated with liver injury…”
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Effective skin decontamination with RSDL® (reactive skin decontamination lotion kit) following dermal exposure to a Novichok class nerve agent by Cornelissen, Alex S., van den Berg, Roland M., Langenberg, Jan P., van Grol, Marco, Bross, Rowdy, Pittman, John, Cochrane, Laura, Savransky, Vladimir

“…In recent years, various poisoning incidents have been reported, involving the alleged use of the so-called Novichok agents, resulting in their addition to the…”
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Efficacy of the AV7909 anthrax vaccine candidate in guinea pigs and nonhuman primates following two immunizations two weeks apart by Shearer, Jeffry D., Henning, Lisa, Sanford, Daniel C., Li, Na, Skiadopoulos, Mario H., Reece, Joshua J., Ionin, Boris, Savransky, Vladimir

“…The anthrax vaccine candidate AV7909 is being developed as a next-generation vaccine for post-exposure prophylaxis (PEP) against inhalational anthrax. In…”
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Repeat-Dose Toxicity Study of a Lyophilized Recombinant Protective Antigen-Based Anthrax Vaccine Adjuvanted With CpG 7909 by Savransky, Vladimir, Lacy, Michael, Ionin, Boris, Skiadopoulos, Mario H., Shearer, Jeffry

“…A recombinant protective antigen (rPA) anthrax vaccine candidate (rPA7909) was developed as a next-generation vaccine indicated for postexposure prophylaxis of…”
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Obstructive Sleep Apnea, Insulin Resistance, and Steatohepatitis in Severe Obesity by Polotsky, Vsevolod Y, Patil, Susheel P, Savransky, Vladimir, Laffan, Alison, Fonti, Shannon, Frame, Leigh A, Steele, Kimberly E, Schweizter, Michael A, Clark, Jeanne M, Torbenson, Michael S, Schwartz, Alan R

“…Obstructive sleep apnea is associated with insulin resistance and liver injury. It is unknown whether apnea contributes to insulin resistance and…”
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Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model by Kentrop, Jiska, Savransky, Vladimir, Klaassen, Steven D., van Groningen, Tomas, Bohnert, Sara, Cornelissen, Alex S., Cochrane, Laura, Barry, John, Joosen, Marloes J.A.

“…Nerve agent exposure is generally treated by an antidote formulation composed of a muscarinic antagonist, atropine sulfate (ATR), and a reactivator of…”
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Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1α by Li, Jianguo, Bosch-Marce, Marta, Nanayakkara, Ashika, Savransky, Vladimir, Fried, Susan K., Semenza, Gregg L., Polotsky, Vsevolod Y.

“…We have previously shown that exposure of C57BL/6J mice to intermittent hypoxia (IH) leads to 1) hypertriglyceridemia due to upregulation of pathways of lipid…”
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