Search Results - "SAVIRANTA, Petri"
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Nanobody engineering for SARS-CoV-2 neutralization and detection
Published in Microbiology spectrum (02-04-2024)“…In response to the ongoing COVID-19 pandemic, the quest for coronavirus inhibitors has inspired research on a variety of small proteins beyond conventional…”
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A cell spot microarray method for production of high density siRNA transfection microarrays
Published in BMC genomics (28-03-2011)“…High-throughput RNAi screening is widely applied in biological research, but remains expensive, infrastructure-intensive and conversion of many assays to HTS…”
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ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome
Published in Nature methods (01-01-2007)“…ProteomeBinders is a new European consortium aiming to establish a comprehensive resource of well-characterized affinity reagents, including but not limited to…”
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Integrative Functional Genomics Analysis of Sustained Polyploidy Phenotypes in Breast Cancer Cells Identifies an Oncogenic Profile for GINS2
Published in Neoplasia (New York, N.Y.) (01-11-2010)“…Aneuploidy is among the most obvious differences between normal and cancer cells. However, mechanisms contributing to development and maintenance of aneuploid…”
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Evaluating Sandwich Immunoassays in Microarray Format in Terms of the Ambient Analyte Regime
Published in Clinical chemistry (Baltimore, Md.) (01-10-2004)“…Conceptionally, antibody microarrays are simply multiplexed sandwich immunoassays in a miniaturized format. However, from the amounts of capture antibodies…”
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Dual-Label Time-resolved Immunofluorometric Assay of Free and Total Prostate-specific Antigen Based on Recombinant Fab Fragments
Published in Clinical chemistry (Baltimore, Md.) (01-05-2000)“…Recombinant Fab fragments are attractive as reagents for novel sandwich immunoassays, but no such assays have been described. We developed a dual-label…”
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Real-time wash-free detection of unlabeled PNA-DNA hybridization using discrete FET sensor
Published in Scientific reports (16-11-2017)“…We demonstrate an electrochemical sensor for detection of unlabeled single-stranded DNA using peptide nucleic acid (PNA) probes coupled to the field-effect…”
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Quantitative Multianalyte Microarray Immunoassay Utilizing Upconverting Phosphor Technology
Published in Analytical chemistry (Washington) (16-10-2012)“…A quantitative multianalyte immunoassay utilizing luminescent upconverting single-crystal nanoparticles as reporters on an antibody array-in-well platform was…”
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Array-in-well binding assay for multiparameter screening of phage displayed antibodies
Published in Methods (San Diego, Calif.) (01-03-2017)“…•A simple assay concept for the fast determination of antibody activity and epitope using phage displayed antibodies.•A panel of synthetic antibody phage…”
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Array-in-well platform–based multiplex assay for the simultaneous detection of anti-HIV- and treponemal-antibodies, and Hepatitis B surface antigen
Published in Journal of immunological methods (01-02-2016)“…Multiplex assays detecting sets of related clinical analytes simultaneously can save considerable amount of time and resources. Array-in-well (AIW) is a…”
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Structural analysis of an anti-estradiol antibody
Published in Molecular immunology (01-11-1997)“…An anti-estradiol antibody with improved specificity is searched for by combining steroid analog binding studies, mutant antibodies obtained from a…”
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Real-time measurement of cell permeabilization with low-molecular-weight membranolytic agents
Published in Journal of antimicrobial chemotherapy (01-08-1995)“…A new method for studying the action of membranolytic agents by simple measurement of light emitted from cells is described. It is based on the expression of…”
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Oligonucleotide Array-in-Well Platform for Detection and Genotyping Human Adenoviruses by Utilizing Upconverting Phosphor Label Technology
Published in Analytical chemistry (Washington) (15-02-2011)“…We have developed a robust array-in-well test platform based on an oligonucleotide array, combining advantages of simple instrumentation and new upconverting…”
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Maternal gluten, cereal, and dietary fiber intake during pregnancy and lactation and the risk of islet autoimmunity and type 1 diabetes in the child
Published in Clinical nutrition ESPEN (01-08-2024)“…Maternal gluten intake in relation to child's risk of type 1 diabetes has been studied in few prospective studies considering the diet during pregnancy but…”
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Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: Systematic variation between sample types and calibration of mass spectrometry data
Published in Proteomics (Weinheim) (01-08-2005)“…Four different immunoassay and antibody microarray methods performed at four different sites were used to measure the levels of a broad range of proteins (N =…”
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Expression of prostate specific antigen on the surface of a filamentous phage
Published in Biochemical and biophysical research communications (16-05-1994)“…We have constructed two phagemid vectors containing the gene coding for human Prostate Specific Antigen (PSA) translationally fused to a pelB signal sequence…”
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Exposomic determinants of immune-mediated diseases: Special focus on type 1 diabetes, celiac disease, asthma, and allergies: The HEDIMED project approach
Published in Environmental epidemiology (01-06-2022)“…The incidence of immune-mediated diseases (IMDs) is increasing rapidly in the developed countries constituting a huge medical, economic, and societal…”
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Human Protein Atlas charts a diverse terrain
Published in Trends in biotechnology (Regular ed.) (01-05-2006)“…A complete set of high-quality antibodies against the human proteome would constitute a remarkable resource for the analysis of protein abundances in tissues,…”
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Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assay
Published in Molecular oncology (01-02-2011)“…Cell division is orchestrated by a complex protein network that aims to maintenance of genomic stability. Visualisation of mitotic protein–protein associations…”
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