Search Results - "SAVINOVA, O. V"

Addition of Cyanoethyl Groups to Ring a of Triterpenoids by Galaiko, N. V., Tolmacheva, I. A., Igosheva, E. V., Savinova, O. V., Grishko, V. V.

“…The potential for cyanoethylation of ring A of triterpenoids and their A-seco derivatives prepared from allobetulone and methyl betulonate was investigated…”
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Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function by Kim, Byong Su, Savinova, Olga V., Reedy, Mark V., Martin, Janice, Lun, Yi, Gan, Lin, Smith, Richard S., Tomarev, Stanislav I., John, Simon W. M., Johnson, Randy L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice [published erratum appears in Invest Ophthalmol Vis Sci 1998 Aug;39(9):1641] by John, SW, Smith, RS, Savinova, OV, Hawes, NL, Chang, B, Turnbull, D, Davisson, M, Roderick, TH, Heckenlively, JR

“…To characterize ocular abnormalities associated with iris atrophy in DBA/2J mice and to determine whether mice of this strain develop elevated intraocular…”
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Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development by SMITH, R. S, ZABALETA, A, KUME, T, SAVINOVA, O. V, KIDSON, S. H, MARTIN, J. E, NISHIMURA, D. Y, ALWARD, W. L. M, HOGAN, B. L. M, JOHN, S. W. M

“…Anterior segment developmental disorders, including Axenfeld-Rieger anomaly (ARA), variably associate with harmfully elevated intraocular pressure (IOP), which…”
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Synthesis and antiviral activity of C-3(C-28)-substituted 2,3-seco-triterpenoids by Tolmacheva, I. A, Igosheva, E. V, Savinova, O. V, Boreko, E. I, Grishko, V. V

“…Amide conjugates with four structural types of β-amino alcohols were synthesized from 2,3-seco-18αH-oleananoic and 2,3-seco-lupane C-3(C-28) mono- and…”
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Lupane triterpenes and derivatives with antiviral activity by Baltina, L A, Flekhter, O B, Nigmatullina, L R, Boreko, E I, Pavlova, N I, Nikolaeva, S N, Savinova, O V, Tolstikov, G A

“…Betulin and betulinic acid have been modified at the C-3 and C-28 positions and the antiviral activity of derivatives has been evaluated in vitro. It was found…”
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Synthesis and antiviralactivity of 2,3-seco-derivatives of betulonic acid by Tolmacheva, I. A, Grishko, V. V, Boreko, E. I, Savinova, O. V, Pavlova, N. I

“…A lupane 2,3-seco-aldehydoacid that was oxidized further to the 2,3-seco-diacid was synthesized by Beckmann fragmentation of the α-hydroxyoxime of betulonic…”
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Antiviral Activity of Acyl Derivatives of Betulin and Betulinic and Dihydroquinopimaric Acids by Kazakova, O. B., Smirnova, I. E., Baltina, L. A., Boreko, E. I., Savinova, O. V., Pokrovskii, A. G.

“…The paper reports on the synthesis of a series of acyl derivatives of betulin and dihydroquinopimaric acid and the study of their antiviral activity against…”
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Comparative Evaluation of the Antiherpes Activity of Compounds with Different Mechanisms of Action by Shadyro, O. I., Sorokin, V. L., Ksendzova, G. A., Savinova, O. V., Samovich, S. N., Boreko, E. I.

“…Experiments on cell cultures addressed the antiviral properties of 2-anilino-4,6-di- tert -butylphenol and N-(3,5-di- tert -2-hydroxyphenyl)acetamide, both of…”
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Regioselective Transformation of the Cyano Group of Triterpene α,β-Alkenenitriles by Konysheva, A. V., Tolmacheva, I. A., Savinova, O. V., Boreko, E. I., Grishko, V. V.

“…Unsaturated acids, including difficultly accessible ceanothane-type ones, were prepared via alkaline hydrolysis of semi-synthetic triterpenoids with 1-cyano-…”
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The Assessment of the Competitiveness of Adhesive Bandages Used in Peripheral Vascular Diseases in Geriatric Patients by Savinova, O V, Babaskin, D V, Krylova, O V, Udovichenko, E V, Winter, E A

“…The data found in the study on the impact and evaluation of research subjects allow identifying competitive advantages of different methods of the dressings'…”
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Modifying Factors of Transdermal Delivery of Biologically Active Substances of Peloid: Experimental Research by Babaskin, D V, Litvinova, T M, Babaskina, L I, Savinova, O V, Winter, E A

“…The kinetics of biologically active substances' (flavonoids) transdermal delivery from peat peloid compositions containing the phytocomplex have been studied…”
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Synthesis and Antiviral Activity of Hydroxy-Substituted Benzaldehydes and Related Compounds by Shadyro, O. I., Sorokin, V. L., Ksendzova, G. A., Savinova, O. V., Samovich, S. N., Pavlova, N. I., Polozov, G. I., Boreko, E. I.

“…A series of hydroxy-substituted benzaldehydes and related compounds were synthesized and studied in cell culture against herpes simplex type I (HSV-1) and…”
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Modification of Ocular Defects in Mouse Developmental Glaucoma Models by Tyrosinase by Libby, Richard T., Smith, Richard S., Savinova, Olga V., Zabaleta, Adriana, Martin, Janice E., Gonzalez, Frank J., Simon W. M. John

“…Mutations in the cytochrome P450 family 1, subfamily B, polypeptide 1 (CYP1B1) gene are a common cause of human primary congenital glaucoma (PCG). Here we show…”
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Synthesis and Pharmacological Activity of 20-Keto-29-norlupane Derivatives by Flekhter, O. B., Giniyatullina, G. V., Galin, F. Z., Baschenko, N. Zh, Makara, N. S., Zarudii, F. S., Boreko, E. I., Savinova, O. V., Pavlova, N. I., Starikova, Z. A., Tolstikov, G. A.

“…New 20-oxo- and hydroxyimino-derivatives of betulin that exhibit immunotropic and antiviral activities were synthesized…”
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Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses by Pavlova, N.I., Savinova, O.V., Nikolaeva, S.N., Boreko, E.I., Flekhter, O.B.

“…Antiviral properties of betulin, betulinic and betulonic acids were investigated in cell cultures infected with herpes simplex type I, influenza FPV/Rostock…”
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The mouse anterior chamber angle and trabecular meshwork develop without cell death by Smith, R S, Zabaleta, A, Savinova, O V, John, S W

“…The iridocorneal angle forms in the mammalian eye from undifferentiated mesenchyme between the root of the iris and cornea. A major component is the trabecular…”
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Betulonic amides modified at cycle a by amino acids: Synthesis and inhibition of flu A virus reproduction by Flekhter, O. B., Medvedeva, N. I., Tolstikov, G. A., Savinova, O. V., Boreko, E. I., Dolgushin, F. M.

“…The Beckman rearrangement of carboxy- and alkyloxycarbonylalkylamides of 3-hydroxyiminobetulonic acid led to derivatives of 3 a -homo-4-aza-3-oxolup-20(29)-ene…”
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Betulonic amides modified at the ring A by amino acids: synthesis and inhibition of influenza A virus reproduction by Flekhter, O B, Medvedeva, N I, Tolstikov, G A, Savinova, O V, Boreko, E I, Dolgushin, F M

“…The Beckman rearrangement of carboxy- and alkyloxycarbonylalkylamides of 3-hydroxyiminobetulonic acid led to derivatives of 3a-homo-4-aza-3-oxolup-20(29)-ene…”
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Synthesis and antiviral activity of lupane triterpenoids with modified cycle E by Flekhter, O. B., Medvedeva, N. I., Kukovinets, O. S., Spirikhin, L. V., Galkin, E. G., Galin, F. Z., Golovanov, D. G., Pavlova, N. I., Savinova, O. V., Boreko, E. I., Tolstikov, G. A.

“…A reductive transformation of the peroxide products of ozonolysis of derivatives of 3 beta -O-acetyl-22(17 arrow right 28)-abeo-lupa-17(28),20(29)-diene and…”
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