Search Results - "SAVIGNONI, Alexia"

A Question Prompt List for Advanced Cancer Patients Promoting Advance Care Planning: A French Randomized Trial by Bouleuc, Carole, Savignoni, Alexia, Chevrier, Marion, Renault-Tessier, Evelyne, Burnod, Alexis, Chvetzoff, Gisele, Poulain, Phillipe, Copel, Laure, Cottu, Paul, Pierga, Jean-Yves, Brédart, Anne, Dolbeault, Sylvie

“…Advance care planning is essential to enable informed medical decisions to be made and to reduce aggressiveness in end-of-life (EOL) care. This study aimed to…”
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Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer by Corpet, Armelle, De Koning, Leanne, Toedling, Joern, Savignoni, Alexia, Berger, Frédérique, Lemaître, Charlène, O'Sullivan, Roderick J, Karlseder, Jan, Barillot, Emmanuel, Asselain, Bernard, Sastre-Garau, Xavier, Almouzni, Geneviève

“…Mammalian cells possess two isoforms of the histone H3–H4 chaperone anti‐silencing function 1 (Asf1), Asf1a and Asf1b. However to date, whether they have…”
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Addressing the issue of bias in observational studies: Using instrumental variables and a quasi-randomization trial in an ESME research project by Ezzalfani, Monia, Porcher, Raphaël, Savignoni, Alexia, Delaloge, Suzette, Filleron, Thomas, Robain, Mathieu, Pérol, David

“…Purpose Observational studies using routinely collected data are faced with a number of potential shortcomings that can bias their results. Many methods rely…”
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Impact of body mass index on overall survival in patients with metastatic breast cancer by Saleh, Khalil, Carton, Matthieu, Dieras, Véronique, Heudel, Pierre-Etienne, Brain, Etienne, D’Hondt, Véronique, Mailliez, Audrey, Patsouris, Anne, Mouret-Reynier, Marie-Ange, Goncalves, Anthony, Ferrero, Jean Marc, Petit, Thierry, Emile, George, Uwer, Lionel, Debled, Marc, Dalenc, Florence, Jouannaud, Christelle, Ladoire, Sylvain, Leheurteur, Marianne, Cottu, Paul, Veron, Lucie, Savignoni, Alexia, Courtinard, Coralie, Robain, Mathieu, Delaloge, Suzette, Deluche, Elise

“…High Body mass index (BMI) is a risk factor for breast cancer among postmenopausal women and an adverse prognostic factor in early-stage. Little is known about…”
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Toxicity of locoregional radiotherapy in combination with bevacizumab in patients with non-metastatic breast cancer (TOLERAB): Final long-term evaluation by Clément-Zhao, Alice, Tanguy, Marie-Laure, Cottu, Paul, De La Lande, Brigitte, Bontemps, Patrick, Lemanski, Claire, Baumann, Pierre, Savignoni, Alexia, Levy, Christelle, Peignaux, Karine, Reynaud-Bougnoux, Agnès, Gobillion, Aline, Kirova, Youlia

“…Few data are available concerning the safety of bevacizumab (B) in combination with locoregional radiation therapy (RT). The objective of this study was to…”
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Results of a Multicenter Prospective Study on the Postoperative Treatment of Unilateral Retinoblastoma After Primary Enucleation by Aerts, Isabelle, Sastre-Garau, Xavier, Savignoni, Alexia, Lumbroso-Le Rouic, Livia, Thebaud-Leculée, Estelle, Frappaz, Didier, Coze, Carole, Thomas, Caroline, Gauthier-Villars, Marion, Lévy-Gabriel, Christine, Brisse, Hervé J, Desjardins, Laurence, Doz, François

“…The objective of this prospective study was to assess overall survival and event-free survival in patients with intraocular unilateral retinoblastoma…”
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Beyond Axillary Lymph Node Metastasis, BMI and Menopausal Status Are Prognostic Determinants for Triple-Negative Breast Cancer Treated by Neoadjuvant Chemotherapy by Bonsang-Kitzis, Hélène, Chaltier, Léonor, Belin, Lisa, Savignoni, Alexia, Rouzier, Roman, Sablin, Marie-Paule, Lerebours, Florence, Bidard, François-Clément, Cottu, Paul, Sastre-Garau, Xavier, Laé, Marick, Pierga, Jean-Yves, Reyal, Fabien

“…Triple-negative breast cancers (TNBC) are a specific subtype of breast cancers with a particularly poor prognosis. However, it is a very heterogeneous subgroup…”
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Prognostic value of CEC count in HER2-negative metastatic breast cancer patients treated with bevacizumab and chemotherapy: a prospective validation study (UCBG COMET) by Vasseur, Antoine, Cabel, Luc, Tredan, Olivier, Chevrier, Marion, Dubot, Coraline, Lorgis, Véronique, Jacot, William, Goncalves, Anthony, Debled, Marc, Levy, Christelle, Ferrero, Jean-Marc, Jouannaud, Christelle, Luporsi, Elisabeth, Mouret-Reynier, Marie-Ange, Dalenc, Florence, Lemonnier, Jerome, Savignoni, Alexia, Tanguy, Marie-Laure, Bidard, Francois-Clement, Pierga, Jean-Yves

“…Background Proof of concept studies has reported that circulating endothelial cell (CEC) count may be associated with the outcome of HER2-negative metastatic…”
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The histone chaperone HJURP is a new independent prognostic marker for luminal A breast carcinoma by Montes de Oca, Rocío, Gurard-Levin, Zachary A., Berger, Frédérique, Rehman, Haniya, Martel, Elise, Corpet, Armelle, de Koning, Leanne, Vassias, Isabelle, Wilson, Laurence O.W., Meseure, Didier, Reyal, Fabien, Savignoni, Alexia, Asselain, Bernard, Sastre-Garau, Xavier, Almouzni, Geneviève

“…Breast cancer is a heterogeneous disease with different molecular subtypes that have varying responses to therapy. An ongoing challenge in breast cancer…”
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Safety profile of subcutaneous trastuzumab in patients with HER2-positive early breast cancer: The French HERmione non-interventional prospective study by Jacquin, Jean-Philippe, Uwer, Lionel, Savignoni, Alexia, Ferrero, Jean-Marc, Lortholary, Alain, Solub, David, Delaporte, Flore, Chalabi, Nassera, Pibre, Sophie, Belkacemi, Yazid

“…HERmione study was conducted to assess, in human epidermal growth factor receptor 2 (HER2)-positive early breast cancer (eBC), the safety profile of…”
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Breast-Conserving Treatment in the Elderly: Long-Term Results of Adjuvant Hypofractionated and Normofractionated Radiotherapy by Kirova, Youlia M., M.D, Campana, Francois, M.D, Savignoni, Alexia, M.D, Laki, Fatima, M.D, Muresan, Marius, M.D, Dendale, Remi, M.D, Bollet, Marc A., M.D, Salmon, Remy J., M.D, Fourquet, Alain, M.D

“…Purpose To evaluate the long-term cause-specific survival (CSS), locoregional recurrence-free survival (LRFS), and metastases-free survival (MFS) in elderly…”
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Analysis of ototoxicity in young children receiving carboplatin in the context of conservative management of unilateral or bilateral retinoblastoma by Jehanne, Mathilde, Lumbroso-Le Rouic, Livia, Savignoni, Alexia, Aerts, Isabelle, Mercier, Ghislaine, Bours, Danielle, Desjardins, Laurence, Doz, François

“…Background Carboplatin plays an important role in the conservative management of retinoblastoma, but is associated with risk of ototoxicity in these young…”
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Digital Display Precision Predictor: the prototype of a global biomarker model to guide treatments with targeted therapy and predict progression-free survival by Lazar, Vladimir, Magidi, Shai, Girard, Nicolas, Savignoni, Alexia, Martini, Jean-François, Massimini, Giorgio, Bresson, Catherine, Berger, Raanan, Onn, Amir, Raynaud, Jacques, Wunder, Fanny, Berindan-Neagoe, Ioana, Sekacheva, Marina, Braña, Irene, Tabernero, Josep, Felip, Enriqueta, Porgador, Angel, Kleinman, Claudia, Batist, Gerald, Solomon, Benjamin, Tsimberidou, Apostolia Maria, Soria, Jean-Charles, Rubin, Eitan, Kurzrock, Razelle, Schilsky, Richard L.

“…The expanding targeted therapy landscape requires combinatorial biomarkers for patient stratification and treatment selection. This requires simultaneous…”
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A prognostic DNA signature for T1T2 node-negative breast cancer patients by Gravier, Eléonore, Pierron, Gaëlle, Vincent-Salomon, Anne, Gruel, Nadège, Raynal, Virginie, Savignoni, Alexia, De Rycke, Yann, Pierga, Jean-Yves, Lucchesi, Carlo, Reyal, Fabien, Fourquet, Alain, Roman-Roman, Sergio, Radvanyi, François, Sastre-Garau, Xavier, Asselain, Bernard, Delattre, Olivier

“…Predicting evolution of small node‐negative breast carcinoma is a real challenge in clinical practice. The aim of this study was to search whether qualitative…”
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Helping Patients Communicate With Oncologists When Cancer Treatment Resistance Occurs to Develop, Test, and Implement a Patient Communication Aid: Sequential Collaborative Mixed Methods Study by Brédart, Anne, Rault, Aude, Terrasson, Johanna, Seigneur, Etienne, De Koning, Leanne, Hess, Elisabeth, Savignoni, Alexia, Cottu, Paul, Pierga, Jean-Yves, Piperno-Neumann, Sophie, Rodrigues, Manuel, Bouleuc, Carole, Dolbeault, Sylvie

“…Most cancer-related deaths result from disseminated diseases that develop resistance to anticancer treatments. Inappropriate communication in this challenging…”
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Long-term prognostic performance of Ki67 rate in early stage, pT1-pT2, pN0, invasive breast carcinoma by Reyal, Fabien, Hajage, David, Savignoni, Alexia, Feron, Jean-Guillaume, Bollet, Marc Andrew, Kirova, Youlia, Fourquet, Alain, Pierga, Jean-Yves, Cottu, Paul, Dieras, Veronique, Fourchotte, Virginie, Laki, Fatima, Alran, Severine, Asselain, Bernard, Vincent-Salomon, Anne, Sigal-Zafrani, Brigitte, Sastre-Garau, Xavier

“…Molecular signatures may become of use in clinical practice to assess the prognosis of breast cancers. However, although international consensus conferences…”
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External validation of Adjuvant! Online breast cancer prognosis tool. Prioritising recommendations for improvement by Hajage, David, de Rycke, Yann, Bollet, Marc, Savignoni, Alexia, Caly, Martial, Pierga, Jean-Yves, Horlings, Hugo M, Van de Vijver, Marc J, Vincent-Salomon, Anne, Sigal-Zafrani, Brigitte, Senechal, Claire, Asselain, Bernard, Sastre, Xavier, Reyal, Fabien

“…Adjuvant! Online is a web-based application designed to provide 10 years survival probability of patients with breast cancer. Several predictors have not been…”
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Correction: Beyond Axillary Lymph Node Metastasis, BMI and Menopausal Status Are Prognostic Determinants for Triple-Negative Breast Cancer Treated by Neoadjuvant Chemotherapy by Bonsang-Kitzis, Hélène, Chaltier, Léonor, Belin, Lisa, Savignoni, Alexia, Rouzier, Roman, Hamy, Anne-Sophie, Sablin, Marie-Paule, Lerebours, Florence, Bidard, François-Clément, Cottu, Paul, Sastre-Garau, Xavier, Laé, Marick, Pierga, Jean-Yves, Reyal, Fabien

“…[This corrects the article DOI: 10.1371/journal.pone.0144359.]…”
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Risk of breast cancer recurrence and contralateral breast cancer in relation to BRCA1 and BRCA2 mutation status following breast-conserving surgery and radiotherapy by Kirova, Youlia M., Stoppa-Lyonnet, Dominique, Savignoni, Alexia, Sigal-Zafrani, Brigitte, Fabre, Nicolas, Fourquet, Alain

“…BRCA1 and BRCA2 germline mutations are associated with a strong risk of breast cancer, which may preclude breast-conserving treatment in carriers. This study…”
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Is Radiotherapy an Option for Early Breast Cancers With Complete Clinical Response After Neoadjuvant Chemotherapy? by Daveau, Caroline, M.D, Savignoni, Alexia, M.D, Abrous-Anane, Soumya, M.D, Pierga, Jean-Yves, M.D., Ph.D, Reyal, Fabien, M.D., Ph.D, Gautier, Chantal, Kirova, Youlia M., M.D, Dendale, Rémi, M.D, Campana, François, M.D, Fourquet, Alain, M.D, Bollet, Marc A., M.D., Ph.D

“…Purpose To determine whether the exclusive use of radiotherapy (ERT) could be a treatment option after complete clinical response (cCR) to neoadjuvant…”
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