Search Results - "SAVAGE, Daniel D"

Sexually dimorphic organization of open field behavior following moderate prenatal alcohol exposure by Osterlund Oltmanns, Jenna R., Schaeffer, Ericka A., Goncalves Garcia, Monica, Donaldson, Tia N., Acosta, Gabriela, Sanchez, Lilliana M., Davies, Suzy, Savage, Daniel D., Wallace, Douglas G., Clark, Benjamin J.

“…Background Prenatal alcohol exposure (PAE) can produce deficits in a wide range of cognitive functions but is especially detrimental to behaviors requiring…”
Get full text

Effect of moderate prenatal ethanol exposure on the differential expression of two histamine H3 receptor isoforms in different brain regions of adult rat offspring by Davies, Suzy, Lujan, Kiana S, Rappaport, Ella J, Valenzuela, Carlos F, Savage, Daniel D

“…We have reported that prenatal alcohol exposure (PAE) elevates histamine H receptor (H3R) agonist-mediated inhibition of glutamatergic neurotransmission in the…”
Get full text

Prenatal alcohol exposure alters mRNA expression for stress peptides, glucocorticoid receptor function and immune factors in acutely stressed neonatal brain by Ruffaner-Hanson, Chaselyn D, Fernandez-Oropeza, Annette K, Sun, Melody S, Caldwell, Kevin K, Allan, Andrea M, Savage, Daniel D, Valenzuela, C Fernando, Noor, Shahani, Milligan, Erin D

“…The amygdala, hippocampus and hypothalamus are critical stress regulatory areas that undergo functional maturation for stress responding initially established…”
Get full text

Prenatal Alcohol Exposure Impairs the Placenta–Cortex Transcriptomic Signature, Leading to Dysregulation of Angiogenic Pathways by Sautreuil, Camille, Lecointre, Maryline, Derambure, Céline, Brasse-Lagnel, Carole, Leroux, Philippe, Laquerrière, Annie, Nicolas, Gaël, Gil, Sophie, Savage, Daniel D, Marret, Stéphane, Marguet, Florent, Falluel-Morel, Anthony, Gonzalez, Bruno J

“…Although alcohol consumption during pregnancy is a major cause of behavioral and learning disabilities, most FASD infants are late- or even misdiagnosed due to…”
Get full text

Prenatal alcohol exposure dysregulates spinal and circulating immune cell circular RNA expression in adult female rats with chronic sciatic neuropathy by Noor, Shahani, Pritha, Ariana N, Pasmay, Andrea A, Sanchez, Jacob E, Sanchez, Joshua J, Fernandez-Oropeza, Annette K, Sun, Melody S, Dell'Orco, Michela, Davies, Suzy, Savage, Daniel D, Mellios, Nikolaos, Milligan, Erin D

“…Alcohol consumption during pregnancy is associated with Fetal Alcohol Spectrum Disorders (FASD) that results in a continuum of central nervous system (CNS)…”
Get full text

Effects of moderate prenatal ethanol exposure and age on social behavior, spatial response perseveration errors and motor behavior by Hamilton, Derek A., Barto, Daniel, Rodriguez, Carlos I., Magcalas, Christy M., Fink, Brandi C., Rice, James P., Bird, Clark W., Davies, Suzy, Savage, Daniel D.

“…•Prenatal ethanol exposure impaired social behavior and tongue protrusion.•Behavioral deficits suggest alterations in ventrolateral frontal cortex…”
Get full text

Prenatal alcohol exposure potentiates chronic neuropathic pain, spinal glial and immune cell activation and alters sciatic nerve and DRG cytokine levels by Noor, Shahani, Sanchez, Joshua J, Vanderwall, Arden G, Sun, Melody S, Maxwell, Jessie R, Davies, Suzy, Jantzie, Lauren L, Petersen, Timothy R, Savage, Daniel D, Milligan, Erin D

“…Highlights • Moderate prenatal alcohol exposure (PAE) potentiates chronic neuropathic pain. • PAE induces exaggerated spinal glial activation following…”
Get full text

Ifenprodil infusion in agranular insular cortex alters social behavior and vocalizations in rats exposed to moderate levels of ethanol during prenatal development by Bird, Clark W., Barto, Daniel, Magcalas, Christy M., Rodriguez, Carlos I., Donaldson, Tia, Davies, Suzy, Savage, Daniel D., Hamilton, Derek A.

“…•Ifenprodil infusion into agranular insular cortex alters social behaviors in rats.•Many effects of ifenprodil infusion on behaviors are specific to PAE…”
Get full text

Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex by Bird, Clark W, Candelaria-Cook, Felicha T, Magcalas, Christy M, Davies, Suzy, Valenzuela, C Fernando, Savage, Daniel D, Hamilton, Derek A

“…Prenatal exposure to alcohol affects the expression and function of glutamatergic neurotransmitter receptors in diverse brain regions. The present study was…”
Get full text

Ethanol-Induced Alterations in Placental and Fetal Cerebrocortical Annexin-A4 and Cerebral Cavernous Malformation Protein 3 Are Associated With Reductions in Fetal Cortical VEGF Receptor Binding and Microvascular Density by Savage, Daniel D., Rosenberg, Martina J., Coquet, Laurent, Porch, Morgan W., Allen, Nyika A., Roux, Christian, Aligny, Caroline, Jouenne, Thierry, Gonzalez, Bruno J.

“…Gonzalez and colleagues have reported prenatal alcohol exposure (PAE)-induced reductions of angiogenesis-related proteins in mouse placenta. These effects were…”
Get full text

Targeting the β2-integrin LFA-1, reduces adverse neuroimmune actions in neuropathic susceptibility caused by prenatal alcohol exposure by Sanchez, Joshua J, Sanchez, Jacob E, Noor, Shahani, Ruffaner-Hanson, Chaselyn D, Davies, Suzy, Wagner, Carston R, Jantzie, Lauren L, Mellios, Nikolaos, Savage, Daniel D, Milligan, Erin D

“…Recently, moderate prenatal alcohol exposure (PAE) was shown to be a risk factor for peripheral neuropathy following minor nerve injury. This effect coincides…”
Get full text

Hypersynchrony in MEG spectral amplitude in prospectively-identified 6-month-old infants prenatally exposed to alcohol by Stephen, Julia M., Flynn, Lucinda, Kabella, Danielle, Schendel, Megan, Cano, Sandra, Savage, Daniel D., Rayburn, William, Leeman, Lawrence M., Lowe, Jean, Bakhireva, Ludmila N.

“…Early identification of children who experience developmental delays due to prenatal alcohol exposure (PAE) remains a challenge for individuals who do not…”
Get full text

Patterns of social-experience-related c- fos and Arc expression in the frontal cortices of rats exposed to saccharin or moderate levels of ethanol during prenatal brain development by Hamilton, Derek A., Candelaria-Cook, Felicha T., Akers, Katherine G., Rice, James P., Maes, Levi I., Rosenberg, Martina, Valenzuela, C. Fernando, Savage, Daniel D.

“…Recent findings from our laboratory indicate that alterations in frontal cortex function, structural plasticity, and related social behaviors are persistent…”
Get full text

Impact of two different rodent diets on maternal ethanol consumption, serum ethanol concentration and pregnancy outcome measures by Davies, Suzy, Nelson, Danika E., Shrestha, Sumi, Savage, Daniel D.

“…Recent studies report varying levels of ethanol consumption by rodents maintained on different commercially available laboratory diets. As varied ethanol…”
Get full text

The histamine H3 receptor inverse agonist SAR-152954 reverses deficits in long-term potentiation associated with moderate prenatal alcohol exposure by Goncalves-Garcia, Monica, Davies, Suzy, Savage, Daniel D., Hamilton, Derek A.

“…Prenatal alcohol exposure can have persistent effects on learning, memory, and synaptic plasticity. Previous work from our group demonstrated deficits in…”
Get full text

Organization of spontaneous spatial behaviors under dark conditions is unaffected in adult male and female long-Evans rats after moderate prenatal alcohol exposure by Schaeffer, Ericka A, LaCour, Ariyana, Donaldson, Tia N, Linsenbardt, David N, Davies, Suzy, Savage, Daniel D, Wallace, Douglas G, Clark, Benjamin J

“…Prenatal alcohol exposure can produce disruptions in a wide range of cognitive functions, but it is especially detrimental to spatial navigation. In open…”
Get full text

The effects of moderate prenatal alcohol exposure on performance in object and spatial discrimination tasks by adult male rats by Sanchez, Lilliana M., Acosta, Gabriela, Cushing, Sarah D., Johnson, Sarah A., Turner, Sean M., Davies, Suzy, Savage, Daniel D., Burke, Sara N., Clark, Benjamin J.

“…Exposure to alcohol during pregnancy produces Fetal Alcohol Spectrum Disorders, which in its most severe form is characterized by physical dysmorphology and…”
Get full text

Altered Hippocampal Place Cell Representation and Theta Rhythmicity following Moderate Prenatal Alcohol Exposure by Harvey, Ryan E., Berkowitz, Laura E., Savage, Daniel D., Hamilton, Derek A., Clark, Benjamin J.

“…Prenatal alcohol exposure (PAE) leads to profound deficits in spatial memory and synaptic and cellular alterations to the hippocampus that last into adulthood…”
Get full text

Prognostic Implications of Echocardiographically Determined Left Ventricular Mass in the Framingham Heart Study by Levy, Daniel, Garrison, Robert J, Savage, Daniel D, Kannel, William B, Castelli, William P

“…A pattern of left ventricular hypertrophy evident on the electrocardiogram is a harbinger of morbidity and mortality from cardiovascular disease…”
Get full text

Moderate prenatal alcohol exposure impairs performance by adult male rats in an object-place paired-associate task by Sanchez, Lilliana M., Goss, Jonathan, Wagner, Jennifer, Davies, Suzy, Savage, Daniel D., Hamilton, Derek A., Clark, Benjamin J.

“…Memory impairments, including spatial and object processing, are often observed in individuals with Fetal Alcohol Spectrum Disorders. The neurobiological basis…”
Get full text