Search Results - "SAUSBIER, M"

The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion by Rieg, T., Vallon, V., Sausbier, M., Sausbier, U., Kaissling, B., Ruth, P., Osswald, H.

“…The kidney is the major regulator of potassium homeostasis. In addition to the ROMK channels, large conductance Ca2+-activated K+ (BK) channels are expressed…”
Get full text

Cerebellar Ataxia and Purkinje Cell Dysfunction Caused by Ca2+-Activated K+Channel Deficiency by Sausbier, M., Hu, H., Arntz, C., Feil, S., Kamm, S., Adelsberger, H., Sausbier, U., Sailer, C. A., Feil, R., Hofmann, F., Korth, M., Shipston, M. J., H.-G. Knaus, Wolfer, D. P., Pedroarena, C. M., Storm, J. F., Ruth, P., Andersen, Per O.

“…Malfunctions of potassium channels are increasingly implicated as causes of neurological disorders. However, the functional roles of the large-conductance…”
Get full text

Two classes of outer hair cells along the tonotopic axis of the cochlea by Engel, J., Braig, C., Rüttiger, L., Kuhn, S., Zimmermann, U., Blin, N., Sausbier, M., Kalbacher, H., Münkner, S., Rohbock, K., Ruth, P., Winter, H., Knipper, M.

“…The molecular basis of high versus low frequency hearing loss and the differences in the sensitivity of outer hair cells depending on their cochlear…”
Get full text

Role of cholinergic-activated KCa1.1 (BK), KCa3.1 (SK4) and KV7.1 (KCNQ1) channels in mouse colonic Cl− secretion by Matos, J. E., Sausbier, M., Beranek, G., Sausbier, U., Ruth, P., Leipziger, J.

“…Aim:  Colonic crypts are the site of Cl− secretion. Basolateral K+ channels provide the driving force for luminal cystic fibrosis transmembrane…”
Get full text

The Role of BKCa Channels in Electrical Signal Encoding in the Mammalian Auditory Periphery by Oliver, Dominik, Taberner, Annette M, Thurm, Henrike, Sausbier, Matthias, Arntz, Claudia, Ruth, Peter, Fakler, Bernd, Liberman, M. Charles

“…Large-conductance voltage- and Ca(2+)-activated K+ channels (BKCa) are involved in shaping spiking patterns in many neurons. Less is known about their role in…”
Get full text

Structure and function of cGMP-dependent protein kinases by Pfeifer, A, Ruth, P, Dostmann, W, Sausbier, M, Klatt, P, Hofmann, F

Get more information

Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice by SAUSBIER, Matthias, AMTZ, Claudia, ABDULLAH, Usamah, KRIPPEIT-DREWS, Peter, FEIL, Robert, HOFMANN, Franz, KNAUS, Hans-Günier, KENYON, Chris, SHIPSTON, Michael J, STORM, Johan F, NEUHUBER, Winfried, KORTH, Michael, BUCURENCIU, Iancu, SCHUBERT, Rudolf, GOLLASCH, Maik, RUTH, Peter, HONG ZHAO, ZHOU, Xiao-Bo, SAUSBIER, Ulrike, FEIL, Susanne, KAMM, Simone, ESSIN, Kyrill, SAILER, Claudia A

“…Abnormally elevated blood pressure is the most prevalent risk factor for cardiovascular disease. The large-conductance, voltage- and Ca2+-dependent K+ (BK)…”
Get full text

Mechanisms of NO/cGMP-Dependent Vasorelaxation by Sausbier, Matthias, Schubert, Rudolf, Voigt, Viktor, Hirneiss, Christoph, Pfeifer, Alexander, Korth, Michael, Kleppisch, Thomas, Ruth, Peter, Hofmann, Franz

“…ABSTRACT—Both cGMP-dependent and -independent mechanisms have been implicated in the regulation of vascular tone by NO. We analyzed acetylcholine (ACh)- and…”
Get full text

Defective smooth muscle regulation in cGMP kinase I-deficient mice by Pfeifer, Alexander, Klatt, Peter, Massberg, Steffen, Ny, Lars, Sausbier, Matthias, Hirneiß, Christoph, Wang, Ge-Xing, Korth, Michael, Aszódi, Attila, Andersson, Karl-Erik, Krombach, Fritz, Mayerhofer, Artur, Ruth, Peter, Fässler, Reinhard, Hofmann, Franz

“…Regulation of smooth muscle contractility is essential for many important biological processes such as tissue perfusion, cardiovascular haemostasis and…”
Get full text

Reduced Inflammatory Hyperalgesia with Preservation of Acute Thermal Nociception in Mice Lacking cGMP-Dependent Protein Kinase I by Tegeder, Irmgard, Del Turco, Domenico, Schmidtko, Achim, Sausbier, Matthias, Feil, Robert, Hofmann, Franz, Deller, Thomas, Ruth, Peter, Geisslinger, Gerd, Beavo, Joseph A.

“…cGMP-dependent protein kinase I (PKG-I) has been suggested to contribute to the facilitation of nociceptive transmission in the spinal cord presumably by…”
Get full text

Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I by Massberg, S, Sausbier, M, Klatt, P, Bauer, M, Pfeifer, A, Siess, W, Fässler, R, Ruth, P, Krombach, F, Hofmann, F

“…Atherosclerotic vascular lesions are considered to be a major cause of ischemic diseases, including myocardial infarction and stroke. Platelet adhesion and…”
Get full text

The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion. Commentaries by SANSOM, S. C, WELLING, P. A, RIEG, T, VALLON, V, SAUSBIER, M, SAUSBIER, U, KAISSLING, B, RUTH, P, OSSWALD, H

Get full text

Role of cholinergic‐activated K Ca 1.1 (BK), K Ca 3.1 (SK4) and K V 7.1 (KCNQ1) channels in mouse colonic Cl − secretion by Matos, J. E., Sausbier, M., Beranek, G., Sausbier, U., Ruth, P., Leipziger, J.

“…Abstract Aim:  Colonic crypts are the site of Cl − secretion. Basolateral K + channels provide the driving force for luminal cystic fibrosis transmembrane…”
Get full text

Role of cholinergic-activated KCa I.I (BK), KCa3. I (SK4) and Kv7.1 (KCNQI) channels in mouse colonic Cl- secretion by MATES, J. E, SAUSBIER, M, BERANEK, G, SAUSBIER, U, RUTH, P, LEIPZIGER, J

Get full text

Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca super(2+)-activated K super(+) channel by Sausbier, M, Zhou, X-B, Beier, C, Sausbier, U, Wolpers, D, Maget, S, Martin, C, Dietrich, A, Ressmeyer, A-R, Renz, H, Schlossmann, J, Hofmann, F, Neuhuber, W, Gudermann, T

“…The unique voltage- and Ca super(2+)-dependent K super(+) (BK) channel, prominently expressed in airway smooth muscle cells, has been suggested as an important…”
Get full text

Cerebellar ataxia and Purkinje cell dysfunction caused by Ca 2+ -activated K + channel deficiency by Sausbier, M., Hu, H., Arntz, C., Feil, S., Kamm, S., Adelsberger, H., Sausbier, U., Sailer, C. A., Feil, R., Hofmann, F., Korth, M., Shipston, M. J., Knaus, H.-G., Wolfer, D. P., Pedroarena, C. M., Storm, J. F., Ruth, P.

“…Malfunctions of potassium channels are increasingly implicated as causes of neurological disorders. However, the functional roles of the large-conductance…”
Get full text

Cerebellar ataxia and Purkinje cell dysfunction caused by Ca super(2+)-activated K super(+) channel deficiency by Sausbier, M, Hu, H, Arntz, C, Feil, S, Kamm, S, Adelsberger, H, Sausbier, U, Sailer, CA, Feil, R, Hofmann, F, Korth, M, Shipston, MJ, Knaus, H-G, Wolfer, D P, Pedroarena, C M, Storm, J F, Ruth, P

“…Malfunctions of potassium channels are increasingly implicated as causes of neurological disorders. However, the functional roles of the large-conductance…”
Get full text