Search Results - "SATTLER, Julia M"
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Inter-subunit interactions drive divergent dynamics in mammalian and Plasmodium actin filaments
Published in PLoS biology (16-07-2018)“…Cell motility is essential for protozoan and metazoan organisms and typically relies on the dynamic turnover of actin filaments. In metazoans, monomeric actin…”
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2
The Actin Filament-Binding Protein Coronin Regulates Motility in Plasmodium Sporozoites
Published in PLoS pathogens (01-07-2016)“…Parasites causing malaria need to migrate in order to penetrate tissue barriers and enter host cells. Here we show that the actin filament-binding protein…”
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3
Experimental vaccination by single dose sporozoite injection of blood-stage attenuated malaria parasites
Published in EMBO molecular medicine (12-09-2024)“…Malaria vaccination approaches using live Plasmodium parasites are currently explored, with either attenuated mosquito-derived sporozoites or attenuated…”
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4
AAV8-Mediated In Vivo Overexpression of miR-155 Enhances the Protective Capacity of Genetically Attenuated Malarial Parasites
Published in Molecular therapy (01-12-2014)“…Malaria, caused by protozoan Plasmodium parasites, remains a prevalent infectious human disease due to the lack of an efficient and safe vaccine. This is…”
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5
SPOT: a web-tool enabling swift profiling of transcriptomes
Published in Bioinformatics (22-12-2021)“…Abstract The increasing number of single cell and bulk RNAseq datasets describing complex gene expression profiles in different organisms, organs or cell…”
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6
Identification of a Phosphotransferase System of Escherichia coli Required for Growth on N-Acetylmuramic Acid
Published in Journal of Bacteriology (01-04-2004)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
Immunization efficacy of cryopreserved genetically attenuated Plasmodium berghei sporozoites
Published in Parasitology research (1987) (01-08-2018)“…Malaria is transmitted through the injection of Plasmodium sporozoites into the skin by Anopheles mosquitoes. The parasites first replicate within the liver…”
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8
Crystal Structures Explain Functional Differences in the Two Actin Depolymerization Factors of the Malaria Parasite
Published in The Journal of biological chemistry (12-08-2011)“…Apicomplexan parasites, such as the malaria-causing Plasmodium, utilize an actin-based motor for motility and host cell invasion. The actin filaments of these…”
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9
Chemical attenuation of Plasmodium in the liver modulates severe malaria disease progression
Published in The Journal of immunology (1950) (15-05-2015)“…Cerebral malaria is one of the most severe complications of malaria disease, attributed to a complicated series of immune reactions in the host. The syndrome…”
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10
Crystal structures explain functional differences in the two actin depolymerization factors of the malaria parasite
Published in The Journal of biological chemistry (12-08-2011)“…Apicomplexan parasites, such as the malaria-causing Plasmodium , utilize an actin-based motor for motility and host cell invasion. The actin filaments of these…”
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11
In vitro activity of wALADin benzimidazoles against different life cycle stages of Plasmodium parasites
Published in Antimicrobial agents and chemotherapy (01-01-2015)“…wALADin1 benzimidazoles are specific inhibitors of δ-aminolevulinic acid dehydratase from Wolbachia endobacteria of filarial nematodes. We report that wALADin1…”
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12
A suggested vital function for eIF‐5A and dhs genes during murine malaria blood‐stage infection
Published in FEBS open bio (01-08-2016)“…The biological function of the post‐translational modification hypusine in the eukaryotic initiation factor 5A (EIF‐5A) in eukaryotes is still not understood…”
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13
Structure and Function of a G-actin Sequestering Protein with a Vital Role in Malaria Oocyst Development inside the Mosquito Vector
Published in The Journal of biological chemistry (09-04-2010)“…Cyclase-associated proteins (CAPs) are evolutionary conserved G-actin-binding proteins that regulate microfilament turnover. CAPs have a modular structure…”
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14
Novel TypeII Fatty Acid Biosynthesis (FAS II) Inhibitors as Multistage Antimalarial Agents
Published in ChemMedChem (01-03-2013)“…Malaria is a potentially fatal disease caused by Plasmodium parasites and poses a major medical risk in large parts of the world. The development of new,…”
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15
Plasmodium Sporozoite Motility on Flat Substrates
Published in Bio-protocol (20-07-2017)“…sporozoites are the infectious, highly motile forms of the malaria parasite transmitted by mosquitoes. Sporozoite motility can be assessed following the…”
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16
Novel Type II Fatty Acid Biosynthesis (FAS II) Inhibitors as Multistage Antimalarial Agents
Published in ChemMedChem (01-03-2013)“…Malaria is a potentially fatal disease caused by Plasmodium parasites and poses a major medical risk in large parts of the world. The development of new,…”
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Journal Article -
17
Crystallization and preliminary structural characterization of the two actin-depolymerization factors of the malaria parasite
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-05-2010)“…The malaria parasite Plasmodium depends on its actin‐based motor system for motility and host‐cell invasion. Actin‐depolymerization factors are important…”
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