Search Results - "SATTERWHITE, J"

Effects of a γ-secretase inhibitor in a randomized study of patients with Alzheimer disease by SIEMERS, E. R, QUINN, J. F, SATTERWHITE, J, GONZALES, C, DEAN, R. A, MAY, P. C, KAYE, J, FARLOW, M. R, PORSTEINSSON, A, TARIOT, P, ZOULNOUNI, P, GALVIN, J. E, HOLTZMAN, D. M, KNOPMAN, D. S

“…LY450139 dihydrate, a gamma-secretase inhibitor, was studied in a randomized, controlled trial of 70 patients with Alzheimer disease. Subjects were given 30 mg…”
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MondoA-Mlx Heterodimers Are Candidate Sensors of Cellular Energy Status: Mitochondrial Localization and Direct Regulation of Glycolysis by Sans, Christopher L., Satterwhite, Daniel J., Stoltzman, Carrie A., Breen, Kevin T., Ayer, Donald E.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Early Changes in Biochemical Markers of Bone Formation Predict BMD Response to Teriparatide in Postmenopausal Women With Osteoporosis by Chen, Peiqi, Satterwhite, Julie H, Licata, Angelo A, Lewiecki, E Michael, Sipos, Adrien A, Misurski, Derek M, Wagman, Rachel B

“…The relationship between early changes in biochemical markers of bone turnover and the subsequent BMD response to daily teriparatide therapy in women with…”
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A thermodynamic analysis of end-directed particle flocking in chemical systems by De Bari, B., Dixon, J., Pateras, J., Rusling, J., Satterwhite-Warden, J., Vaidya, A.

“…We discuss the thermodynamics behind self-organizing Benzoquinone (BQ) particles on air–water interface. Experiments (Satterwhite-Warden et al., 2015; Chen…”
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Feasibility and Acceptability of a Pharmacogenomic Decision Support System in Palliative Care by Bull, Janet H, Bice, Tyler, Satterwhite, Wesley J, Massie, Lisa, Burpee, Elizabeth, Knotkova, Helena, Portenoy, Russell K

“…Pharmacogenomic analysis may improve the efficacy or safety of the drugs used in palliative care. Decision support systems may promote clinical integration of…”
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Anabolic and catabolic bone effects of human parathyroid hormone (1-34) are predicted by duration of hormone exposure by Frolik, Charles A, Black, Elwood C, Cain, Ricky L, Satterwhite, Julie H, Brown-Augsburger, Patricia L, Sato, Masahiko, Hock, Janet M

“…Parathyroid hormone (PTH)(1-34), given once daily, increases bone mass in a variety of animal models and humans with osteoporosis. However, continuous PTH…”
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The Human Papilloma Virus E7 Oncoprotein Inhibits Transforming Growth Factor-β Signaling by Blocking Binding of the Smad Complex to Its Target Sequence by Lee, Dug Keun, Kim, Byung-Chul, Kim, Isaac Yi, Cho, Eun-ah, Satterwhite, Daniel J., Kim, Seong-Jin

“…The human papillomavirus (HPV) oncoprotein E7 is implicated in the etiology of cervical cancer associated with infection by HPV. HPV-positive cells develop…”
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TGF‐β induces novel Lef‐1 splice variants through a Smad‐independent signaling pathway by Cordray, Pauline, Satterwhite, Daniel J.

“…The lymphoid enhancer‐binding factor (Lef‐1) transcription factor is best known for the ability to transduce Wnt signals during development and to mediate…”
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TGF-beta targets the Wnt pathway components, APC and beta-catenin, as Mv1Lu cells undergo cell cycle arrest by Satterwhite, Daniel J, Neufeld, Kristi L

“…The highly coordinated interaction of TGF-beta and Wnt signaling pathways is critical for normal development. However, the effects of TGF-beta on APC and…”
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Use of IV isoproterenol test as a biomarker in a first-in-man study: Pilot investigation with LY, a combined beta3 agonist/beta1 antagonist by Satterwhite, J., Virgilio, S., VanLier, J.J., Gaich, G., Chalon, S.

“…Background LY is a selective β3‐agonist with β1‐antagonist properties that is expected to induce a β3‐mediated increase in thermogenesis. The IV isoproterenol…”
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The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer disease by Bodick, N C, Offen, W W, Shannon, H E, Satterwhite, J, Lucas, R, van Lier, R, Paul, S M

“…The therapeutic effects of selective cholinergic replacement using oral xanomeline, an m1/m4 receptor agonist, were assessed in a multicenter study of 343…”
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The safety and tolerance of xanomeline tartrate in patients with Alzheimer's disease by Sramek, J J, Hurley, D J, Wardle, T S, Satterwhite, J H, Hourani, J, Dies, F, Cutler, N R

“…Xanomeline tartrate (active ingredient xanomeline) is a muscarinic agonist that has demonstrated specificity for the M1 receptor in preclinical studies and has…”
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TGF-β Targets the Wnt Pathway Components, APC and β-catenin, as Mv1Lu Cells Undergo Cell Cycle Arrest by Satterwhite, Daniel J., Neufeld, Kristi L.

“…The highly coordinated interaction of TGF-? and Wnt signaling pathways is critical for normal development. However, the effects of TGF-β on APC and…”
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The Skeletal Response to Teriparatide Is Largely Independent of Age, Initial Bone Mineral Density, and Prevalent Vertebral Fractures in Postmenopausal Women With Osteoporosis by Marcus, Robert, Wang, Ouhong, Satterwhite, Julie, Mitlak, Bruce

“…In a recent study of women with postmenopausal osteoporosis, treatment with teriparatide for a median of 19 months increased bone mineral density and decreased…”
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Safety, tolerability, and changes in amyloid beta concentrations after administration of a gamma-secretase inhibitor in volunteers by Siemers, Eric, Skinner, Michael, Dean, Robert A, Gonzales, Celedon, Satterwhite, Julie, Farlow, Martin, Ness, Daniel, May, Patrick C

“…Amyloid beta (Abeta) may play a central role in the pathogenesis of Alzheimer disease. A functional gamma-secretase inhibitor, LY450139, was developed that…”
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Effects of age and dose on the pharmacokinetics of ibuprofen in the rat by Satterwhite, J H, Boudinot, F D

“…The pharmacokinetics of ibuprofen after 2.5 and 25 mg/kg doses were examined in young adult (5 months) and senescent (24 months) male Fischer 344 rats. Plasma…”
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Social Compatibility as a Consideration in Caring for Nursing Home Residents With Dementia by Cherry, Barbara, Carpenter, Ken, Waters, Cheryl, Hawkins, W.W., McGrew, Pamela, Satterwhite, Leah J., Stepien, Julie, Ruppelt, Wanda, Herring, Kent

“…A major challenge for caregivers in nursing homes is to provide high-quality, person-centered care to a large population of residents with Alzheimer's disease…”
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Effects of age on the pharmacodynamics of naproxen in the rat by Satterwhite, Julia H., Boudinot, F.Douglas

“…The pharmacodynamics of naproxen were evaluated in 5- and 24-month-old male Fischer 344 rats. Plasma naproxen concentrations and thromboxane B2 (T×B 2)…”
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Pharmacokinetics of ketoprofen in rats: effect of age and dose by Satterwhite, J H, Boudinot, F D

“…The effects of age and dose on the pharmacokinetics of ketoprofen were evaluated in young adult and senescent male Fischer 344 rats following intravenous…”
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Pharmacokinetics of cefaclor AF: effects of age, antacids and H2-receptor antagonists by Satterwhite, J H, Cerimele, B J, Coleman, D L, Hatcher, B L, Kisicki, J, DeSante, K A

“…The pharmacokinetics and bioavailability of cefaclor advanced formulation (cefaclor AF) were investigated in two studies, one comparing healthy elderly and…”
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